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Clostridium difficile infection (CDI)

Efficacy of vancomycin extended dosing regimens for treatment of simulated Clostridium difficile infection (CDI) within an in vitro human gut model

Efficacy of vancomycin extended dosing regimens for treatment of simulated Clostridium difficile infection (CDI) within an in vitro human gut model

... Crowther, GS, Chilton, CH, Longshaw, C et al. (5 more authors) (2016) Efficacy of vancomycin extended dosing regimens for treatment of simulated Clostridium difficile infection (CDI) within an ...

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Mortality and Clostridium difficile infection: a review

Mortality and Clostridium difficile infection: a review

... by Clostridium difficile ranges from uncomplicated diarrhoea to pseudomem- branous colitis and toxic megacolon, and is often termed ‘Clostridium difficile -associated diarrhoea ’ or ...

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Impact of Clostridium difficile infection among pneumonia and urinary tract infection hospitalizations: an analysis of the Nationwide Inpatient Sample

Impact of Clostridium difficile infection among pneumonia and urinary tract infection hospitalizations: an analysis of the Nationwide Inpatient Sample

... *Bonferroni adjusted P < 0.0017 CDI = Clostridium difficile infection, UTI = Urinary tract infection, OR = odds ratio, CI = confidence interval, IRR = incidence rate ratio a Binary logis[r] ...

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Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of Clostridium difficile infection (CDI)?

Is there a relationship between the presence of the binary toxin genes in Clostridium difficile strains and the severity of Clostridium difficile infection (CDI)?

... in Clostridium difficile strains and the severity of Clostridium difficile infection (CDI)? European Journal of Clinical Microbiology and Infectious Diseases, 36 ...

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Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C  difficile PCR ribotype 027 in central China

Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C difficile PCR ribotype 027 in central China

... Clostridium difficile infection (CDI), which is caused by toxigenic ...C. difficile (TCD), has been linked to health- care facility-associated (HCFA) diarrhea since 1977 ...of ...

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Clostridium difficile infection in Italian urban hospitals: data from 2006 through 2011

Clostridium difficile infection in Italian urban hospitals: data from 2006 through 2011

... Clostridium difficile infection (CDI) is the most frequent cause of health care-associated infectious diarrhea in industrialized ...of CDI has been low, with death as a direct or ...

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Point Counterpoint: What Is the Current Role of Algorithmic Approaches for Diagnosis of
            Clostridium difficile Infection?

Point Counterpoint: What Is the Current Role of Algorithmic Approaches for Diagnosis of Clostridium difficile Infection?

... of Clostridium difficile infection in the industrialized world coupled with the development of new testing technologies for detection of this organism, there has been renewed interest in the ...

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Evaluating risk factors for Clostridium
                     difficile infection in adult and pediatric hematopoietic cell transplant recipients

Evaluating risk factors for Clostridium difficile infection in adult and pediatric hematopoietic cell transplant recipients

... C. difficile within pediatric facilities, particu- larly since asymptomatic colonized children may act as ...C. difficile reservoirs [22–25] and have previously been linked to transmission [36, ...gesting ...

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Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study

Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study

... that CDI is likely to recur in approximately 25% of the patients treated for iCDI with vancomycin ...of CDI were identified. Most stools submitted for C. difficile testing at the BJH microbiology ...

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National age group trends in Clostridium difficile infection incidence and health outcomes in United States Community Hospitals

National age group trends in Clostridium difficile infection incidence and health outcomes in United States Community Hospitals

... Several factors could contribute to the disparate CDI incidence increase and health outcomes among the elderly compared to other age groups. Advanced pa- tient age has been previously linked to an increase risk ...

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Proton pump inhibitors increase the risk for hospital acquired Clostridium difficile infection in critically ill patients

Proton pump inhibitors increase the risk for hospital acquired Clostridium difficile infection in critically ill patients

... The short duration of PPI exposure that is associated with CDI stimulates controversy regarding the true path- ophysiologic mechanism of this relationship. One hypo- thesis is that increased gastric pH levels ...

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Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non C  difficile Associated Diarrhea from Healthy Controls

Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non C difficile Associated Diarrhea from Healthy Controls

... of CDI (not recurrent CDI), and their stool sample was ...C. difficile using the ...C. difficile antigen glutamate dehydrogenase (GDH) and the C. difficile toxin proteins A and ...C. ...

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Cost of hospital management of Clostridium difficile infection in United States—a meta analysis and modelling study

Cost of hospital management of Clostridium difficile infection in United States—a meta analysis and modelling study

... of CDI in long-term care facilities, where about 9 % of CDI patients were discharged to for an average of 24 days of ...mary CDI from recurrent CDI cost in our review because only two studies ...

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Risk factors for Clostridium difficile infection in surgical patients hospitalized in a tertiary hospital in Belgrade, Serbia: a case–control study

Risk factors for Clostridium difficile infection in surgical patients hospitalized in a tertiary hospital in Belgrade, Serbia: a case–control study

... medicine. CDI results in a wide spectrum of clinical con- ditions, including an asymptomatic carrier state; mild, self-limited diarrhea; pseudomembranous colitis; and fulminant ...for CDI in- clude the ...

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Clostridium difficile infection health disparities by race among hospitalized adults in the United States, 2001 to 2010

Clostridium difficile infection health disparities by race among hospitalized adults in the United States, 2001 to 2010

... of CDI where race was assessed as an inde- pendent risk factor [13, 27, ...recurrent CDI in black patients in a study designed to assess the risk of CDI recurrence associated with proton pump ...

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A systematic review for pursuing the presence of antibiotic associated enterocolitis caused by methicillin resistant Staphylococcus aureus

A systematic review for pursuing the presence of antibiotic associated enterocolitis caused by methicillin resistant Staphylococcus aureus

... Abbreviations: MRSA methicillin-resistant Staphylococcus aureus, c/w consistent with, AAE antibiotic associated enterocolitis, CDI Clostridium difficile infection, TSS toxic shock syndro[r] ...

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Prediction of microbe–disease association from the integration of neighbor and graph with collaborative recommendation model

Prediction of microbe–disease association from the integration of neighbor and graph with collaborative recommendation model

... Abbreviations COPD: chronic obstructive pulmonary disease; MS: mass spectrometry; CDI: clostridium difficile infection; NGRHMDA: neighbor- and graph-based combined recommendation model f[r] ...

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Clinical Application and Potential of Fecal Microbiota Transplantation

Clinical Application and Potential of Fecal Microbiota Transplantation

... recurrent Clostridium difficile infection (reclassified as Clostridioides difficile) (rCDI) (1, 2), with cure rates of 80–90% ...for CDI pathogenesis) seems to underlie the observed ...

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Fecal microbiota transplantation against intestinal colonization by extended spectrum beta lactamase producing Enterobacteriaceae: a proof of principle study

Fecal microbiota transplantation against intestinal colonization by extended spectrum beta lactamase producing Enterobacteriaceae: a proof of principle study

... have previously shown that FMT can successfully treat recurrent Clostridium difficile infection (CDI), with an overall cure rate of more than 90% [6, 7]. To date, over eight case reports and ...

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Patient Risk Stratification with Time-Varying Parameters: A Multitask Learning Approach

Patient Risk Stratification with Time-Varying Parameters: A Multitask Learning Approach

... The proliferation of electronic health records (EHRs) frames opportunities for using ma- chine learning to build models that help healthcare providers improve patient outcomes. However, building useful risk ...

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