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Colon Cancer

Use of capecitabine in management of early colon cancer

Use of capecitabine in management of early colon cancer

... The next challenge was to establish the role of capecitabine in adjuvant settings in colon cancer. The Xeloda in Adjuvant Chemotherapy Trial (X-ACT) investigated the efficacy and safety of capecitabine ...

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Can licorice lick colon cancer?

Can licorice lick colon cancer?

... COX-2 promotes colon cancer. While both nonselective NSAIDs and selec- tive COX-2 inhibitors reduce disease burden, their adverse gastrointestinal and cardiovascular side effects limit their therapeutic ...

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Vasohibin-1 suppresses colon cancer

Vasohibin-1 suppresses colon cancer

... with immunohistochemical staining analyses further confirmed that VASH1 and CD34 molecules were co- expressed in blood endothelial cells in colon cancer tissues (Supplemental Figure 1A). We then ...

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Exercise as a prescription therapy for breast and colon cancer survivors

Exercise as a prescription therapy for breast and colon cancer survivors

... of cancer survivors, ie, those with breast or colon cancer without metastasis, will be considered for the “exercise prescription” program at our sports medicine unit, and will be enrolled after ...

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Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis

Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis

... in colon CSCs with RSV-GSE ...in colon CSCs with shRNA attenuated ...of colon cancer cases, and marks transition to metastasis [17, ...in colon CSCs independent of their p53 status ...

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Immunohistochemical Study of OTUB1 Expression in Colon Cancer

Immunohistochemical Study of OTUB1 Expression in Colon Cancer

... Sun et al. found that OTUB1 could induce the p53- dependent cellular apoptosis and inhibit proliferation by regulating the ubiquitination of p53[10]. Herhaus et al. found that Otub1 enhanced TGF-mediated gene ...

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Deep learning with sampling in colon cancer histology

Deep learning with sampling in colon cancer histology

... This study applied a deep-learning cell identification algorithm to diagnostic images from the colon cancer repository at The Cancer Genome Atlas (TCGA). Within-image sampling improved performance ...

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ACLY facilitates colon cancer cell metastasis by CTNNB1

ACLY facilitates colon cancer cell metastasis by CTNNB1

... Previously, researchers mainly focus on glucose and glutamine metabolism in the field of tumor metabolism and metastasis. There are few studies on lipid metabol- ism in tumor metastasis. Altered lipid metabolism in ...

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Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer

Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer

... Comprehensive Cancer Network (NCCN) guidelines, all patients diag- nosed with colorectal cancer under the age of 70, or over the age of 70 and who also meet the Bethesda Guidelines, should undergo tumor ...

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Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy

Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy

... promote colon cancer has been identified ...promoting colon cancer through exclusive utilization of GP130 homodimers when bound to its receptor, IL-11R ...mediated cancer develop- ment ...

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Epithelial stromal interactions in colon cancer

Epithelial stromal interactions in colon cancer

... Int J De\ BioI 37 203 211 (1993) 203 Epithelial stromal interactions in colon cancer FRED T BOSMAN", ADRIAAN DE BRU'INE', CLAUDIE FLOHIL', ANNEKE VAN DER WURFF', JOOP TEN KATE' and WINAND W M DINJENS'[.] ...

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Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts

Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts

... Figure 7 Cathelicidin-mediated inhibition of EMT and fibroblast-supported colon cancer cell proliferation may be cytoskeleton-mediated. (A) Tubulin tracker staining with nuclear staining in human ...

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The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer

The expression and significance of Gal-3 and MUC1 in colorectal cancer and colon cancer

... colorectal cancer tissues and the tis- sues adjacent to carcinoma from 45 cases from the Colorectal Cancer Surgery Department of Zhengzhou People’s Hospital from December of 2009 to June of ...colorectal ...

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Heterogeneity of colon cancer: from bench to bedside

Heterogeneity of colon cancer: from bench to bedside

... of colon cancers arising from the diverse sides of the colon–rectum as well as for the sensitivity to the therapy, including ...right colon cancer and the left colorectal ...colorectal ...

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4112 killed colon cancer cells at IC

4112 killed colon cancer cells at IC

... inhibit cancer stem cell proliferation using a primary (1°) colonosphere formation ...HT-29 colon cancer cells were grown in low adhesion plates to form spheres as previously ...of colon ...

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EMT is the dominant program in human colon cancer

EMT is the dominant program in human colon cancer

... prognosis colon tumors, suggesting proliferation may not play a critical role in colon cancer progression, yet we know it is important for colon epithelial biology in crypt ...that ...

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PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells

... the current study suggest that expression of PUMA can be a useful indicator for predicting response of colon cancer cells to osimertinib. In addition to PUMA induction, other Bcl-2 family members are also ...

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Cytotoxic assays for Lung and Colon cancer

Cytotoxic assays for Lung and Colon cancer

... worldwide. Colon cancer and lung cancer are the most frequently diagnosed malignancies in the ...of colon cancer is estimated to be ...of colon cancer worldwide.The ...

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Proteomics analysis of colon cancer progression

Proteomics analysis of colon cancer progression

... colorectal cancer though frequently using in vitro cell line models ...only colon tissues from exactly same stage (for non-metastatic colon cancer (CC ...in colon and were node-negative ...

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Mutational signatures in colon cancer

Mutational signatures in colon cancer

... in colon cancer, and the burdens of the new signatures in MSI-H tumors were over-represented in the tumors with high muta- tion ...the cancer, we can roughly infer which tumors they are based on ...

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