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Clopidogrel resistance

Clopidogrel Resistance in Neurovascular Stenting: Correlations between Light Transmission Aggregometry, VerifyNow, and the Multiplate

Clopidogrel Resistance in Neurovascular Stenting: Correlations between Light Transmission Aggregometry, VerifyNow, and the Multiplate

... of clopidogrel even 5 days before ...of clopidogrel-resis- tant patients in comparison with that found in cardiology ...of clopidogrel resistance varied from 16% up to 39% in the ...

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Prevalence of clOpidogrel ‘resIstaNce’ in a selected population of patients undergoing elective percutaneous coronary intervention at a tertiary cardiovascular centre in Trinidad: the POINT pilot study

Prevalence of clOpidogrel ‘resIstaNce’ in a selected population of patients undergoing elective percutaneous coronary intervention at a tertiary cardiovascular centre in Trinidad: the POINT pilot study

... was to provide preliminary, exploratory observations of clopidogrelresistance’ in Trinidad which would serve to generate hypotheses for future studies. The sample size was calculated based on speculative ...

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Thromboembolic Complications in Patients with Clopidogrel Resistance after Coil Embolization for Unruptured Intracranial Aneurysms

Thromboembolic Complications in Patients with Clopidogrel Resistance after Coil Embolization for Unruptured Intracranial Aneurysms

... and clopidogrel resistance presented with unruptured left posterior communicating artery aneurysm and endovascular treatment with stent-assisted coil embolization was ...

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Clopidogrel Resistance Is Associated with Thromboembolic Complications in Patients Undergoing Neurovascular Stenting

Clopidogrel Resistance Is Associated with Thromboembolic Complications in Patients Undergoing Neurovascular Stenting

... There are several limitations to this study. As with any retro- spective study, there are potential confounding effects and bias. Practitioners were not blinded, and all complications of the procedures were documented by ...

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Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism

Simultaneous Two-Vessel Subacute Stent Thrombosis Caused by Clopidogrel Resistance from CYP2C19 Polymorphism

... cited. Clopidogrel resistance from CYP2C19 polymorphism has been associated with stent thrombosis in patients undergoing percutaneous coronary intervention with drug-eluting ...as clopidogrel ...

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Multiple Recurrent Stent Thrombosis in a Patient with Coexisting Clopidogrel Resistance and Increased Anticardiolipin Antibodies: A Case Report

Multiple Recurrent Stent Thrombosis in a Patient with Coexisting Clopidogrel Resistance and Increased Anticardiolipin Antibodies: A Case Report

... of clopidogrel resistance and APS despite increasing awareness of resistance to clopidogrel ...and resistance to ...heparin, clopidogrel, and aspirin has been ...and ...

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Clopidogrel resistance "Live" – the risk of stent thrombosis should be evaluated before procedures

Clopidogrel resistance "Live" – the risk of stent thrombosis should be evaluated before procedures

... Every year, millions of people undergo percutaneous coronary intervention (PCI) with intracoronary stent implantation. A patient from the PRAGUE-8 trial (Optimal pre-PCI clopidogrel loading: 600 mg before every ...

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Prevalence and Risk Factors for Aspirin and Clopidogrel Resistance in Cerebrovascular Stenting

Prevalence and Risk Factors for Aspirin and Clopidogrel Resistance in Cerebrovascular Stenting

... Using a point-of-care platelet function test in patients under- going cerebrovascular stent placement is feasible and may be a valuable tool in the prevention of stent-related complications. Given the potential ...

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A Randomized Study Assessing the Effects of Pretreatment with Cilostazol on Periprocedural Myonecrosis after Percutaneous Coronary Intervention

A Randomized Study Assessing the Effects of Pretreatment with Cilostazol on Periprocedural Myonecrosis after Percutaneous Coronary Intervention

... or clopidogrel resistance and myo- ...between clopidogrel resistance and the incidence of periprocedural myonecrosis, despite the lower rate of clopidogrel resistance by ...

