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circulating tumor cells (CTC)

Characteristics of circulating tumor cells in organ metastases, prognosis, and T lymphocyte mediated immune response

Characteristics of circulating tumor cells in organ metastases, prognosis, and T lymphocyte mediated immune response

... Abstract: Circulating tumor cells (CTCs) possess profound influence on tumor metastases and disease ...T cells was ...mesenchymal circulating tumor cells (EMCTCs) ...

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Association of a novel circulating tumor DNA next generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer

Association of a novel circulating tumor DNA next generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer

... biopsies, circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), give insight into the “liquid phase” of solid tumors by provid- ing information on the spatial and temporal ...

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The viable circulating tumor cells with cancer stem cells feature, where is the way out?

The viable circulating tumor cells with cancer stem cells feature, where is the way out?

... stem cells (CSCs) became the research hotspot, emerging studies attempt to reveal the functions of these special subsets in ...needed. Circulating tumor cells (CTCs), as the method of ...

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Exploring Markov modeling approaches for the health economic assessment of circulating tumor cells in the management of metastatic prostate cancer patients

Exploring Markov modeling approaches for the health economic assessment of circulating tumor cells in the management of metastatic prostate cancer patients

... for Circulating Tumor Cells TheRapeutic APheresis, is a new method to improve the use of CTC’s in the clinical ...unused cells and fluids [40] (see figure ...

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Nanotechnology for the detection and kill of circulating tumor cells

Nanotechnology for the detection and kill of circulating tumor cells

... detect circulating tumor cells; it consists of solenoidal microcoils, a portable permanent magnet, and custom-built NMR ...then cells are in- cubated with monoclonal antibodies against the ...

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Technical challenges in the isolation and analysis of circulating tumor cells

Technical challenges in the isolation and analysis of circulating tumor cells

... cancer cells display dynamic molecular changes in response to systemic ...therapy. Circulating tumor cells (CTCs) in the peripheral blood represent a readily available source of cancer ...

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Does primary neoadjuvant systemic therapy eradicate minimal residual disease? Analysis of disseminated and circulating tumor cells before and after therapy

Does primary neoadjuvant systemic therapy eradicate minimal residual disease? Analysis of disseminated and circulating tumor cells before and after therapy

... by circulating tumor cells (CTCs), and to bone marrow (BM), reflected by disseminated tumor cells (DTCs) in up to 40 % of the patients [6, ...these cells have rarely been ...

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Clinical relevance and biology of circulating tumor cells

Clinical relevance and biology of circulating tumor cells

... of circulating tumor cells (CTCs) in peripheral blood and disseminated tumor cells (DTCs) in bone marrow of tumor patients has become an active area of translational cancer ...

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What's new on circulating tumor cells? A meeting report

What's new on circulating tumor cells? A meeting report

... Circulating tumor cells (CTCs) provide unique information for the management of cancer ...stem cells (CSCs) and the relevance of most recent fi ndings for the development of new targeted ...

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Circulating tumor cells and DNA as liquid biopsies

Circulating tumor cells and DNA as liquid biopsies

... end, circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) shed from primary and metastatic cancers may allow the non-invasive analysis of the evolution of tumor ...

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Microfluidics for antibody-independent separation of circulating tumor cells

Microfluidics for antibody-independent separation of circulating tumor cells

... Separation of circulating tumor cells (CTC) from the blood without using antibodies is a key challenge in the diagnosis of cancer. This article has reviewed few antibody-independent techniques ...

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Stemness Gene Profiles of Circulating Tumor Cells

Stemness Gene Profiles of Circulating Tumor Cells

... Circulating tumor cells (CTCs) are a population of tumor-derived cells that detach from the primary tumor and initiate ...cancer cells may be highly important in ...

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Circulating tumor cells (CTCs) in lung cancer: current status and future perspectives

Circulating tumor cells (CTCs) in lung cancer: current status and future perspectives

... prognosis. Circulating tumor cells (CTCs) are tumor cells that are shed from the primary site and circulate in the peripheral blood, and recent studies have shown that CTCs can be ...

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Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA

... (including circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA)), has emerged as a technique for the characterization of circulating cells, providing a strong ...

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Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer

Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer

... of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) emerging as “ liquid biopsies ” ...of ...

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Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy

<p>Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy</p>

... However, the role of CTCs in patients receiving NAC remains unclear. Several reports have indicated that CTC counts decreased after NAC in some patients, but increased in other patients. 16,17 A recent study observed an ...

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Evaluation of proliferation and apoptosis markers in circulating tumor cells of women with early breast cancer who are candidates for tumor dormancy

Evaluation of proliferation and apoptosis markers in circulating tumor cells of women with early breast cancer who are candidates for tumor dormancy

... Our study has several limitations that should be consid- ered. First, an overlap was observed in the detection of proliferation and apoptosis markers between the relapse- free DC and those who relapsed, representing a ...

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Circulating Tumor Cells: Moving Biological Insights into Detection

Circulating Tumor Cells: Moving Biological Insights into Detection

... a tumor is diagnosed [23, 26], indicating the potential of CTCs as a diagnostic parameter of early disease [11-13, ...cancer cells in the primary tumor are able to metastasize to different organs and ...

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Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemo- radiation therapy

Circulating tumor cells: A promising marker of predicting tumor response in rectal cancer patients receiving neoadjuvant chemo- radiation therapy

... hematologic cells (7-10μm in diameter) [23], more and more methods based on the differences of cell sizes are used for CTC detection and their capture rates of CTCs are much higher than those using immunomagnetic ...

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Detection of circulating tumor cells by p75NTR expression in patients with esophageal cancer

Detection of circulating tumor cells by p75NTR expression in patients with esophageal cancer

... The proportion of EpCAM + p75NTR+ cells in EpCAM+ cells (average ± SD) was 56.7 ± 39.6 % (range 5.6–100.0 %). Based on the ROC curve analysis to differ- entiate ESCC patients from controls, the largest AUC ...

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