Clostridium botulinum type C
Vaccination with Recombinant Whole Heavy Chain Fragments of Clostridium botulinum Type C and D Neurotoxins
... ELISA. Flat-bottom 96-well plates were coated with 100 l/well of 50-g/ml (for duck serum test) or 10-g/ml (for mice serum test) concentrations of 16 S toxin, followed by incubation overnight at 4°C. After the ...
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Clostridium botulinum Group I Strain Genotyping by 15 Locus Multilocus Variable Number Tandem Repeat Analysis
... Clostridium botulinum is a taxonomic designation that encompasses a broad variety of spore-forming, Gram-positive bacteria producing the botulinum neurotoxin ...(BoNT). C. botulinum is ...
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Genetic Characterization of Clostridium botulinum Associated with Type B Infant Botulism in Japan
... of type B C. botulinum isolates by our BoNT/B subtyping methods will contribute to under- standing of the epidemiology of ...C. botulinum and the infec- tious diseases that it ...
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Application of Clostridium Botulinum Toxin Type D to Control Plateau Zokors in Qinghai–Tibet Plateau Pastoral Areas
... of C. botulinum in 1897, seven types of ...C. botulinum (i.e., A, B, C, D, E, F, and G) have been discovered ...botulism; type C causes botulism in cattle, sheep, mink, ...
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Type E Botulinum Neurotoxin-Producing Clostridium butyricum Strains Are Aerotolerant during Vegetative Growth
... against Clostridium proteins (C. butyricum type E strain BL5262 taxonomy identity 632245) from the NCBI database using Proteome Discoverer version ...
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First Case of Type E Wound Botulism Diagnosed Using Real Time PCR
... ing Clostridium botulinum spores. The spores germinate and botulinum neurotoxin is produced in ...by C. botulinum types A and B ...
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Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified Clostridium botulinum Strain
... of type B in the crude culture, which can complicate the efficacy and interpretation of ...in C. botulinum likely do not occur by the same mechanism in heterologous ...atoxic C. ...
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Recombination and insertion events involving the botulinum neurotoxin complex genes in Clostridium botulinum types A, B, E and F and Clostridium butyricumtype E strains
... both C. botulinum and C. butyricum type E strains; (6) plasmid analyses which show that the bonts within the Bf strain and npBoNT/B strain are located within a plasmid; and (7) the ...
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Infant Botulism Effect of Clostridium and the Involvement of Sudden Infant Death Syndrome (SIDS): Review
... perfringens. C. tetani and C. botulinum produce the most potent biological toxins known to affect ...One type of those toxins product involves a neuro-paralytic disease in human and ...by ...
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Genomic Epidemiology of Clostridium botulinum Isolates from Temporally Related Cases of Infant Botulism in New South Wales, Australia
... of C. botulinum type A ...of C. botulinum type A ...from C. botulinum B ...from C. botulinum B ...
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Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells
... Differentiation of SiMa neuroblastoma cells has been shown to greatly enhance their sensitivity to BoNT type A paving the way for a subnanomolar sensitive assay for potency of relevant therapeutic products [18]. ...
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Diagnosis of Clostridium Sporogenes (Uncle Fester Reference) pdf
... THE EGG YOLK PLATE REACTION FOR THE PRESUMPTIVE DIAGNOSIS OF CLOSTRIDIUM SPOROGENES AND CERTAIN SPECIES OF THE GANGRENE AND BOTULINUM GROUPS L.. McCLUNG AND RUTH TOABE Bacteriological La[r] ...
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Protein Biotoxins of Military Significance
... pathogen Clostridium perfringens is a major cause of human and veterinary enteric disease largely because this bacterium can produce several toxins when present inside the gastrointestinal ...
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An Ultrasensitive Gold Nanoparticle based Lateral Flow Test for the Detection of Active Botulinum Neurotoxin Type A
... timely botulinum antitoxin ...human-derived botulinum antitoxin has been recommended to administer as early as possible by some experts ...in Clostridium botulinum lysis and subsequent BoNTs ...
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Toxins as biological weapons for terror—characteristics, challenges and medical countermeasures: a mini-review
... Toxins cannot be grown in culture or identified by sim- ple genetic sequencing of amino acids, making detection and treatment a more complex challenge. Furthermore, poisoning often presents with nonspecific clinical ...
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IN SILICO ANALYSIS AND HOMOLOGY MODELING OF TARGET PROTEINS FOR CLOSTRIDIUM BOTULINUM
... The completion of genome sequences of pathogenic bacteria and the completion of human genome project has provided lot amount of data that can be utilized to design vaccines and drug targets. Recently adopting strategies ...
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Selective medium for isolation of Clostridium botulinum from human feces
... This assumption is based on the facts that: i the fecal bacterial flora of the human infant is less complex than that of the adult; ii only types A, B, and F all proteolytic have been as[r] ...
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Patient considerations in the treatment of cervical dystonia: focus on botulinum toxin type A
... BoNT type A and B for the treatment of CD in ...The type A formula- tions include: onabotulinumtoxinA (Botox; Allergan, ...BoNT type B is rimabotulinumtoxinB (Myobloc; Solstice Neurosciences, LLC, a ...
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Comparison of DNA Fingerprinting Methods for Use in Investigation of Type E Botulism Outbreaks in the Canadian Arctic
... of C. botulinum type E has been traditionally performed by visual examination, presumably because of the presence of a large number of low-molecular-weight fragments and the frequent occurrence of ...
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Botulinum toxin type A in the treatment of patients with cervical dystonia
... musculature. Botulinum toxin type A is a safe and effective treatment of this disabling and often painful ...of botulinum toxin type A are available worldwide to treat patients with cervical ...
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