Colony stimulating factors
Clinical implications, safety, efficacy of Recombinant Human Granulocyte Colony-Stimulating Factors and Pegylated Equivalent
... granulocyte-colony stimulating factors (G-CSFs) has changed several therapeutic approaches in oncology and hematology, leading to a safe exploitation of more intensive chemotherapy; especially, among ...
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Colony stimulating factors regulate the development of multinucleated osteoclasts from recently replicated cells in vitro
... Osteoclasts mediate the process of bone resorption. However, little is known about the mechanisms that regulate the formation of either osteoclasts or osteoclast precursors. In contrast, colony-stimulating ...
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Granulocyte colony stimulating factors for febrile neutropenia prophylaxis following chemotherapy : systematic review and meta analysis
... There was a relatively high level of statistical heteroge- neity in the analyses as shown by the I 2 statistic, which ranged from 50-76%; this is likely to reflect the varia- tions between studies in factors such ...
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Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy: systematic review and meta-analysis
... There was a relatively high level of statistical heteroge- neity in the analyses as shown by the I 2 statistic, which ranged from 50-76%; this is likely to reflect the varia- tions between studies in factors such ...
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Immunological and functional differences between human type I and II colony stimulating factors
... of colony-stimulating factor (CSF) have recently been described in human tissues and cultured cell ...stimulate colony growth by day 7 but does do so by day 13 in cells sedimenting between ...
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In vitro and in vivo activation of endothelial cells by colony stimulating factors
... growth factors, granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage-colony-stimulating factor (GM-CSF), and to compare them with those elicited by prototypic ...
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The Effect of Granulocyte Colony Stimulating Factors (GCSF) on Expansion of CD34+ Hematopoietic Stem Cells
... (Granulocyte Colony Stimulating Factors) [5,6]. Colony Stimulating Factors (CSF), is hematopoietic growth factor, which plays a role in the regulation of bone marrow cell ...
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Nicarbazin Induce Oxidative Response and Colony Stimulating Factor Production in Mouse lung Cells In Vitro
... on colony stimulating factors in lung ...increase colony stimulating factors which may have affect on long term adverse reactions of ...
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The nutritional management of a patient with acute myeloid leukaemia
... It should be kept in mind that diet alone does not play a role in the management of neutropaenia. Antimicrobial prophylaxis, colony- stimulating factors, a protective environment (i.e. isolation), ...
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HEMATOPOIETIC GROWTH FACTORS AS BIOPHARMACEUTICALS: AN OVERVIEW
... clotting factors, thrombolytic agents, 7, 14 engineered cell or tissue-based products, 5 nucleic acid based drugs such as antisense drugs 9,10 and cytokines such as interleukins (ILs), interferons (INFs) and HGFs ...
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A study of molecules involved in the regulation of the growth of haematopoietic cells and heart muscle cells in culture
... Since Abboud et al., 1981 reported that giant cell tumour conditioned medium contained C.S.F.’s similar to those found in human placental conditioned medium, colony stimulating factors were isolated ...
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Effective stakeholder engagement: design and implementation of a clinical trial (SWOG S1415CD) to improve cancer care
... ASCO: American Society of Clinical Oncology; CER: Comparative effectiveness research; CSF: Colony stimulating factors; ESAG: External Stakeholder Advisory Group; FN: Febrile neutropenia;[r] ...
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Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony stimulating factor 1, and recombinant murine granulocyte macrophage colony stimulating factor on myelopoiesis in mice
... murine colony-stimulating factors (CSF) recombinant interleukin 3 (IL-3), natural CSF-1, and recombinant granulocyte-macrophage (GM) CSF were assessed in vivo for their effects on BDF1 mouse bone ...
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Effects of immunotherapy on mortality in neonates with suspected or proven sepsis: a systematic review and network meta-analysis
... granulocyte-colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF) and human antibodies to endotoxin (antilipo- polysaccharide), have been evaluated for ...
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Recombinant murine granulocyte macrophage colony stimulating factor has megakaryocyte colony stimulating activity and augments megakaryocyte colony stimulation by interleukin 3
... megakaryocyte colony formation. The dose-response curve for megakaryocyte colony induction with rGM-CSF showed plateau megakaryocyte stimulation at 9 ...megakaryocyte colony induction) was added to ...
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Myeloid-derived suppressor cells in hematological malignancies: friends or foes
... Granulocyte colony- stimulating factor; GM-CSF: Granulocyte-macrophage colony-stimulating fac- tor; G-PBSC: G-CSF peripheral blood stem cells harvest; GRFS: GVHD and relapse-free survival; ...
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Granulocyte colony stimulating factor (G CSF) and granulocyte macrophage colony stimulating factor (GM CSF) for sepsis: a meta analysis
... Conclusions While this meta-analysis demonstrated that G-CSF or GM-CSF therapy significantly increased the reversal rate from infection, it was not associated with a significant reductio[r] ...
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Transcriptional regulation of the mouse interleukin-5 gene in T lymphocytes
... A nother im p o rtan t feature of stable transfection is that few er copies of the exogenous gene are present per transfected cell com pared to the high concentration of supercoiled plasm id which can be achieved w ith ...
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Proliferation regulation of haematopoietic stem cells in normal and leukaemic haematopoiesis
... Factors regulating macrophage production and growth: Purification and some properties of the colony stimulating factor from medium conditioned by mouse L ceils.. Stephenson J, Axeirad A,[r] ...
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A screen for peptide agonists of the G CSF receptor
... Granulocyte-colony stimulating factor (G-CSF) is one the most widely employed protein drugs. It is mostly used for counteracting neutropenia in patients receiving chemotherapy [1], but also for stem cell ...
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