collective cell migration
The Maf factor Traffic jam both enables and inhibits collective cell migration in Drosophila oogenesis
... Border cell cluster (BCC) migration in the Drosophila ovary is an excellent system to study the gene regulatory network that enables collective cell ...BCC migration coincides with a ...
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Convergent extension: using collective cell migration and cell intercalation to shape embryos
... of collective migration (reviewed by Friedl and Gilmour, ...oval-shaped cell sheet in a straight path away from the germ ring margin towards the animal pole of the ...of cell protrusions ...
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Collective cell migration: Implications for wound healing and cancer invasion
... tight cell-cell junctions, a process named collective ...such migration, cells move as coherent groups, large cell sheets, strands or tubes rather than ...regarding collective ...
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The secreted AdamTS A metalloprotease is required for collective cell migration
... in collective cell migration, we turned to the embryonic SGs, which express AdamTS-A prior to and during posterior ...coordinated cell shape changes, cell rearrangement, growth and ...
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Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors.
... and collective cell migration, it is possible that cells that have undergone a complete EMT and individual cell migration may also contribute to ...
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Jamming state transition and collective cell migration
... by collective cell migration is discussed on a model system such as cell aggregate rounding after uni-axial compression between parallel plates based on the data from the ...literature. ...
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Guidance receptor promotes the asymmetric distribution of exocyst and recycling endosome during collective cell migration
... The next question is how the polarized distribution of recycling and tethering activity is initiated in border cells. We demonstrated that this was likely to be induced by the guidance receptors in response to the ...
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Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis
... of migration, and Rac is the major signaling pathway responsible for the ...phosphorylation, migration and protrusion defects of RacN17 by S3E, Pak or LIMK further indicates that Rac partly promotes BC ...
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Collective cell migration in morphogenesis and cancer
... single cell migration, the forces that drive cell movement reside in cytoskeletal dynamics that are transferred to the extra- cellular scaffold via adhesion ...Initial cell polarization is ...
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Inhibition of Rho-associated kinases disturbs the collective cell migration of stratified TE-10 cells
... between cell numbers and the velocity of the wounded edge. The volume of the cell suspension plated into the hole in the center of each PDMS stencil was increased in 50-µL increments from 100 to 200 ...the ...
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Collective cell migration of smooth muscle and endothelial cells: impact of injury versus non-injury stimuli
... a migration of both endothelial and smooth muscle cells. Migration methods that are able to tease out involved factors are useful for in vitro mechanistic ...on cell migration, i.e. injury and ...
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A common framework for EMT and collective cell migration
... of collective epithelial cell migration, this continuous modulation of E-cadherin and other junctional components, such as catenins, is key to maintaining tissue integrity throughout cell ...
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PDGF A suppresses contact inhibition during directional collective cell migration
... underlapped cell body to stabilize ...a cell body, they collapsed after initial spreading, as in control cells: filiform protrusions extended, whereas the lamellipodium ...
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Hypoxia, partial EMT and collective migration: emerging culprits in metastasis
... epithelial cell cluster has been shown to cause distant polyclonal metastases in mouse model of breast cancer ...Therefore, collective invasion and metastasis can be fuelled by at least a partial retention ...
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The devil is in the mesoscale: mechanical and behavioural heterogeneity in collective cell movement
... Keywords Heterogeneity, mesoscale, tissue mechanics, collective cell migration, convergence and extension Highlights ¥ Tissue morphogenesis requires tightly coordinated behaviours such a[r] ...
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Surrounding tissues canalize motile cardiopharyngeal progenitors towards collective polarity and directed migration
... study collective cell migration (Beh et ...cadherin-based cell-cell adhesion throughout migration (Norton et ...and collective behavior via tissue-specific inhibition of ...
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Collective cancer cell invasion induced by coordinated contractile stresses
... in cell elongation and polarization ...amoeboid migration [18] because the leading or elongated cells presumably degrade the collagen creating tracks for other cells to follow with less resistance; ...
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What mechanisms drive cell migration and cell interactions in Pleurodeles?
... Int I Dev Bioi 40 675 683 (1996) 675 What mechanisms drive cell migration and cell interactions in Pleurodeles? JEAN CLAUDE BOUCAUT*, LEA CLAVILlER, THIERRY DARRIBERE, MICHEL DELARUE, JEAN FRANt; OIS[.] ...
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The Role of the Exocyst in Exocytosis and Cell Migration
... The exocyst, an evolutionarily conserved octameric protein complex, plays a crucial role in the tethering of post-Golgi secretory vesicles to the plasma membrane for exocytosis and cell migration. How the ...
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Paxillin: a crossroad in pathological cell migration
... A main characteristic of transformed epithelial cancer cells is the ability to survive and proliferate in the absence of contact with immobilized ECM [105]. Paxillin is known to acquire gain of function mutations that ...
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