Clinically isolated syndrome
Early predictors of conversion in patients with clinically isolated syndrome: a preliminary Egyptian study
... CDMS: Clinically definite multiple sclerosis; CIS: Clinically isolated syndrome; CNS: Central nervous system; CSF: Cerebrospinal fluid; EDSS: Expanded Disability Status Scale; Gd: Gadolinium; ...
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Peripheral blood lymphocytes immunophenotyping predicts disease activity in clinically isolated syndrome patients
... Clinically isolated syndrome (CIS) is the first manifest- ation of multiple sclerosis (MS), a chronic inflammatory autoimmune disease of the central nervous system (CNS) affecting over ...the ...
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Subcortical and Cortical Gray Matter Atrophy in a Large Sample of Patients with Clinically Isolated Syndrome and Early Relapsing Remitting Multiple Sclerosis
... Disclosures: Robert Zivadinov—RELATED: Grant: Biogen Idec;* UNRELATED: Consultancy: Teva Neuroscience,* Biogen Idec,* EMD Serono,* Questcor Pharmaceuticals,* Grants/ Grants Pending: Biogen Idec, Teva Neuroscience, ...
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Longitudinal Mixed Effect Model Analysis of the Association between Global and Tissue Specific Brain Atrophy and Lesion Accumulation in Patients with Clinically Isolated Syndrome
... with clinically isolated syndrome, the average whole-brain volume decreased ...with clinically isolated syndrome who showed greater percentages of change in whole-brain, white ...
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Short and long term clinical outcomes of use of beta interferon or glatiramer acetate for people with clinically isolated syndrome : a systematic review of randomised controlled trials and network meta analysis
... as clinically isolated syndrome (CIS) ...are isolated events of symptomatic neurological disturbance lasting more than 24 h, which indicate the first clinical demyelination of the central ...
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The Prognostic Utility of MRI in Clinically Isolated Syndrome: A Literature Review
... with clinically isolated syndrome, the treating clinician needs to advise the patient on the probability of conversion to clinically definite multiple ...with clinically isolated ...
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Trichuris suis ova in relapsing remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial
... or clinically isolated syndrome with clinical activity, not undergoing any standard therapies, will be randomized 1:1 to Trichuris suis ova 2,500 eggs every two weeks or matching ...
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Phase White Matter Signal Abnormalities in Patients with Clinically Isolated Syndrome and Other Neurologic Disorders
... with clinically isolated syndrome had significantly more phase and T2 WM signal abnormalities than healthy controls (P ⬍ ...with clinically isolated syndrome compared with ...
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A clinically isolated syndrome: butterfly glioma mimic
... The report explores a unique and treatable “butterfly”‑glioma mimic and the neuroimaging characteristics that help to diagnose this entity. A 35‑year‑old patient presented with subacute‑onset, progressive frontal lobe ...
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Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis
... with clinically isolated syndromes (CIS), mag- netic resonance imaging (MRI) abnormalities and the presence of immunoglobulin G (IgG) oligoclonal bands in cerebrospinal fluid (CSF) are important predictors ...
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Iron Deposition on SWI Filtered Phase in the Subcortical Deep Gray Matter of Patients with Clinically Isolated Syndrome May Precede Structure Specific Atrophy
... However, we believe that by using a large sample, and data both on abnormal phase and atrophy measures, our study provides support for the concept that iron deposition is pres- ent at the earliest MS disease stages and ...
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Improved Precision of Automatic Brain Volume Measurements in Patients with Clinically Isolated Syndrome and Multiple Sclerosis Using Edema Correction
... Disease-modifying immunomodulatory treatment options in MS vary in efficacy and adverse effect profile. Personalized treatment for a patient with MS requires clinically feasible and reliable as- sessment of ...
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MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome
... Methods: Four hundred and sixty-eight patients with a first episode suggestive of MS were classified as clinically mono- or multifocal by two neurologists blinded to magnetic resonance imaging (MRI) results. These ...
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Diffusion Tensor Group Tractography of the Corpus Callosum in Clinically Isolated Syndrome
... In our study, we observed that the CC regional FA was heterogeneous in healthy controls and patients with CIS: FAsplenium ⬎ FAgenu ⬎ FAbody, which has also been observed in other studies[r] ...
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Clinically and Radiological isolated syndrome (MS risk)
... Background: The use of brain magnetic resonance imaging (MRI) for evaluation of neurological disorders has increased in the past two decades. This has led to an increased detection of incidental fi ndings on brain MRI. ...
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Magnetic resonance imaging in the study of clinically isolated syndromes suggestive of multiple sclerosis
... New MRI activity (T2 and contrast-enhancing lesions), indicating dissemination of disease in time, was found to occur more frequently than clinical attacks, in keeping with the observation in established MS that MRI is a ...
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Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study
... In addition, the lack of consistent findings concerning the etiology, pathophysiology and risk factors for CFS reflects lack of standardized reproducible diagnostic criteria for CFS. CFS is defined as persistent or ...
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Random amplified polymorphic DNA analysis of clinically and environmentally isolated Cryptococcus neoformans in Nagasaki
... We examined clinical (pulmonary cryptococcosis and cryptococcal meningitis) and environmental (pigeon excreta) isolates of Cryptococcus neoformans var. neoformans (serotype A) in the southern Japanese prefecture of ...
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INVITRO ANTIMICROBIAL EFFECTS OF GOMPHOCARPUS PURPURASCENS A. RICH AGAINST STANDARD AND CLINICALLY ISOLATED MICROORGANISMS
... The expanding bacterial resistances to antibiotics have become a growing concern worldwide. Gomphocarpus purpurascens is one of the indigenous traditional medicinal plants in Ethiopia. The objective of this study was to ...
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MYCOLOGICAL STUDY ON TRICHOPHYTON INTERDIGITALE ISOLATED FROM CLINICALLY DIAGNOSED CASES OF DERMATOPHYTE INFECTION
... were isolated in ...commonest isolated dermatophytes in which ...interdigitale isolated from cases of tinea unguium (4), tinea pedis (3), and each one with tinea corporis, tinea barbae, tinea ...
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