Class II MHC protein
The interaction of invariant chain-derived peptides (CLIP) with mouse class II MHC molecules
... CD4 complementary DNA complete Freund's adjuvant class II MHC transactivator protein class II MHC- containing vesicle class II MHC- associated invariant chain peptides deionised distille[r] ...
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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes
... type II trans- membrane proteins resembling C-type lectins, for which there is accumulating evidence to support crucial roles in the innate im- mune system (36, ...lectin protein with high similarity with ...
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The systems biology of MHC class II antigen presentation
... high MHC-II ...finger protein 1 (PRDM1) and B-lymphocyte-induced maturation protein 1 (BLIMP1) that inhibits CIITA transcription [18] (Figure ...the MHC-II transcription factor ...
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The involvement of heat shock protein molecular chaperones in MHC class II antigen processing and presentation
... to MHC class II molecules has been extensively studied ...of class II and characteristics placing it in the endolysosomal chain, such a compartment should possess HLA-DM molecules for ...
216
Presentation of intracellular antigen with MHC class II molecules
... The effect of am m onium chloride raises the possibility - given its reported effect on protein catabolism - that M(}) norm ally degrade C5 epitopes before they have the o p p o rtu n ity to bind w ith MHC ...
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A Novel Predictive Technique for the MHC Class II Peptide-Binding Interaction
... the MHC molecule and the bound peptide was analyzed using the anal program ...the MHC Class II binding interaction, it is necessary to provide some means of comparisons to the experi- mental ...
6
Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4+ T Cells
... maintenance protein LANA, which is expressed in all KSHV-infected cells and malignancies, making it an attractive immunological ...maintenance protein homologue in EBV, EBNA1, LANA includes extensive repeat ...
11
Cytotoxic T lymphocyte responses to Ras protein
... reduced class II MHC on their cell surface (365, ...p21Ras protein as murine leukemia virus (MLV) lacking the Ki-ras gene, did not cause reduced cell surface class II expression ...
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Association of CD99 short and long forms with MHC class I, MHC class II and tetraspanin CD81 and recruitment into immunological synapses
... and protein segregation, signaling compartmentali- zation, and bidirectional information exchange through soluble and membrane-bound transmitters ...including MHC and tetraspanin CD81, have been shown to ...
13
Induction of CD4-Independent E7-Specific CD8+ Memory Response by Heat Shock Fusion Protein
... as protein chaperones, are highly immunogenic and play a fundamental role in immune surveillance of infection and ma- lignancy (27, 33, ...fusion protein composed of Mycobacterium bovis BCG Hsp65 linked to ...
11
Novel epitope based peptides for vaccine against SARS-CoV-2 virus: immunoinformatics with docking approach
... S protein that can serve as vaccine ...10 MHC class I binding T-cell peptides and 6 MHC class II binding T- cell peptides that are all conserved potential epitopes that might ...
10
Tumor-specific CD4 T cells eradicate myeloma cells genetically deficient in MHC class II display
... myeloma protein [20, ...constitutive MHC II expression, MOPC315 cells may start to express MHC class II under certain in vivo conditions, as observed for the B16 melanoma [1, ...
8
Sex-dependent treatment of chronic EAE with partial MHC class II constructs
... partial MHC class II constructs have been described elsewhere [15, ...For protein pro- duction, 4 L of Luria-Bertani medium, supplemented with 50 μg/ml of carbenicillin, was inoculated with a ...
11
Interactions of the transcription factors MIBP1 and RFX1 with the EP element of the hepatitis B virus enhancer.
... of protein binding between the EP or EF-C site and the MHC class II X-box sequence and concluded that proteins bound the viral EP and EF-C sites with a higher affinity than the MHC ...
7
IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments
... Control and IFN-γ-activated astrocytes growing on cov- erslips were fixed in 2% paraformaldehyde for 5 min at room temperature and treated with 10% goat serum for 1 h at 37°C. In some experiments, astrocytes were incu- ...
13
Footprints of antigen processing boost MHC class II natural ligand predictions
... of MHC peptide binding predic- tions and/or in vitro binding ...the MHC-II binding core of the validated ...source protein using the EL or EL + context ...source protein into ...
15
Evolution of MHC Class II Eβ Diversity Within the Genus Peromyscus
... the MHC has been a contentious ...of class II recombination can generate novel sequences with po- genes (Richman et ...the MHC, including demogra- the predominant source of allelic ...
10
Blocking MHC class II on human endothelium mitigates acute rejection
... To analyze T lymphocytes, cells were collected after isolation or mixed EC-lymphocyte cocultures, washed in 1× PBS, and stained in FACS-staining buffer (PBS/1% BSA) with eFluor 450 fixable viability dye (eBioscience), ...
17
Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse
... family such as the MHC (Ellis et al. 1995; Fraser and The five positions in the 6 Przewalski’s horse sequences Bailey 1996). We established a possible explanation for that showed synonymous variation and the 11 ...
10
Mannosylated T/Tn with Freund’s adjuvant induces cellular immunity
... Inducing cancer-specific cellular immune responses has become an attractive strategy in cancer treatment. In this study, we investigated the role of several adjuvants in eliciting T/Tn-specific cellular immunity and ...
15