Chronic spontaneous urticaria
Immunological events in chronic spontaneous urticaria
... Chronic spontaneous urticaria (CSU) is a highly debilitating skin disease associated with systemic features. We have made significant progress in several aspects relating to this condition. However, ...
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Retrospective case note review of chronic spontaneous urticaria outcomes and adverse effects in patients treated with omalizumab or ciclosporin in UK secondary care.
... in urticaria symptoms, dermatologic‑related quality of life, and urticaria‑specific quality of life: are they telling us the same thing about response to treatment for chronic ...
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Increased serum complement C3 and C4 concentrations and their relation to severity of chronic spontaneous urticaria and CRP concentration
... Chronic spontaneous urticaria (CU) is associated with systemic inflammation and neuroimmunendocrine dys- function, during which the acute phase response (APR) and coagulation/firbrinolysis processes ...
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Assessment of effectiveness and safety of omalizumab in the treatment of chronic spontaneous urticaria
... Omalizumab is the third line of management in the treatment of chronic spontaneous urticaria refractory to four-fold increase in 2 nd generation antihistamines. In this study, a study population of ...
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Looking forward to new targeted treatments for chronic spontaneous urticaria
... of chronic spontaneous urticaria (CSU) has markedly improved the therapeutic possibilities for both, patients and physicians dealing with this disabling ...Keywords: Chronic spontaneous ...
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Stress, pseudoallergens, autoimmunity, infection and inflammation in chronic spontaneous urticaria
... Chronic spontaneous urticaria (CSU) is often associated with organ specific autoimmunity but is rarely caused by food ...CSU. Chronic underlying infection and mental and emotional stress can ...
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ASSURE-CSU: a real-world study of burden of disease in patients with symptomatic chronic spontaneous urticaria
... [1]. Chronic spontaneous urticaria (CSU), formerly known as chronic idiopathic urticaria (CIU) is defined by the spontaneous develop- ment of itchy hives and/or angioedema that ...
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To study the association of chronic spontaneous urticaria with anti thyroid peroxidase antibody and ASST
... of chronic urticaria were included in the ...of chronic spontaneous urticaria were identified based on history, examination and routine laboratory ...of urticaria or drugs for ...
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Relationship between vitamin D status and the inflammatory state in patients with chronic spontaneous urticaria
... Background: Chronic spontaneous urticaria (CSU) is an immune-inflammatory disease, characterized by acute phase response (APR) and immune activation. There has been increasing evidence showing that ...
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The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria
... It is known that IL-6-CRP signaling plays an impor- tant role in CSU. Interestingly, it has been suggested that IL-17 stimulates CRP expression independently of IL-1 Fig. 1 Plasma IL‑17 concentration in chronic ...
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Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria
... Background: There is increasing evidence pointing to the important role of tumor necrosis factor‑alpha (TNF‑α), a key inflammatory and apoptotic mediator in urticarial inflammation. However, the role of the TNF‑α system ...
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Management of chronic spontaneous urticaria (CSU): a treat to target approach using a patient reported outcome
... Chronic spontaneous urticaria is similar in many aspects to chronic diseases for which a T2T approach has been ...the Urticaria Activity Score 7 (UAS7), allows clinicians to monitor ...
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<p>Omalizumab for chronic spontaneous urticaria in “complex” patients: data from real-life clinical practice</p>
... by chronic spontaneous urticaria were ...of chronic spontaneous urticaria and an amelioration of quality of life within our ...for chronic spontaneous ...
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Can vitamin D, B12, folic acid, inflammatory markers and H. pylori effective in the process of chronic spontaneous urticaria?
... Background: Etiopathogenesis in Chronic Spontaneous Urticaria (CSU) is not completely clear. Some vitamins, inflammatory markers and even some microorganisms have been held responsible for this ...
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Increased platelet activating factor levels in chronic spontaneous urticaria predicts refractoriness to antihistamine treatment: an observational study
... urticaria duration (r = − 0.121, p = 0.045), while no cor- relation was found with UAS7 (r = 0.07, p = 0.215). PAF- AH showed positive correlations with C3 (r = 0.163, p = 0.007) and C4 (r = 0.185, p = 0.002) ...
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Profile of omalizumab in the treatment of chronic spontaneous urticaria
... acute urticaria; chronic urticaria (CU) is defined as wheals or angioedema, or both, occurring intermittently or continuously for at least 6 ...subtypes: spontaneous and inducible by physical ...
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On the Lipophilic Nature of Autoreactive IgE in Chronic Spontaneous Urticaria
... Chronic spontaneous urticaria (CSU) is an itching, mast cell-driven skin disease characterized by the recurrence of transient wheals, angioedema, or both for more than six weeks ...
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Economic burden of refractory chronic spontaneous urticaria on Kuwait's health system
... The following data were obtained from patient databases in 2014: demographic information, history of CSU, onset, severity of the disease, presence of angioedema, number of exacerba- tions of urticaria and ...
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Cost Utility of Omalizumab Compared with Standard of Care for the Treatment of Chronic Spontaneous Urticaria.
... Relapse probabilities for patients receiving SOC (those in the SOC arm or those who had discontinued omalizumab) were determined for each health state from patient-level data sourced from the 16-week follow-up period ...
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Interplay between acute phase response and coagulation/fibrinolysis in chronic spontaneous urticaria
... In the present study, markers of acute phase response (IL-6 and CRP) and of fibrin turnover (D-dimer) were associated with each other in CSU patients. These find- ings may relate to the association of inflammation and ...
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