Class I human leukocyte antigen
Proline 78 Is Crucial for Human Immunodeficiency Virus Type 1 Nef To Down-Regulate Class I Human Leukocyte Antigen
... Our results showed that Pro78 was the most critical residue for HLA-I down-regulation, while Pro72 and Pro75 were much less critical. Since the latter proline residues have been shown to form an SH3-binding ...
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THE PROFILE OF HUMAN LEUKOCYTE ANTIGEN CLASS I IN PATIENTS WITH SCHIZOPHRENIA
... of Human Leukocyte Antigen (HLA) class 1 (A&B) alleles in the selected sample of schizophrenic patients in Iraqi ...One human leukocyte antigen -A gene (A*03) and two ...
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Investigation of Human Leukocyte Antigen (HLA) Class I and II Alleles and Hepatitis C Virus (HCV) Genotypes in Patients Infected with HCV
... HLA class I and class II genotypes analysis in healthy controls demonstrated that the most frequent alleles were DQ6 31%, DQ2 ...the class II alleles, HLA-DRB1*03, and HLA-DRB1*10 were ...
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Human Leukocyte Antigen Variants B*44 and B*57 Are Consistently Favorable during Two Distinct Phases of Primary HIV-1 Infection in Sub-Saharan Africans with Several Viral Subtypes
... We and others have reported previously that both host and viral factors can independently impact HIV-1 VL during the early and chronic phases of infection (54, 81, 84, 85). Host factors ranged from coreceptor gene (e.g., ...
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Human Leukocyte Antigen-C Class I Population -Based Ancestry Of Genetic Ethnic Diversity In Nigeria
... HLA class I and II genes has not only provided a clear picture of the molecular basis of allelic polymorphism, but also allowed the development of a variety of PCR-based DNA typing ...
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Splice acceptor site mutation of the transporter associated with antigen processing 1 gene in human bare lymphocyte syndrome
... Histocompatibility leukocyte antigen (HLA) class I mol- ecules present peptides derived from intracellular pro- teins to cytotoxic T ...with class I heavy chains (HCs), which ...
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The Human Leukocyte Antigen (HLA) DRB1*13:02 Allele Protects against Dementia in Continental Western Europe
... namely Class I (A, B, C) and Class II (DRB, DQB, DPB), facilitate immune protection from harmful antigens via presentation of endogenous antigenic peptides to CD8 receptors to signal cell destruction ...
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Human leukocyte antigen class I, class II, and tumor necrosis factor-alpha polymorphisms in a healthy elder Mexican Mestizo population
... Longevity studies must ideally include healthy centenari- ans, as they represent the extreme of human old age. Most studies carried out on centenarians come from either Europe or Asiatic countries such as Japan. ...
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Involvement of human leukocyte antigen class I molecules in human immunodeficiency virus infection of CD4-positive cells.
... Questioning the exact roles of virus-associated MHC-I molecules and cell surface-expressed MHC-I molecules during the HIV life cycle became urgent, particularly in light of the debate su[r] ...
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Activities of stromal and immune cells in HPV-related cancers
... HLA: Human leukocyte antigen; HLA-DR: Human leukocyte antigen D related; HNSCC: Head and neck squamous cell carcinoma; HPV: Human Papillomavirus; hrHPV: High risk HPV; ...
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Human leukocyte antigen class I and class II alleles are associated with susceptibility and resistance in borderline leprosy patients from Southeast Brazil
... HLA class II molecules have been consistently found to be associ- ated with different clinical phenotypes and disease per ...HLA class I initially did not consider the possibility that presentation ...
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Evolution of the levels of human leukocyte antigen G (HLA G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis
... HLA class I antigen, is of crucial interest during pregnancy by inhibiting mater‑ nal immune ...latent class analysis was used to test whether distinct sub‑populations of children, each with ...
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Human Leukocyte Antigen Class I Supertypes and HIV-1 Control in African Americans
... of human leukocyte antigen (HLA) class I supertypes in controlling human immunodeficiency virus type 1 (HIV-1) infection in African Americans has not been ...individual ...
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Association between human leukocyte antigen class II and pulmonary tuberculosis due to mycobacterium tuberculosis in Uganda
... they i) had a previous history suggestive of TB ii) previous diagnostic evaluation suggestive of TB iii) prior treatment suggestive of TB iv) symptoms and signs suggestive of TB (cough > 3 weeks, weight loss, ...
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Multiple immunofluorescence assay identifies upregulation of Active β catenin in prostate cancer
... responsible for the regulation of the immune system in humans (human leukocyte antigen class I). HLA-1 down- regulation is associated with stemness in multiple cancer types [9]. ...
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Targeting Swine Leukocyte Antigen Class I Molecules for Proteasomal Degradation by the nsp1α Replicase Protein of the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Strain JXwn06
... PRRSV has been reported to be capable of inducing apoptosis of PAMs (39, 40). To test whether this mechanism also contributes to the degradation of SLA-I molecules, mock- and PRRSV-in- fected PAMs were treated ...
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Respiratory Infections and the Risk of Celiac Disease
... recruited, and human leukocyte antigen DQ2- or DQ8-positive infants were followed up with clinical and serological evaluations. Cross tabulation and odds ratios were used to explore the risk ...
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The relationship between human leukocyte antigen DP/DQ gene polymorphisms and the outcomes of HCV infection in a Chinese population
... HLA class II molecules ...HLA class II-restricted epitopes goes unrecognized by T-cells may be one of the possible mechanisms of HCV to avoid immune clear- ance ...
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The biomarkers of immune dysregulation and inflammation response in Parkinson disease
... HLA, Human leukocyte antigen; JNK-STAT, Janus kinase/signal transducers and activators of transcription; LMP2, Large multifunctional protease 2; LMP7, Large multifunctional protease 7; LRRK2, ...
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A Study of Human Leukocyte D Locus Related Antigens in Graves' Disease
... unrelated controls and 41 patients with Graves' disease were typed for seven HLA DRw specificities. 28 patients with Graves' disease (68%) were positive for DRw3, in contrast to 14 controls (28%); whereas only 21 ...
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