Colony-Stimulating Factor Therapy
Recombinant Human Granulocyte Colony-stimulating Factor Therapy for Sepsis in Infants With Neutropenia
... A randomized, placebo- controlled trial of granulocyte colony-stimulating factor administration to newborn infants with neutropenia and clinical signs of early-onset sepsis.. Lieschke GJ[r] ...
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Granulocyte colony stimulating factor producing rectal cancer
... Case presentation: A 57-year-old man was admitted for the surgical removal of a rectal cancer. Some hepatic tumors in the liver were revealed concurrently, and their appearance suggested multiple liver metastases. Low ...
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Effect of Combination Therapy Using Hypothermia and Granulocyte Colony-Stimulating Factor in a Rat Transient Middle Cerebral Artery Occlusion Model
... granulocyte colony-stimulating factor (G-CSF) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in Wistar ...
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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
... CSF1: Colony-stimulating factor 1; CSF1R: Colony-stimulating factor 1 receptor; CTLA4: Cytotoxic T-lymphocyte- associated protein 4; DC: Dendritic cells; DLT: Dose-limiting ...
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Anti Granulocyte Macrophage Colony Stimulating Factor Autoantibodies Are a Risk Factor for Central Nervous System Infection by Cryptococcus gattii in Otherwise Immunocompetent Patients
... the therapy for both species is the same ...risk factor for ...causative factor (8, 12), leading to diagnostic heterogeneity in the underlying lung ...
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Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade
... CSF1: colony-stimulating factor 1; CSF1R: colony-stimulating factor 1 receptor; CR: complete response; CTLA-4: cytotoxic T-lymphocyte associated protein 4; CTLs: cytotoxic ...
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A screen for peptide agonists of the G CSF receptor
... Granulocyte-colony stimulating factor (G-CSF) is one the most widely employed protein drugs. It is mostly used for counteracting neutropenia in patients receiving chemotherapy [1], but also for stem ...
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Megakaryocyte growth and development factor Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy induced thrombocytopenia
... development factor (r-HuMGDF) behaves both as a megakaryocyte colony stimulating factor and as a differentiation factor in human progenitor cell ...Megakaryocyte colony formation ...
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Effects of immunotherapy on mortality in neonates with suspected or proven sepsis: a systematic review and network meta-analysis
... granulocyte-colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF) and human antibodies to endotoxin (antilipo- polysaccharide), have been ...
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Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis
... GM-CSF therapy versus placebo in sepsis, the first mHLA-DR-guided immunostimulatory treatment, indi- cating that administration of GM-CSF to patients in the immunosuppressive phase of sepsis reversed the charac- ...
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Different effects of granulocyte colony-stimulating factor and erythropoietin on erythropoiesis
... Anemia can develop from loss of RBCs, a reduction in RBC production, increased destruction of RBCs, or a shorter RBC lifespan. The World Health Organization de- fines anemia as a hemoglobin level lower than 12 g/dl in ...
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Granulocyte Colony-Stimulating Factor Serum and Urine Concentrations in Neutropenic Neonates Before and After Intravenous Administration of Recombinant Granulocyte Colony-Stimulating Factor
... If our interpretation is correct, that G-CSF-Rs are either saturated or down-regulated in neutropenic neonates with sepsis and shock, the administration of rG-CSF to these patients probably adds little to their care. ...
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Granulocyte Colony-Stimulating Factor Use in a Large Iranian Hospital: Comparison with American Society of Clinical Oncology (ASCO) Clinical Practice Guideline
... of therapy, major side effects), types of cancer and chemotherapy regimen, laboratory data (including WBC counts with differential counts, hemoglobin, platelet counts and RBC) and outcomes of GCSF treatment ...
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Granulocyte-Colony Stimulating Factor Receptor, Tissue Factor, and VEGF-R Bound VEGF in Human Breast Cancer In Loco
... Introduction of G-CSFs into clinical prac- tice revolutionized oncological therapy and en- abled effective prevention of FN associated with chemo- and radiotherapy [26]. It has been prov- en that G-CSFR is ...
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Leukemoid reaction and autocrine growth of bladder cancer induced by paraneoplastic production of granulocyte colony stimulating factor – a potential neoplastic marker: a case report and review of the literature
... granulocyte colony-stimulating factor level was 10 times the normal ...granulocyte colony-stimulating ...granulocyte colony-stimulating factor/receptor biological ...
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An Update on Pathophysiology and Medical Management of Endometriosis
... growth factor inhibitor ,which have been shown to exert anti-angiogenic effects on endometriotic lesions, ...growth factor, FGFR, fibroblast growth factor receptor; HIF, hypoxia inducible ...
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ROLE OF GRANULOCYTE COLONY STIMULATING FACTOR IN IMPROVING ENDOMETRIAL THICKNESS IN INFERTILITY
... thoughts which define a cut off for the thin endometrium. Some investigators say that pregnancy occurs when endometrium reaches ≥7mm, and others that ≥8 mm or ≥9 mm is required for successful conception. [6] In our study ...
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Induction of junB expression, but not c jun, by granulocyte colony stimulating factor or macrophage colony stimulating factor in the proliferative response of human myeloid leukemia cells
... granulocyte colony-stimulating factor (G-CSF) and macrophage colony-stimulating factor (M-CSF) on human hematopoietic cells have been reported, but the intranuclear mechanism of ...
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Myeloid-derived suppressor cells in hematological malignancies: friends or foes
... Similar to other tumor models, in MM patients, Arg-1, iNOS, ROS, and TNF-α were found to be overexpressed by MDSCs [45, 47]. For example, one recent study re- ported that PMN-MDSCs and their function through in- creased ...
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Recombinant murine granulocyte macrophage colony stimulating factor has megakaryocyte colony stimulating activity and augments megakaryocyte colony stimulation by interleukin 3
... megakaryocyte colony formation. The dose-response curve for megakaryocyte colony induction with rGM-CSF showed plateau megakaryocyte stimulation at 9 ...megakaryocyte colony induction) was added to ...
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