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Chronic traumatic encephalopathy (CTE)

Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy

Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy

... The chronic effects of repetitive head impacts (RHI) on the development of neuroinflammation and its relationship to chronic traumatic encephalopathy (CTE) are ...than CTE were ...

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Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome

Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome

... designation, chronic traumatic encephalopathy (CTE), has been employed since the mid-1900s and has been used in recent years to describe a neurodegenerative disease found not just in boxers ...

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Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy

Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy

... mild traumatic brain injuries (rmTBI) are associated with cognitive deficits, inflammation, and stress-related ...of chronic traumatic encephalopathy (CTE) to study the ...

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Concussions and Contracts: The National Football League's Limitations to Protecting Its Players from Chronic Traumatic Encephalopathy

Concussions and Contracts: The National Football League's Limitations to Protecting Its Players from Chronic Traumatic Encephalopathy

... Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative brain injury that has become prevalent among high-contact professional sports, especially American ...of CTE and being ...

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Co-occurrence of chronic traumatic encephalopathy and prion disease

Co-occurrence of chronic traumatic encephalopathy and prion disease

... Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive traumatic brain injury ...(TBI). CTE is generally found in athletes participating ...

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Variation in TMEM106B in chronic traumatic encephalopathy

Variation in TMEM106B in chronic traumatic encephalopathy

... of chronic traumatic encephalopathy (CTE) is poorly ...with CTE risk, pathological features, and ante-mortem ...of CTE without comorbid neurodegenerative disease were genotyped ...

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Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer

Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer

... Chronic traumatic encephalopathy (CTE), previously known as punch-drunk syndrome or dementia pugilistica, is a neurodegenerative tauopathy caused by repetitive and cumulative head ...trauma. ...

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Clustering of tau-immunoreactive pathology in chronic traumatic encephalopathy

Clustering of tau-immunoreactive pathology in chronic traumatic encephalopathy

... Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder which may result from repetitive brain ...in CTE, clustering of the tau-immunoreactive pathology was studied in ...

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A Review of Traumatic Brain Injury Animal Models: Are We Lacking Adequate Models Replicating Chronic Traumatic Encephalopathy?

A Review of Traumatic Brain Injury Animal Models: Are We Lacking Adequate Models Replicating Chronic Traumatic Encephalopathy?

... ensuing encephalopathy later in life, leading to significant neurobehavioral and psychiatric ...of chronic traumatic encephalopathy in ...ideal CTE animal model for studying CTE ...

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PYRIMIDINE-4H-1OH DERIVATIVES RESTORE MITOCHONDRIAL FUNCTION IN EXPERIMENTAL CHRONIC TRAUMATIC ENCEPHALOPATHY

PYRIMIDINE-4H-1OH DERIVATIVES RESTORE MITOCHONDRIAL FUNCTION IN EXPERIMENTAL CHRONIC TRAUMATIC ENCEPHALOPATHY

... Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that develops with repeated exposure of the brain to a traumatic factor, ...severe traumatic brain injury ...

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Considerations for animal models of blast-related traumatic brain injury and chronic traumatic encephalopathy

Considerations for animal models of blast-related traumatic brain injury and chronic traumatic encephalopathy

... mild traumatic brain injury ...and chronic sequelae, including postconcussive syndrome, post-traumatic stress disorder, post-traumatic headache, and chronic traumatic ...

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Chronic traumatic encephalopathy: clinical‐biomarker correlations and current concepts in pathogenesis

Chronic traumatic encephalopathy: clinical‐biomarker correlations and current concepts in pathogenesis

... concussions. In the neocortex from military veterans, there were frequent perivascular and deep sulcal accumu- lations of NFT-like tau-positive neurons and glial cells as well as dystrophic axons were reported [58]. ...

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[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series

[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series

... the CTE cases, quanti- fied on immunostained sections containing multiple ROIs, significantly correlated with the levels of soluble p-tau monomers and oligomers, as assessed by Western blotting, and with tau ...

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Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study

Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study

... We investigated whether any MTL subregion is more susceptible to tau pathology in an early stage of CTE. Previous findings have highlighted that hippocampal CA4 and CA2 subfields are more prone to tau pathology in ...

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A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy

A quantitative study of tau pathology in eleven cases of chronic traumatic encephalopathy

... Third, CTE/ADNC cases were compared with ADNC cases not associated with CTE using a two-factor repeated measures ...11 CTE cases, the data were analysed using principal components analysis (PCA) ...

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Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study

Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study

... defined CTE research to ...between CTE and AD, understanding and differentiating the clin- ical symptoms, particularly in older adults, remains a significant challenge ...predict CTE pathology will ...

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Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel

Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel

... with CTE developed a progressive MND ...milder CTE at death (stages II and III), a reflection of their short- ened lifespan, whereas those who present with cognitive symptoms die with advanced CTE ...

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Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change

Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change

... In CTE and CTE/ADNC, neurofibrillary tangles (NFT), neuropil threads (NT), and dot-like grains (DLG) were distrib- uted either in upper cortex or across all ...in CTE and ...

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Cerebral Waste Accumulation and Glymphatic Clearance as Mechanisms of Human Neurological Diseases

Cerebral Waste Accumulation and Glymphatic Clearance as Mechanisms of Human Neurological Diseases

... and chronic traumatic encephalopathy ...both CTE and TLE: 1) Extracellular p-tau followed unidirectional, fluid-driven pathways that led toward the space bordering large (>100 µm diameter) ...

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Pathology of the superior colliculus in chronic traumatic encephalopathy

Pathology of the superior colliculus in chronic traumatic encephalopathy

... the frequency of contacts with blood vessel profiles were present in only one case.. However, three cases had 258[r] ...

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