Colorectal cancer cell
Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction
... tumor cell growth at high concentrations (above 300 μ M); while low concentrations (100-200 μ M) promoted prolif- ...of cell mitochondrial membrane potential, reactive oxygen species (ROS) formation, ...
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miR 582 5P induces colorectal cancer cell proliferation by targeting adenomatous polyposis coli
... expression of target genes such as PGGT1B, LRRK2, and DIXDC1 [16]. Furthermore, Floyd et al. found that miR- 582-5P directly targeted caspase 3 (CASP3), caspase 9 (CASP9), and BIM, consequently influencing glioblastoma ...
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Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis
... primary colorectal cancer samples, no methylation was found in non-cancerous colonic tissue ...inhibited cell proliferation, migration, and invasion in colorectal ...suppressed ...
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Suppression of interferon gene expression overcomes resistance to MEK inhibition in KRAS-mutant colorectal cancer.
... Institute) of basal gene expression profiles for KRAS -mutant colorectal cancer cell lines. 688[r] ...
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Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer
... These cell lines were established from tumor specimens of primary colorectal cancers (CR9, CRC29, CRC47) and colorectal cancer liver metastases ...AmpliSeq Cancer Hotpot Panel v2 ...
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Prokineticin 2 (PROK2) is an important factor for angiogenesis in colorectal cancer
... study colorectal cancer among various malignant tumors owing to its high ...in colorectal cancer cell lines was examined, and the expression of PROK2 mRNA was found in many cell ...
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... human colorectal cancer cell lines DLD-1 and COLO 205 were maintained in RPMI- 1640 medium that supplemented with 10% fetal calf serum (FCS), 2 mM L-glutamine, 100 units/ mL penicillin, and 100 mg/mL ...
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MATRIX METALLOPROTEINASES AND THEIR ROLE IN BREAST CANCER: A MINI REVIEW
... liver cancer 3 (DLC3; also known as STARD8), is an integral component of the endosomal transport and sorting machinery ...breast cancer and benign breast ...breast cancer patients with lymph node ...
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<p>Grainyhead-Like Genes Family May Act as Novel Biomarkers in Colon Cancer</p>
... squamous cell carcinoma. 23 In colorectal cancer cells and tissues, the GRHL3 expression at both mRNA and protein levels was signi fi cantly ...repressed colorectal cancer cell ...
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miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts
... of colorectal cancer. However, what role miR-31 plays in colorectal cancer-associated fibroblasts (CAFs) has not been ...normal colorectal fibroblasts ...affected colorectal ...
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Therapeutic Inhibition of miR-4260 Suppresses Colorectal Cancer via Targeting MCC and SMAD4
... G1/S cell cycle transition and is highly expressed in well-differentiated cells, indicating its potential role as a tumor suppressor in both cell growth and differentiation [6, ...including ...
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Clinicopathological and prognostic significance of sialyl Lewis X overexpression in patients with cancer: a meta-analysis
... by cancer category (colorectal cancer, gastric cancer, lung cancer, breast cancer, head and neck squamous cell carcinoma, esophageal squamous cell carcinoma, oral ...
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Original Article N1,N3-bis(3-methoxysalicylidene) diethylenetriamine induces apoptosis in colon cancer HCT-116 cells through inhibiting Wnt1/β-catenin signaling pathway
... Abstract: Objective: The anti-cancer effect and mechanism of N1,N3-bis(3-methoxysalicylidene) diethylenetriamine (Valdien) in HCT-116 cells were assessed in this study. Methods: MTT was used to measure ...
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New trend in colorectal cancer in Germany: are young patients at increased risk for advanced colorectal cancer?
... Although screening for CRC is generally recom- mended in asymptomatic average-risk individuals start- ing at the age of 50 years, the screening options vary widely [22]. Amongst all screening options, colonoscopy has ...
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Ovarian cancer stem cells and targeted therapy
... SKOV3 cell lines were targeted by hyaluronic acid-paclitaxel (HA-TXL) which resulted in decreased tumor weight and nodules ...decreased cell viability through apoptosis induction in SKOV3 cell line, ...
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<p>MiR-326: Promising Biomarker for Cancer</p>
... the cell survival rate by MTT ...reduced cell viability compared with the negative control and mock transfection, and suggesting the underlying mechanism might be the blocking of MDR-related ...small ...
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Vorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects
... Twenty-three patients with relapsed and/or refractory mul- tiple myeloma were enrolled in the study. The objective response rate was 42%, including three partial responses among nine patients who were refractory to ...
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PubMedCentral-PMC4880997.pdf
... Results: African Americans (n = 81) were more likely to increase intakes of reduced-fat milk, vegetables, and fruit and decrease intakes of regular cheese, red meat, fried food, fast food, and fat (P , 0.05) than were ...
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Review Article Prognostic and clinicopathological significance of glucose-6-phosphate dehydrogenase in solid tumors: a meta-analysis
... for cell proliferation and provides anti-oxidative defense for cell ...to cancer invasion, metastasis, and resistance to anticancer thera- pies [9, ...
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Profile of nintedanib in the treatment of solid tumors: the evidence to date
... ovarian cancer with evidence of response but at high risk of further early recurrence, patients were randomized to receive either nintedanib 250 mg (n = 43) or placebo (n = 40), bid, continu- ously for 36 ...
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