colorectal cancers
Analysis of colorectal cancers for human cytomegalovirus presence
... of colorectal cancers, these results suggest that there is no evidence of a direct causal association between HCMV infection and induction of poorly or well- differentiated ...
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Colorectal Cancers in Mauritania: Clinical Aspects and Treatment
... of colorectal cancer conducted from 1 January 2008 to 31 December 2012 at the National Hospital Centre of Nouakchott (in internal medicine, hepato-gastroenterology, anatomypathology and general surgery ...
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The immunogenicity of colorectal cancers with high degree microsatellite instability
... in colorectal cancer include the release of mediators that suppress the function of tumour infiltrating lymphocytes: so-called "tumour ...infiltrating colorectal cancer have failed to demonstrate ...
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Molecular pathogenesis of sporadic colorectal cancers
... The genome-wide data hitherto reported were obtained by analyzing CRCs in the later stage. Even the initial events that determine the fate of tumor cells, whether hypermutated or non-hypermutated, have not been elu- ...
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Mutational profiling of colorectal cancers with microsatellite instability
... Microsatellite instability (MSI) is caused by defective mismatch repair in 15–20% of colorectal cancers (CRCs). Higher mutation loads in tumors with mismatch repair deficiency can predict response to ...
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Right- and left-sided colorectal cancers respond differently to cetuximab
... and is perfused by the superior mesenteric artery, whereas the left colon originates from the hindgut and is served by the inferior mesenteric artery [2]. Right-sided colon can- cers (RSCCs) are typically bulky, ...
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Prognostic factors after pulmonary metastasectomy of colorectal cancers: influence of liver metastasis
... Prognostic factors after pulmonary metastasectomy of colorectal cancers influence of liver metastasis RESEARCH Open Access Prognostic factors after pulmonary metastasectomy of colorectal cancers influ[.] ...
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Clinical characteristics of synchronous colorectal cancers in Japan
... independent cancers in cancer patients compared with the general population, and within them the exist- ence of patients with even higher propensity to multiple CRCs, further supports that genetic and ...
8
Screen-detected colorectal cancers are associated with an improved outcome compared with stage-matched interval cancers
... screen-detected cancers may influence future screening strategies that are based upon a tumour’s propensity to bleed, against those that endoscopically screen a ...
6
Evolving neoantigen profiles in colorectal cancers with DNA repair defects
... lung cancers associated with smoking habits have high levels of mutations [41, 42], whereas the deve- lopment of skin melanomas is correlated with UV light- mediated mutagenicity ...
22
Novel RNA variants in colorectal cancers
... have shown that such fusion transcripts have an impact on cancer biology, by regulating both replication and cell growth in cancer [16–19]. Chimeric mRNAs expressed in normal cells are sometimes overexpressed in cancer ...
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Somatic POLE exonuclease domain mutations in endometrial cancer : Insights into the biology of POLE-mutant tumors
... and colorectal cancers, we first examined whether these mutations were present in precursors of these ...endometrial cancers revealed four with a concomitant and spatially discrete area of ...
252
Insights into cancer mechanisms from genomic research on urological cancers
... these cancers execute a program for the cellular response to hypoxia achieving a Figure ...in colorectal cancers by mutations in intracellular components ...renal cancers (red). In other ...
5
Exploring the spatial patterns of three prevalent cancer latent risk factors in Iran; Using a shared component model
... of colorectal (ICD10 code C18-C20, C26), prostate (C61) and breast (C50) cancers in all provinces in 2009 that reported by No communicable Disease Management Centre of the ministry of Health and Medical ...
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PMS2-associated Lynch syndrome : the odd one out
... PMS2-mutant cancers is comparable to cMS mutations in MLH1-deficient and MSH2-deficient ...PMS2-mutant colorectal cancers develop through a similar pathogenetic mechanism, with a similar impact of ...
251
Original Article Activation-induced cytidine deaminase expression in colorectal cancer
... of colorectal cancer, and the nuclear expression of p53 protein in cancer ...71 colorectal adenomas and 122 sporadic colorectal cancers by ...122 colorectal cancers, ...in ...
6
Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision
... dMMR cancers and their lack of benefit from 5-FU therapy supports a non-adjuvant treatment approach in these patients, whereas pMMR could be considered as a risk factor to recommend adjuvant chemotherapy ...[19]. ...
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<p>Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review</p>
... to different tumors like CRC. In addition, RAD51 cru- cially contributes to the DSB repair across the homologous recombination (HR). It is notable that a major pathway to the DNA repair is the excision repair (ER) and ...
14
Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines
... diagnosed cancers; however, familial forms are believed to account for up to 30% of some ...hereditary cancers include colorectal cancer syndromes such as, Lynch Syndrome, Familial Adenomatous ...
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Advances in Therapeutic Targeting of Cancer Stem Cells within the Tumor Microenvironment: An updated Review
... The BET family, which are chromatin readers, interact with chromatin modifiers as well as enzymes to effect chromatin modification. Proteins containing bromodomains dock on acetylated histones [424, 425]. Consequently, ...
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