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Genetic Polymorphisms of ABCB1 Gene in Patients Having Resistance to Clopidogrel

Genetic Polymorphisms of ABCB1 Gene in Patients Having Resistance to Clopidogrel

... with clopidogrel re- ...given clopidogrel as a part of ..., clopidogrel resistance if PAI > ...for clopidogrel resistance and also it did not influence adverse cardiovascular ...

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Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance - The BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy

Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance - The BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy

... to clopidogrel, the data on the clinical impact of ASA low response in patients treated with dual anti- platelet medication are limited as most studies focus pri- marily on identifying and treating ...

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Platelet Function Testing in Patients Undergoing Neurovascular Procedures: Caught between a Rock and a Hard Place

Platelet Function Testing in Patients Undergoing Neurovascular Procedures: Caught between a Rock and a Hard Place

... that clopidogrel hyper-responsiveness was associated with hemorrhage and, on the other hand, that clopidogrel resistance was associated with thromboembolism—seems like compelling evidence in favor of ...

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Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention

Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention

... and clopidogrel or omeprazole and clopidogrel on the inhibition assay, but platelet residual units and percentage inhibition showed statistically significant improvement after stopping lansoprazole in ...

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Costs and outcomes associated with clopidogrel discontinuation in Medicare beneficiaries with acute coronary syndrome in the coverage gap

Costs and outcomes associated with clopidogrel discontinuation in Medicare beneficiaries with acute coronary syndrome in the coverage gap

... The adverse clinical consequences of stopping or reducing adherence with essential evidenced-based medications can be both severe and costly. Our data add to the literature show- ing that Medicare beneficiaries who face ...

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Comparison of prasugrel and clopidogrel reloading on high platelet reactivity in clopidogrel loaded patients undergoing percutaneous coronary intervention (PRAISE HPR): a study protocol for a prospective randomized controlled clinical trial

Comparison of prasugrel and clopidogrel reloading on high platelet reactivity in clopidogrel loaded patients undergoing percutaneous coronary intervention (PRAISE HPR): a study protocol for a prospective randomized controlled clinical trial

... Regarding the issue of loading and maintenance doses, previous reports have revealed that patients of East Asian ethnicity exhibit on average 30% higher levels of active metabolite compared to Caucasians, with the ...

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Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke

Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke

... showed that aspirin plus dipyridamole led to more major and intracranial bleedings than clopidogrel monotherapy. 12 Re- cent trials have investigated the benefit of a short course of aspirin plus ...

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Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

... plus clopidogrel on platelet activity have aroused people’s ...of clopidogrel in patients undergoing coronary stent placement taking statins ...and Clopidogrel High DOse in stable pa- tients with ...

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Advances in antiplatelet technologies to improve cardiovascular disease morbidity and mortality: a review of ticagrelor

Advances in antiplatelet technologies to improve cardiovascular disease morbidity and mortality: a review of ticagrelor

... The newest P2Y 12 receptor inhibitor ticagrelor has the enhanced ability to reduce mortality, prevent major adverse cardiac outcomes with a low risk of major bleeding compared to clopidogrel. However, the benefits ...

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Comparative fasting bioavailability of two clopidogrel formulations in healthy Mediterranean volunteers: an in vitro–in vivo correlation

Comparative fasting bioavailability of two clopidogrel formulations in healthy Mediterranean volunteers: an in vitro–in vivo correlation

... 2.67, 3.00, 3.50, 4.00, 5.00, 6.00, 8.00, 10.00, 12.00, 16.00, 24.00, 36.00, and 48.00 hours respectively, postdose during each study period. Samples were immediately collected into sodium-heparinized tubes and ...

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GC/MS, FTIR and NMR Studies for the Identification and Characterization of Clopidogrel Bisulfate Degradation Products

GC/MS, FTIR and NMR Studies for the Identification and Characterization of Clopidogrel Bisulfate Degradation Products

... of Clopidogrel Bisulfate under hydrolytic and oxidative stress conditions according to the International Conference on Harmonization (ICH) guideline Q1A (R2) was ...words: Clopidogrel degradation products, ...

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