Circular RNA (circRNA)
Circular RNA ATXN7 promotes the development of gastric cancer through sponging miR-4319 and regulating ENTPD4
... closed circular construction formed the feature of circRNAs ...lated circRNA hsa_circ_0000069 promotes colorectal cancer cell proliferation and metastasis ...more, circular RNA ciRS-7 is ...
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Translation of the circular RNA circβ catenin promotes liver cancer cell growth through activation of the Wnt pathway
... artificial circRNA can be translated independently of the IRES sequence [21, ...“non-coding RNA” actually has the protein-coding capacity and they are ...enriched circular RNA circ-ZNF609 was ...
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Circular RNA ABCB10 promotes hepatocellular carcinoma progression by increasing HMG20A expression by sponging miR-670-3p
... non-coding RNA family, circular RNA (circ RNA) is a closed circular ...Circ RNA has been reported to be involved in multiple processes of tumor progression, which provides a new ...
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<p>Circular RNA 0060745, a Novel circRNA, Promotes Colorectal Cancer Cell Proliferation and Metastasis Through miR-4736 Sponging</p>
... a circular RNA molecule with a 3 ʹ ,5 ʹ -phosphodiester bond at the junction ...36 Circular RNAs can modulate gene expression through modulation of transcription, pro- tein binding, sponging of ...
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Comparative Analysis of Gammaherpesvirus Circular RNA Repertoires: Conserved and Unique Viral Circular RNAs
... of circular RNAs containing the exon 2b-to-exon 1b backsplices, we designed exon 1b, 2a, and 2b leftward PCR primers and a common exon 2b rightward PCR primer ...a circular RNA containing exons 1b, ...
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Comprehensive circular RNA profiling reveals that circular RNA100783 is involved in chronic CD28-associated CD8(+)T cell ageing
... micro- RNA targets (Betel et al. 2010). Accordingly, for each circRNA exhibiting greater than a 2-fold expression level, we identified 5miRNAs with the highest mirSVR ...“Top-5-mi” circRNA-miRNA ...
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Circular RNA and tumor microenvironment
... TME, nourished by the vasculature, consists of the cell compartment (which includes tumor cells, immune cells, and other nonmalignant cells), extracellular matrix (ECM) and abundant signaling molecules. It is the ...
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Circular RNA profiling identified an abundant circular RNA circTMTC1 that inhibits chicken skeletal muscle satellite cell differentiation by sponging miR-128-3p
... of circRNA are still largely undetermined, but recent studies have shown that some circRNAs that are derived from exons of protein-coding genes can function as miRNA sponges ...
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Current prevalence status of gastric cancer and recent studies on the roles of circular RNAs and methods used to investigate circular RNAs
... While circular RNA (circRNA) is increasingly attracting attention from researchers, at the same time, its mystery has gradually been ...that circRNA can act as molecular sponge of miRNA to ...
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Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma
... the circRNA LRP6 negatively regulates the levels of KLF2 and APC to promote the development of OS ...the circular RNA circ_0001721 predicts unfavourable prognosis in OS and facilitates cell cycle ...
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Infrastructures of systems biology that facilitate functional genomic study in rice
... endogenous RNA; circRNA: Circular RNA; CREP: Collections of rice expression profiling database; CRISPR/ Cas9: clustered regularly interspaced short palindromic repeats-associated nuclease 9; ...
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A novel circulating hsa_circ_0081001 act as a potential biomarker for diagnosis and prognosis of osteosarcoma
... treatment. Circular RNA (circRNA) is a new type of endogenous noncoding RNA that could serve as ideal biomarkers in cancer because of its stable loop ...novel circRNA, hsa_circ_0081001, ...
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CircRNAs in cancer metabolism: a review
... endogenous RNA; circRNA: Circular RNA; CSC: Cancer stem cell; ESRP1: Epithelial-splicing regulatory protein 1; FA: Fatty acid; FAO: Fatty acid β -oxidation; FAS: Fatty acid synthesis; FASN: ...
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Identifying and Characterizing circRNA-Protein Interaction
... emerging circular RNAs may represent a great potential for theranostics. Circular RNAs play crucial roles in cell homeostasis and are involved in many disease phenotypes when there are ...of circular ...
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A circRNA–miRNA–mRNA network identification for exploring underlying pathogenesis and therapy strategy of hepatocellular carcinoma
... CircRNA: circular RNA; HCC: hepatocellular carcinoma; RT‑qPCR: reverse tran‑ scription‑quantitative polymerase chain reaction; CMap: connectivity map; ceRNA: competing endogenous RNA; MRE: ...
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CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis
... For circRNA study, total RNA was digested with Rnase R (Epicentre, Madison, the USA) to remove linear RNA and enrich circular ...enriched circRNA was amplified and transcribed into ...
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RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer
... special circular covalently bonded structure, circRNAs are resistant to exonucleases, which makes circRNAs more stable than linear RNA isoforms ...[2]. Circular RNA arises from ex- onic, ...
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Immune-related long non-coding RNA signature identified prognosis and immunotherapeutic efficiency in bladder cancer (BLCA)
... interval; circRNA: Circular RNA; DC: Dendritic cells; DCA: Decision curve analysis; CTLA-4: Cytotoxic T-lymphocyte-associated protein 4; EMT: Epithelial-mesenchymal transition; ESTIMATE: Estimation ...
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circRNA-miRNA-mRNA regulatory network in human lung cancer: an update
... non-coding RNA (lncRNA) and circular RNA (circRNA) are the top three members of ncRNAs in researches when search in the ...single-stranded circular transcripts with a 3 ′ –5 ′ cova- ...
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Circular RNAs in cancer: an emerging key player
... that RNA-binding proteins (RBPs), such as RNA polymerase II [8], Argonaute [3], and MBL [50], can bind to ...the circular RNA circ-Foxo3 repressed cell cycle pro- gression through binding to ...
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