colony-stimulating activity(ies)
Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony stimulating activity
... megakaryocyte colony forming units (CFU-GEMM) as assayed in methylcellulose ...granulocyte-macrophage colony stimulating activity (GM-CSA) is shown to have both burst promoting activity ...
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Regulation of colony stimulating activity production Interactions of fibroblasts, mononuclear phagocytes, and lactoferrin
... Granulocyte-monocyte colony-stimulating activity (CSA) was measured in supernatants of the fibroblast cultures with normal T lymphocyte-depleted, phagocyte-depleted, low density bone marrow target ...
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Recombinant murine granulocyte macrophage colony stimulating factor has megakaryocyte colony stimulating activity and augments megakaryocyte colony stimulation by interleukin 3
... megakaryocyte colony formation. The dose-response curve for megakaryocyte colony induction with rGM-CSF showed plateau megakaryocyte stimulation at 9 ...megakaryocyte colony induction) was added to ...
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Interleukin 1 stimulates granulocyte macrophage colony stimulating activity release by vascular endothelial cells
... recruiting activity (MRA) a monokine that stimulates endothelial cells to produce granulocyte macrophage-colony-stimulating activity (CSA) by endothelial cells, show that it is a thermolabile ...
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Cyclic hematopoiesis Effects of endotoxin on colony forming cells and colony stimulating activity in grey collie dogs
... serum colony-stimulating activity did not show cyclic variation with the cyclic neutrophil counts in untreated grey collies and was not altered by chronic endotoxin ...
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Interleukin 1 stimulates fibroblasts to produce granulocyte macrophage colony stimulating activity and prostaglandin E2
... Granulocyte-macrophage colony-stimulating activity (GM-CSA) can be produced by a variety of normal cell types including mononuclear phagocytes, activated T lymphocytes, endothelial cells, and ...
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Viral infection of vascular endothelial cells alters production of colony stimulating activity
... stimulating activity (CSA). Endothelial cells are a known source of CSA and may be transiently or persistently infected during a number of viral infections, including infection with herpes simplex virus ...
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The effect of high dose chemotherapy on hemopoietic colony stimulating activity in the plasma of patients with multiple myeloma
... haematological malignancies such as leukaemia in which tumour cells are sufficiently sensitive to radiation and chemotherapy to allow eradication of the malignant cells. Successful ABMT is associated with some rejection ...
330
Release of colony stimulating activity from thymus derived lymphocytes
... Additional evidence that these two antisera have different specificities rests on the following observations: a the two antisera give additive killing of lymphocytes when used together; [r] ...
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A study of molecules involved in the regulation of the growth of haematopoietic cells and heart muscle cells in culture
... Scotland) containing 15% (v/v) foetal calf serum (Flow Laboratories, Irvine, Scotland) L-asparagine and D.E.A.E. - Dextran (Pharmacia, Uppsala, Sweden) were added to each petri dish. The petri dishes were placed in a ...
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A screen for peptide agonists of the G CSF receptor
... Moreover, agonistic peptides have been found for the EPO receptor (EPO-R), functionally very close to the G- CSF receptor (G-CSF-R), both derived from the EPO sequence [24] or fully novel [25,26]. Indeed, one of the ...
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Effects of immunotherapy on mortality in neonates with suspected or proven sepsis: a systematic review and network meta-analysis
... granulocyte-colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF) and human antibodies to endotoxin (antilipo- polysaccharide), have been evaluated for ...
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Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system
... Granulocyte colony-stimulating factor; GM-CSF: Granulocyte macrophage colony- stimulating factor; Ig: Immunoglobulin; INF: Interferon; IL: Interleukin; PDGF: Platelet-derived growth factor; ...
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Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade
... cells with transition of intratumoral macrophages towards an M1-like phenotype, and (5) overcome the fibrotic and immunosuppressive TME of PDAC, while altogether producing enhanced antitumor activity when compared ...
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The effect of myeloid growth factors on phagocyte-endothelium interactions.
... granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) were initially defined ...
226
GM-CSF as a therapeutic target in autoimmune diseases
... Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been known as a hematopoietic growth factor and immune modulator. Recent studies revealed that GM-CSF also had pro-inflammatory functions and ...
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Myeloid-derived suppressor cells in hematological malignancies: friends or foes
... Myeloid-derived suppressor cells (MDSCs) are a newly identified, heterogeneous population of immature mye- loid cells that are characterized by the ability to suppress both innate and adaptive immune responses. The role ...
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The effect of inhibition of leukotriene synthesis on the activity of interleukin-8 and granulocyte-macrophage colony-stimulating factor
... Priming of neutrophil 5-LO activity by IL-8 and GM-CSF: The major metabolites of endogenous arachidonate in neutrophils stimulated with the. Ca 2+[r] ...
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Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis
... Conclusions While this meta-analysis demonstrated that G-CSF or GM-CSF therapy significantly increased the reversal rate from infection, it was not associated with a significant reductio[r] ...
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Cytokines as Adjuvants for the Induction of Anti-Human Immunodeficiency Virus Peptide Immunoglobulin G (IgG) and IgA Antibodies in Serum and Mucosal Secretions after Nasal Immunization
... gen, while IL-12 was not effective when used alone (Fig. 1). Mucosal epithelial cells express receptors for IL-1 and GM- CSF (13, 34), and therefore, IL-1 and GM-CSF are able to bind to their specific receptors on the ...
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