CISPLATIN INDUCED NEPHROTOXICITY
Mechanisms Underlying Cisplatin Induced Nephrotoxicity- A Review
... carcinoma. Cisplatin induced nephrotoxicity is a challenging side effect during ...kidneys, cisplatin preferentially accumulates in renal tubular cells causing tubular cell injury and death, ...
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COENZYME Q10 AMELORATES CISPLATIN-INDUCED NEPHROTOXICITY IN RATS
... Cisplatin-induced nephrotoxicity was indicated by significant increases in both serum urea nitrogen and renal tissue interleukin-18 (a marker of ...reversed cisplatin-induced ...
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Protective Effects of Molsidomine Against Cisplatin-Induced Nephrotoxicity
... including cisplatin, used in the treatment of various diseases could lead to deleterious effects, especially on the kidney and nervous system [2–4, ...31–33]. Cisplatin accumulates in the proximal tu- bular ...
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Amelioration of Cisplatin - Induced Nephrotoxicity by Roots of Anthocephalus Cadamba
... w. Nephrotoxicity was induced by injecting cisplatin (5 mg/kg ...attenuated nephrotoxicity induced by cisplatin which was confirmed by reducing levels of serum markers, urinary ...
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Cisplatin Induced Nephrotoxicity- An Assessment Based on Calculated Creatinine Clearance
... of cisplatin induced ...of nephrotoxicity was high in male patients in other ...with nephrotoxicity, it may be due to inclusion of pelvic Malignancy cases in our ...
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ALLEVIATION OF CISPLATIN INDUCED NEPHROTOXICITY IN ALBINO RATS BY ROOTS OF Catunaregam uliginosa
... received cisplatin exhibited a significant increase in serum marker levels, increased U TP excretion, and reduced ...effects induced by cisplatin in a dose-dependent manner in both curative and ...
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Prophylactic Effect of Butea monosperma against Cisplatin-Induced Nephrotoxicity in Rats
... ABSTRACT Cisplatin is an effective chemotherapeutic agent for solid tumors; however its use is limited by ...in cisplatin-induced nephrotoxicity and oxidative stress in ...only ...
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Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats
... of cisplatin [3]. The accumulation of high concentrations of cisplatin in the kidneys caused nephrotoxicity ...[5]. Cisplatin-induced nephrotoxicity through apoptosis and ...
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Protective properties of dietary inclusion of Ocimum sanctum on cisplatin-induced nephrotoxicity in rats
... Background: Nephrotoxicity is a frequent severe side effect of cisplatin chemotherapy, limiting its clinical use despite being one of the most potent chemotherapy ...against cisplatin-induced ...
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Study the Nephroprotective Effect of Ziziphus Jujube Extract Against Cisplatin -Induced Nephrotoxicity
... radicals. Cisplatin is an anticancer agent used largely in treatment of solid ...of cisplatin is ...on cisplatin-induced ...received cisplatin at 5mg/kg, group III received ZE at ...
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Effect of the ethanolic extract of Scoparia dulcis in cisplatin induced nephrotoxicity in wistar rats
... against cisplatin induced nephrotoxicity in Wistar ...Methods: Nephrotoxicity was induced by a single intra-peritoneal administration of Cisplatin (6 mg/kg) in wistar ...control. ...
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NEPHROPROTECTIVE ACTIVITY OF CYANOTIS FASCICULATA VAR., FASCICULATA AGAINST CISPLATIN INDUCED NEPHROTOXICITY
... During in-vitro studies for antioxidant activity the CFEE exhibited an appreciable ‘NO’ scavenging ability, which is an important contributing factor in Cisplatin induced nephrotoxicity. In addition, ...
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Effect of Vernonia cinerea Aerial Parts Against Cisplatin-induced Nephrotoxicity in Rats
... the cisplatin induced renal ...in cisplatin-induced nephrotoxicity might be attributed to the presence of different phytochemical constituents in these extracts and also probably due to ...
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The Renoprotective Effect of Methanolic Extract of Portulaca Oleracea on Cisplatin-Induced Nephrotoxicity in Wistar Rats
... DISCUSSION This study investigated the possible renoprotective effect of orally administered methanolic extract of portulaca oleracea on cisplatin induced nephrotoxicity in wistar rats. The study was ...
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Original Article Risk analysis for cisplatin-induced nephrotoxicity during first cycle of chemotherapy
... Although cisplatin is one of the most widely used anticancer drugs, nephrotoxicity remains a major dose- limiting side ...of cisplatin-induced nephrotoxicity, we analyzed possible risk ...
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Cisplatin-Induced Nephrotoxicity in Rats: Modulatory Role of Simvastatin and Rosuvastatin against Apoptosis and Inflammation
... in cisplatin-induced nephrotoxicity in ...Acute nephrotoxicity was induced in rats by single injection of cisplatin on the 10th day of the treatment ...to cisplatin ...
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Imaging of reactive oxygen species using [3H]hydromethidine in mice with cisplatin-induced nephrotoxicity
... accumulated cisplatin leads to nuclear and mitochondrial DNA damage and ROS production, followed by activation of necrotic and apoptotic pathways ...between cisplatin- induced nephrotoxicity ...
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Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway
... single cisplatin injection in ...of cisplatin-induced oxidative stress in the kidney with melatonin ...attenuates cisplatin-induced nephrotoxicity in rats by modulating Nrf2/HO-1 ...
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IN-VITRO NEPHROPROTECTIVE ROLE OF ETHANOLIC ROOT EXTRACT OF Boerhaavia diffusa AGAINST CISPLATIN-INDUCED NEPHROTOXICITY
... on cisplatin induced nephrotoxicity Cisplatin, an antineoplastic drug accumulates in the proximal tubular region of the kidney induces nephrotoxicity and undergoes metabolic activation ...
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A glance at molecular mechanisms underlying cisplatin-induced nephrotoxicity and possible renoprotective strategies: a narrative review
... in cisplatin-induced ...that cisplatin depletes glutathione (GSH) storage in the ...in cisplatin resulted in a marked decrease by 33% in GSH after 15 min and a peak decrease of 27% (normal ...
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