Chronic Wasting Disease
Transmission and Adaptation of Chronic Wasting Disease to Hamsters and Transgenic Mice: Evidence for Strains
... Chronic wasting disease (CWD) is a transmissible spongi- form encephalopathy (TSE), or prion disease, that affects mule deer (Odocoileus hemionus), black-tailed deer (subspecies of Odocoileus ...
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Title: Chronic Wasting Disease: Evolution of Diagnostic Testing for a Naturally Occurring Prion
... Since chronic wasting disease (CWD) was first identified nearly 50 years ago in a captive mule deer herd in the Rocky Mountains of the United States, it has slowly spread across North America through ...
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Chronic Wasting Disease in Cervids: Implications for Prion Transmission to Humans and Other Animal Species
... Chronic wasting disease (CWD) is a TSE that affects cervids, including deer, elk, reindeer, sika deer, and ...CWD disease risk in cervids is evident from surveillance data; in 2000, CWD was ...
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Association analysis of PRNP gene region with chronic wasting disease in Rocky Mountain elk
... Background: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cervids including white-tailed (Odocoileus virginianus) and mule deer (Odocoileus hemionus), Rocky ...
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Pathways of Prion Spread during Early Chronic Wasting Disease in Deer
... with chronic wasting disease (CWD) prions by oral and nasal mucosal exposure, and stud- ies of early CWD pathogenesis have implicated pharyngeal lymphoid tissue as the earliest sites of prion ...
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Alteration of the Chronic Wasting Disease Species Barrier by In Vitro Prion Amplification
... Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cervids now detected in 19 states of the United States, three Canadian provinces, and South ...TSE disease ...
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Infectious Prions in the Pregnancy Microenvironment of Chronic Wasting Disease-Infected Reeves' Muntjac Deer
... Jakob disease (vCJD) carrier state (1 in 2,000 people) in the United Kingdom (15) and with the first report of chronic wasting disease (CWD) in Europe (16), mandate a thorough investigation of ...
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Risk behaviors in a rural community with a known point-source exposure to chronic wasting disease
... Background: The emergence and continuing spread of Chronic Wasting Disease (CWD) in cervids has now reached 14 U.S. states, two Canadian provinces, and South Korea, producing a potential for ...
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Experimental Transmission of the Chronic Wasting Disease Agent to Swine after Oral or Intracranial Inoculation
... ABSTRACT Chronic wasting disease (CWD) is a naturally occurring, fatal neurode- generative disease of ...for disease-associated prion protein (PrP Sc ) by Western blotting ...
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<p>Chronic Wasting Disease In Cervids: Prevalence, Impact And Management Strategies</p>
... Abstract: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects members of the cervidae ...the disease distribution continues to expand in North America ...
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Susceptibility of Domestic Cats to Chronic Wasting Disease
... by chronic wasting disease (CWD), we evaluated the susceptibility of the domestic cat (Felis catus) to CWD infection ...prion disease, including a stilted gait, weight loss, an- orexia, ...
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Assessment of Chronic Wasting Disease Prion Shedding in Deer Saliva with Occupancy Modeling
... for chronic wasting disease (CWD) ...in disease transmission and for ...of disease; (ii) the shedding propensity is influ- enced neither by sex nor by prion protein genotype at codon 96; ...
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B Cells and Platelets Harbor Prion Infectivity in the Blood of Deer Infected with Chronic Wasting Disease
... if chronic wasting disease (CWD) blood infectivity is associated with the cellular versus the cell-free/plasma fraction of blood and (ii) in particular if B-cell (MAb 2-104 ⴙ ), platelet (CD41/61 ⴙ ...
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Human prion protein sequence elements impede cross species chronic wasting disease transmission
... Chronic wasting disease (CWD) is a fatal prion disease of North American deer and elk and poses an unclear risk for transmission to ...
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Cell-Based Quantification of Chronic Wasting Disease Prions
... Cell-based measurement of prion infectivity is currently restricted to experimental strains of mouse-adapted scrapie. Having isolated cell cultures with susceptibility to prions from diseased elk, we describe a ...
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Chronic Wasting Disease (CWD) Susceptibility of Several North American Rodents That Are Sympatric with Cervid CWD Epidemics
... Chronic wasting disease (CWD) is a highly contagious always fatal neurodegenerative disease that is currently known to naturally infect only species of the deer family, ...of disease ...
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Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques
... ABSTRACT Chronic wasting disease (CWD) is a fatal prion disease that can infect deer, elk, and moose. CWD was first recognized in captive deer kept in wildlife facili- ties in Colorado from ...
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Insights into Chronic Wasting Disease and Bovine Spongiform Encephalopathy Species Barriers by Use of Real-Time Conversion
... Enciphering characteristics of cBSE and cBSE-derived pri- ons are conserved after transspecies transmission. cBSE and CWD are prion diseases that have been naturally passaged in their respective species (cattle and ...
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Chronic Wasting Disease: Current Assessment of Transmissibility
... Chronic wasting disease (CWD) is a prion disease of cervids characterized by clini- cal symptoms of progressive weight loss, abnormal behaviour and excessive ...
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First case of chronic wasting disease in Europe in a Norwegian free-ranging reindeer
... repetitive walking and hyperexcitability, followed by weight loss. Other signs are polydipsia/polyuria, hyper- salivation, grinding of the teeth, frequent regurgitation and difficulty swallowing. Secondary aspiration ...
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