Clostridioides difficile infection
Efficacy of prolonged tapered and pulsed vancomycin regimen on recurrent Clostridioides difficile infection in the Japanese setting: a case control study
... of Clostridioides difficile infection patient characteristics in the treatment success and failure groups after the vancomycin tapered and pulsed-dose ...
6
Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection
... Clostridioides difficile infection is an important hospital acquired infection [1] with 440 cases reported for the last quarter of 2017 in Ireland ...C. difficile is a Gram-positive ...
15
Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in bile acid farnesoid X receptor fibroblast growth factor pathway
... recurrent Clostridioides difficile infection (rCDI) remain poorly defined, with restored gut microbiota-bile acid interactions representing one possible ...
28
Comparative efficacy of treatments for Clostridioides difficile infection: a systematic review and network meta-analysis
... for Clostridioides difficile infection ...„Clostridium difficile“ and „Meta - analysis“ as well as key words „CDI“, „CDAD“ and „systematic review“, „meta analysis“ (All fields), restricting ...
85
Assessing the social cost and benefits of a national requirement establishing antibiotic stewardship programs to prevent Clostridioides difficile infection in US hospitals
... As policy actions to combat HAIs and antibiotic drug resistance increase, economic evaluations of how to effi- ciently achieve national goals are needed to help inform policy decisions. However, conducting economic ...
17
Burden of Clostridium (Clostridioides) difficile Infection among Patients in Western Asia: A Systematic Review and Meta-Analysis
... Clostridium difficile is the most common cause of hospital-acquired diarrhea affecting particularly hospitalized patients globally ...C. difficile infection (CDI) is challenging and demand new ...
11
Initial therapy affects duration of diarrhoea in critically ill patients with Clostridioides difficile infection (CDI)
... C. difficile testing was requested in 2209 samples from ...C. difficile PCR/ C. difficile culture was ...C. difficile -GDH and toxin A/B) since some had been tested multiple ...
8
Integrated Meta-omics Reveals a Fungus-Associated Bacteriome and Distinct Functional Pathways in Clostridioides difficile Infection
... in Clostridioides difficile infection (CDI) evaluating the role of fungi in CDI or identifying community functions that contribute to the development of this ...
16
Risk factors for Clostridioides difficile infection and colonization among patients admitted to an intensive care unit in Shanghai, China
... ICU patients suffered from CDI, which was significantly higher than the 0.9% of patients on general wards [27]. In our study, we found that the prevalence of CDI was 4.12%, and much higher than that in most studies re- ...
9
Clinical Application and Potential of Fecal Microbiota Transplantation
... Fecal microbiota transplantation (FMT) is a well-established treatment for recurrent Clostridioides difficile infection. FMT has become a more readily available and useful new treatment option as a ...
20
Transmission and clearance of potential procarcinogenic bacteria during fecal microbiota transplantation for recurrent Clostridioides difficile
... The striking difference in the rates of F. nucleatum positivity by qPCR in the parental donors (7 of 7) versus the commercial stool bank donors (0 of 4) was unexpected. F. nucleatum is a common oral pathogen and is ...
13
<p>Interprofessional Antimicrobial Stewardship Influencing <em>Clostridioides difficile</em> Infection: An 8-Year Study Using Antimicrobial Use Density</p>
... for infection control, García-Lecona et al reported that CDI patients in a common isolation unit showed a decreased mortality rate but an increased rate of recurrence than those managed ...
6
Analysis of proteomes released from in vitro cultured eight Clostridium difficile PCR ribotypes revealed specific expression in PCR ribotypes 027 and 176 confirming their genetic relatedness and clinical importance at the proteomic level
... The proteins involved in the assembly of C. difficile fla- gellum and Pro–Pro endopeptidase were present among other proteins revealing higher expression. The quantifi- cation of the proteins involved in the ...
11
Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan
... Clostridioides difficile strain B18-123 was obtained from a stool sample of a 81-year-old elderly male patient who underwent chemotherapy for hepatocellular carcinoma at Medical Hospital of Tokyo Medical ...
7
Ultrasensitive Detection of Clostridioides difficile Toxins A and B by Use of Automated Single Molecule Counting Technology
... of Clostridioides (formerly Clostridium) dif- ficile free toxins in feces lack sensitivity, while nucleic acid amplification tests lack clinical ...difficile infection were tested with the Clarity ...
9
Diversity of Clostridium difficile PCR ribotypes in Europe: results from the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID), 2012 and 2013
... C. difficile ribotypes were found in many countries across Europe and the geo- graphical distribution of some ribotypes suggested regional spread ...C. difficile across ...
11
Correlation between restriction endonuclease analysis and PCR ribotyping for the identification of Clostridioides (Clostridium) difficile clinical strains
... However, molecular epidemiologic investigation of CDI has presented several challenges, in particular the lack of a single portable typing system that is shared amongst the public health and academic communities. Several ...
8
Quantification of Clostridioides (Clostridium) difficile in feces of calves of different age and determination of predominant Clostridioides difficile ribotype 033 relatedness and transmission between family dairy farms using multilocus variable-number tandem-repeat analysis
... acquired Clostridioides (Clostridium) difficile infection (CA-CDI) is a significant health problem in human and veterinary ...C. difficile on such prominent European farming ...interval. ...
10
Evaluation of the Liat Cdiff Assay for Direct Detection of Clostridioides difficile Toxin Genes within 20 Minutes
... ABSTRACT Clostridioides difficile is the main causative agent of antibiotic-associated ...timely infection control mea- sures and appropriate adjustment of antibiotic ...adequate infection con- trol ...
6
Molecular and Susceptibility Analysis of Toxigenic Clostridium difficile Obtained from Adult Patients Suspected of CDI in Trinidad
... C. difficile housekeep- ing gene (see Figure ...C. difficile control ...C. difficile strains. The variability in the C. difficile DNA fragments amplified and sequenced, may have occurred due ...
15