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Clinical oncology

Advancing clinical oncology through genome biology and technology

Advancing clinical oncology through genome biology and technology

... Clinical oncology - facing up to the next steps More than any other field of medicine, oncology has bene- fited from recent revolutionary advances in nucleic acid sequencing technology and genomic ...

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Monitoring cancer stem cells: insights into clinical oncology

Monitoring cancer stem cells: insights into clinical oncology

... in clinical oncology as CSC populations may reflect true treatment response and assist with managing treatment strategies, such as defining optimal chemotherapy cycles, permit- ting pretreatment cancer ...

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J Clin Oncol 22: by American Society of Clinical Oncology INTRODUCTION

J Clin Oncol 22: by American Society of Clinical Oncology INTRODUCTION

... Randomized clinical trials have shown that prophylactic CSF can reduce the risk of neutropenic complications 6,23-25 and facilitate the deliv- ery of full ...

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Trial Reporting in Immuno-Oncology (TRIO): An American Society of Clinical Oncology-Society for Immunotherapy of Cancer Statement

Trial Reporting in Immuno-Oncology (TRIO): An American Society of Clinical Oncology-Society for Immunotherapy of Cancer Statement

... Response Evaluation Criteria in Solid Tumors (RECIST) are used to evaluate antitumor activity of oncology drugs in most clinical trials, including most IO trials [10]. These criteria were developed for ...

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A systems approach to clinical oncology: Focus on breast cancer

A systems approach to clinical oncology: Focus on breast cancer

... randomized clinical trial, MINDACT, for LN-negative breast cancer, powered to look at the utility in clinical practice of the Amsterdam 70-gene prognostic sig- ...the clinical value of this new ...

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Integrating next-generation sequencing into clinical oncology: strategies, promises and pitfalls

Integrating next-generation sequencing into clinical oncology: strategies, promises and pitfalls

... routine clinical use, whereas additional data may be used for research and released on request to ...precision oncology lies in the detailed molecular characterisation of a large number of patients, and a ...

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Updates in Gastrointestinal Oncology – insights from the 2008 44th annual meeting of the American Society of Clinical Oncology

Updates in Gastrointestinal Oncology – insights from the 2008 44th annual meeting of the American Society of Clinical Oncology

... five clinical trials randomiz- ing patients with stage II and III colon cancer to either 5- FU based adjuvant chemotherapy or no post-operative treatment ...Cooperative Oncology Group (ECOG) 5202 study is a ...

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Clinical Oncology Journals | Cancer Research |High Impact Factor

Clinical Oncology Journals | Cancer Research |High Impact Factor

... Nowdays there are highly sensitive immunological methods and extensive experience was accumulated in DTC detection. The possibility of quantitative detection of DTCs and their phenotypic characteristics were established ...

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A Review of Modeling Approaches to Predict Drug Response in Clinical Oncology

A Review of Modeling Approaches to Predict Drug Response in Clinical Oncology

... Fig. 1 depicts a model-based framework for oncology drug de- velopment. First, a PK model is developed to describe the rela- tionship between dose and PK metrics, such as trough concen- tration, area under ...

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150 th Course Geriatrics, Molecular and Clinical Oncology: an Overwiew

150 th Course Geriatrics, Molecular and Clinical Oncology: an Overwiew

... Oncology Geriatrics a good opportunity to enlarge there knowledge, in t he s p le nd id f ram e of Er ic e ’s ph en ic ia n ol d c o un tr y, nam ed the world over as “City of Science, at the Ettore Majorana ...

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The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer

The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer

... • Neoadjuvant chemoradiotherapy + surgery + adju- vant chemotherapy was proven successful in the clin- ical studies of EGJ adenocarcinoma. However, scien- tific-based evidence for its therapeutic benefits on tumors at ...

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Recent advances in gastrointestinal oncology - updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology

Recent advances in gastrointestinal oncology - updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology

... Southwest Oncology Group S0356 study demonstrated that oxaliplatin is safe in the neoad- juvant setting and may potentially replace cisplatin when given with concurrent 5-FU and radiation ...

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Redacted Protocol for Journal of Clinical Oncology

Redacted Protocol for Journal of Clinical Oncology

... chemotherapy with pemetrexed and cisplatin. Patients who have a documented (confirmed or unconfirmed) response of CR, PR, or SD after completion of induction chemotherapy and have an Eastern Cooperative Oncology ...

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Economic Evaluation of Potential Applications of Gene Expression Profiling in Clinical Oncology

Economic Evaluation of Potential Applications of Gene Expression Profiling in Clinical Oncology

... current clinical practice (CCP) in post-menopausal women with estrogen- or progesterone-receptor-positive (ER+ or PR+), one to three positive axillary lymph-node (1-3 LN+), ESBC from the perspective of the ...

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J Clin Oncol 24: by American Society of Clinical Oncology INTRODUCTION

J Clin Oncol 24: by American Society of Clinical Oncology INTRODUCTION

... A total of 457 patients (DCF ⫽ 227; CF ⫽ 230) were randomly assigned from 72 centers in 16 countries between November 1999 and January 2003; 445 patients (DCF ⫽ 221; CF ⫽ 224) received the allocated combination and, ...

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J Clin Oncol 25: by American Society of Clinical Oncology INTRODUCTION

J Clin Oncol 25: by American Society of Clinical Oncology INTRODUCTION

... The recommendation for bone marrow response is that histolog- ically normal bone marrows with a small ( ⬍ 2%) clonal B-cell popu- lation detected by flow cytometry should be considered normal, given that definitive ...

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MOLECULAR AND CLINICAL ONCOLOGY 14: 44, 2021

MOLECULAR AND CLINICAL ONCOLOGY 14: 44, 2021

... Absence of meaningful neurocognitive recovery in comatose patients with primary central nervous system lymphoma despite an effective response to chemotherapy: Case reports.. RYAN MAO H[r] ...

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The most important questions in cancer research and clinical oncology

The most important questions in cancer research and clinical oncology

... or clinical infections. HPV-associated clinical infections include genital warts, skin warts, recurrent respiratory papillomatosis, squa- mous intraepithelial lesions and cervical ...

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Tumor Markers in Clinical and Diagnostic Oncology - Revisited

Tumor Markers in Clinical and Diagnostic Oncology - Revisited

... in clinical practice needs a thorough understanding of the basics of pathophysiology, techniques of identification or testing, reasons for out-of-range levels of tumor markers, as well as the knowledge of evidence ...

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Palliative Oncology Treatments and Hopelessness: An Analysis of Associated Clinical and Psychosocial Factors

Palliative Oncology Treatments and Hopelessness: An Analysis of Associated Clinical and Psychosocial Factors

... Results: The relative absence of information about palliative care treatment was associated with hopelessness after the beginning the palliative treatment (p=0.043). With regard to coping strategies, the use of social ...

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