Classical swine fever virus
Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway
... ABSTRACT Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), which poses a serious threat to the global pig ...
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N-Linked Glycosylation Status of Classical Swine Fever Virus Strain Brescia E2 Glycoprotein Influences Virulence in Swine
... of classical swine fever virus ...including virus attachment and entry to target cells, production of antibodies, induction of protective immune response in swine, and ...of ...
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Mutations Abrogating the RNase Activity in Glycoprotein Erns of the Pestivirus Classical Swine Fever Virus Lead to Virus Attenuation
... four virus species has been proposed that is based on the results of sequence com- parison studies and takes into account that pestiviruses infect different host ...diarrhea virus and border disease ...32). ...
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Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins.
... of classical swine fever virus (CSFV) are able to confer protective immunity in swine, N-terminal autoprotease, viral core protein, and the three structural glycoproteins were expressed ...
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Cytopathogenicity of Classical Swine Fever Virus Correlates with Attenuation in the Natural Host
... pathogens classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV), cytopathogenic (cp) and non-cp viruses are distinguished according to the induction of apoptosis in ...
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Clustering of classical swine fever virus isolates by codon pair bias
... Classical swine fever (CSF) is a serious and highly conta- gious disease of pigs that can cause important econom- ical losses in the pig industries ...the classical swine fever ...
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Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine
... parental virus infec- tions, with an increased accumulation of E2 homodimers over E1-E2 heterodimers while proportions of E2 monomers re- mained ...(CSFV, classical swine fever virus; ...
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A Recombinant Classical Swine Fever Virus Stably Expresses a Marker Gene
... Classical swine fever virus (CSFV) is a small, enveloped vi- rus with a positive-stranded RNA genome ...rhea virus (BVDV) and border disease virus, CSFV forms the genus ...
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The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine
... of classical swine fever virus (CSFV) virulence and host range, chimeras of the highly pathogenic Brescia strain and the attenuated vaccine strain CS were constructed and evaluated for viral ...
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Characterization of Helper Virus-Independent Cytopathogenic Classical Swine Fever Virus Generated by an In Vivo RNA Recombination System
... diarrhea virus (BVDV), cp classical swine fever virus (CSFV) field isolates were rarely detected and always represented helper virus- dependent ...helper virus-independent ...
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Mutations in Classical Swine Fever Virus NS4B Affect Virulence in Swine
... of classical swine fever virus (CSFV), the etiological agent of a severe, highly lethal disease of ...in swine macrophages, including a significant sustained accumulation of ...
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Discovering up-regulated VEGF–C expression in swine umbilical vein endothelial cells by classical swine fever virus Shimen
... Classical swine fever (CSF) is a serious swine disease that occurs in most developed countries, including China, which seriously affects the economic development of the pig-breeding industry ...
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Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins
... Proteolytic processing of polyproteins is considered a crucial step in the life cycle of most positive-strand RNA viruses. An enhancement of NS2-3 processing has been described as a major difference between the ...
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Classical swine fever virus NS5A protein changed inflammatory cytokine secretion in porcine alveolar macrophages by inhibiting the NF κB signaling pathway
... CSFV, Classical swine fever virus; ECL, Enhanced chemiluminescence; ELISAs, Enzyme-linked immunosorbent assays; FBS, Fetal bovine serum; HCV, Hepatitis C virus; IRF3, IFN-regulatory ...
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In vitroinfection with classical swine fever virus inhibits the transcription of immune response genes
... Classical swine fever (CSF) is a devastating disease, which is responsible for substantial economic losses due to the death of valuable ...reason, classical swine fever ...
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The Laminin Receptor Is a Cellular Attachment Receptor for Classical Swine Fever Virus
... FIG 2 LamR is required for CSFV infection. (A) Reduced LamR expression following the knockdown of LamR expression by siRNA. PK-15 cells were transfected with siLamR or siScr, treated only with the transfection reagent ...
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Characterization of Essential Domains and Plasticity of the Classical Swine Fever Virus Core Protein
... The consequences of the above-described flexibility and plasticity of the Core protein for the size and shape of CSFV particles are currently not known. Pestiviruses are exceedingly difficult to purify from cellular ...
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Cytopathogenicity of classical swine fever virus caused by defective interfering particles.
... For further analysis of the transfection experiment, RNA was prepared and analyzed by Northern hybridization. When RNA from cells infected with noncp CSFV Alfort was used for transfection of noninfected target cells, ...
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Proteomic analysis of swine serum following highly virulent classical swine fever virus infection
... Here, we report a proteomic analysis of serum protein profile of CSFV-infected pigs and uninfected controls, in which the alterations of protein expression in CSFV- infected pig serum were characterized by two-dimension ...
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Porcine Viperin protein inhibits the replication of classical swine fever virus (CSFV) in vitro
... A virus, Viperin targeted lipid rafts to interfere virus re- lease from the plasma membrane of infected cells ...influence virus release. And virus binding/entry examination indicated the ...
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