Circular RNAs
<p>Emerging roles of circular RNAs in colorectal cancer</p>
... Abstract: Circular RNAs (circRNAs) are a newly discovered class of endogenous non- coding RNAs. Owing to the development of high-throughput sequencing, researchers have identi fi ed thousands of ...
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Circular RNAs: New Players in Gene Regulation
... Another area of potential future research interest is related to context-related changes in expression. A number of recent studies have proposed potential mechanisms concerning regulation of circRNA abundance. For exam- ...
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Circular RNAs in cancer: an emerging key player
... Noncoding RNAs (ncRNA) can be categorized into two subclasses, namely housekeeper ncRNAs (ribosomal RNA (rRNA), tRNA, small nuclear RNA (snRNA), snoRNA) and regulatory ...noncoding RNAs (<200 bp), which ...
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Synthesis of Infectious Viroids and Other Circular RNAs
... unencapsidated circular single-stranded RNAs of about 240-400 nucleotides with extensive internal base pairing resulting in rod-like secondary ...subviral circular RNAs that depend on helper ...
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Circular RNAs: analysis, expression and potential functions
... rapidly. Circular RNAs (circRNAs), the 3 ′ and 5 ′ ends of which are covalently linked, constitute a class of RNA recently discovered to be widespread and abundant (Salzman et ...
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Circular RNAs and their associations with breast cancer subtypes
... Circular RNAs (circRNAs) are highly stable forms of non-coding RNAs with diverse biological functions. They are implicated in modulation of gene expression thus affecting various cellular and disease ...
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Circular RNAs: emerging cancer biomarkers and targets
... Circular RNAs (circRNAs) are a class of RNA molecules that lack 5′-3′ ends and poly A tail and covalently form closed loops. Owing to this structure, circRNAs are not easily degraded by exonuclease RNase R ...
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The emerging roles and functions of circular RNAs and their generation
... Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5 ’ and 3 ’ termini are covalently linked by back-splicing of exons from a single ...
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Functions and Implications of Circular RNAs in Antiviral Immunity
... other RNAs including circular RNAs ...non-coding RNAs, long noncoding precisely; evidence of translations has been reported from these ...ing RNAs, cellular transports, transcriptional ...
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Circular RNAs in immune responses and immune diseases
... Circular RNAs (circRNAs) are novel clusters of endogenous noncoding RNAs (ncRNAs) that are widely expressed in eukaryotic ...their circular configurations, expression in blood and peripheral ...
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Novel insights into circular RNAs in clinical application of carcinomas
... Abstract: Circular RNAs (circRNAs), formed by nonsequential back-splicing of pre-messenger RNA (pre-mRNA) transcripts, have been widely concerned in recent ...
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Advances in circular RNAs and their roles in breast Cancer
... some circular RNAs could cis or trans regulate gene transcription ...tron circular RNAs can regulate parental gene transcrip- ...exon-intron circular RNAs, circ-EIF3J and ...
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Circulating and circular RNAs and the need for rationalization and synthesis of the research spiral
... – circular and circu- lating RNAs – and show how they are ...of circular RNAs, which are still quite obscured by the rapidly expanding body of knowledge in biology, have added another ...
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MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer
... Noncoding RNAs (ncRNAs) can be divided into microRNAs (miRNAs), long noncod- ing RNAs (lncRNAs), circular RNAs (circRNAs), pRNAs, and ...
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Comparative Analysis of Gammaherpesvirus Circular RNA Repertoires: Conserved and Unique Viral Circular RNAs
... identified circular RNAs (circRNAs) expressed from the Epstein-Barr virus (EBV) and Kaposi’s sarcoma herpesvirus (KSHV) human DNA tu- mor ...EBV circular RNAs circRPMS1_E4_E3a and ...
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An Emerging Role for Circular RNAs in Osteoarthritis
... Circular RNAs (circRNAs) are currently classed as non-coding RNAs that, unlike the better known canonical linear RNAs, form a covalently closed continuous loop without 5’ or 3’ ...
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Progress in research on the role of circular RNAs in lung cancer
... closed circular structure and high thermal stability ...years, circular RNAs were found to be stable and prevalent in a variety of species and tissues, with cell phenotype specificity and tissue de- ...
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Circular RNAs: a rising star in respiratory diseases
... as the name suggests, back-splicing happens first, and the two introns are paired with complementary motifs, and the 5′ splice donor and the 3′ splice acceptor are juxtaposed to generate EcircRNAs directly. In the exon ...
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Circular RNAs: biogenesis, expression and their potential roles in reproduction
... bound circular RNA molecule [3, ...interesting RNAs with a circular structure in the eukaryotic cytoplasm were identified using an elec- tron microscope ...these RNAs were only regarded as ...
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Circular RNAs: a new frontier for cancer diagnosis and therapy
... As a new type of competing endogenous RNA (ceRNA) that is widely believed to decoy relevant microRNAs (miR- NAs), circRNAs can impact the bio-functions of miRNAs and thus play an important role in the regulation of miRNA ...
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