Colonic inflammation
Exosomes from mesenchymal stromal cells reduce murine colonic inflammation via a macrophage-dependent mechanism
... improved colonic inflammation, as shown by an increased colon length (Figure ...in colonic myeloperoxidase (MPO) activity, suggesting less neutrophil infiltration (Figure ...
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Inflammasome-independent role of NLRP12 in suppressing colonic inflammation regulated by Blimp-1
... of colonic inflammation, colon length was measured by day 7; the colon length of the DSS group was shorter compared to the control group and the TLR4 deficient group (Figure ...DSS-induced colonic ...
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MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice
... on colonic inflammation has not yet been ...in colonic explants and macrophage cells isolated from ...Winnie colonic explants shows, for the first time, the contribution of inflammatory ...
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The endogenous cannabinoid system protects against colonic inflammation
... or inflammation has been suggested to be related to the initiation of these diseases (2, ...of colonic inflammation and to test anti-inflammatory drugs (4, ...
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<p>Effects of Exposure to Mild Hyperbaric Oxygen on DSS-Induced Colonic Inflammation and Diarrhea in Rats</p>
... the colonic in fl ammation grade between rats with DSS-induced colonic in fl ammation accompanied with or without exposure to ...the colonic mucosa and to improve colonic in fl ...of ...
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Outcomes of inflammatory bowel disease in patients with eosinophil predominant colonic inflammation
... This is a retrospective study and is liable to inherit limita- tions of the retrospective method. The primary outcome (disease flare) was based on chart review diagnosis, the number of disease flares can be ...
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Neurotensin is a proinflammatory neuropeptide in colonic inflammation
... the colonic mucosa in response to toxin A adminis- tration ...rat colonic explants, NT-mediated mucos- al mast cell degranulation is blocked by a specific antag- onist to NK-1 receptor ...
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Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling
... Many studies have suggested that NF-κB signaling is a critical link between inflammation and carcinogenesis. Although the involvement of O-GlcNAcylation in NF-κB signaling has been suggested, the molecular ...
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<p>Colonic inflammation affects myenteric alpha-synuclein in nonhuman primates</p>
... Expression of HLA-DR, a marker of antigen presenting cells, was observed on the surface of cells with circular/ ovoid shape in all animals, as well as on macrophage-like cells (Figure 2A). HLA-DR-ir %AAT quanti fi cation ...
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Alteration of colonic excitatory tachykininergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration
... rat colonic tissues following central dopaminergic ...of colonic inflammation in tissues isolated from 6-OHDA rats, characterized by in- creased levels of MDA, TNF, and IL-1β, thus suggesting the ...
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Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat
... that colonic inflamma- tion indeed induces bladder hyperactivity with minimum change in the morphology of the urinary organ, suggest- ing a neurogenic mechanism in colon-to-bladder cross- ...
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A murine model of ulcerative colitis: induced with sinusitis-derived superantigen and food allergen
... dose-dependent colonic inflammation [13]. SEB can also induce colonic epithelial barrier dysfunction [14] that may promote uptake of exogenous antigens, microbial products and other nox- ious ...
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Original Article PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer
... control (P < 0.001, P = 0.017 and P = 0.003 respectively) and vehicle treated group (P = 0.001, P = 0.006 and P = 0.021 respectively) (Figure 2G). To further prove the influence of PAF signaling on colonic ...
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The use of cannabinoids in colitis: a systematic review and meta analysis
... induced colonic inflammation using surgical arterial ligation or puncture of the colon and 1 induced colitis with interleukin-10 (IL-10) knock-down and DSS (figure ...
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Raman spectroscopy of endoscopic colonic biopsies from patients with ulcerative colitis to identify mucosal inflammation and healing
... Ulcerative colitis (UC) is a chronic inflammatory condition, which is diagnosed in patients worldwide, irrespective of ethnicity and anthropological origin, and is becoming more prevalent with time. Amongst the human ...
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Effect of Concentrated Apple Extract on Experimental Colitis Induced by Acetic Acid
... Reactive oxygen and nitrogen species (ROS/RNS) play a crucial role in inflammatory bowel disease (IBD) exacerbating the chronic inflammatory process. Endogenous and diet antioxidants can neutralize these compounds. The ...
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Case Report Spontaneous expulsion of a giant colonic lipoma: a case report and literature review
... that colonic lipomas have unusual symptoms, they should be taken into consideration for differential diagnosis of tumors of the large ...the colonic lipoma may separate from its root and be expelled from ...
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Extending colonic mucosal microbiome analysis—assessment of colonic lavage as a proxy for endoscopic colonic biopsies
... the colonic mucosa and tends to shift naturally around the bowel with the aid of peristalsis and the constant changes in the movement and posture of the subject ...and colonic lavage samples were collected ...
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Mucus mediated protection against acute colitis in adiponectin deficient mice
... inhibition, we did not see a reciprocal effect in the expression levels of Math1 and Hes1 genes in the present study. These observations may represent a pro- tective adaptation in the gut from DSS insult, where there is ...
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Colonic diverticulosis is not a risk factor for colonic adenoma
... Results: A total of 17,456 subjects were enrolled. The prevalence of colonic diverticulosis and adenoma was 2.4% and 13.2%, respectively. With regard to distribution of diverticula, most (365/424, 86.1%) were ...
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