Colorectal tumours
Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways
... in tumours following anti-VEGF and anti- EGFR treatment is not well ...xenograft tumours (in presence of cetuximab, bevacizumab, and combination treatments) revealed alterations in proteins involved in ...
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The innervation and ultrastructure of blood vessels supplying benign and malignant colorectal tumours
... in colorectal carcinomas, suggesting that SP antagonists may be used in the treatment of tumours as their binding to vascular receptors may decrease tumour blood supply (Hennig et ...around ...
203
PRIMITIVE COLORECTAL TUMOURS AND METASTASES: A BRIEF REPORT ON 31 FEMALES WITH STAGE IV DISEASE
... Finally, our study analysed metastatic spread pattern in 31 advanced-stage female patients whose follow-up care included CT scans. CT remains the “workhorse” of follow-up imaging for the routine surveillance of ...
17
Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan cetuximab
... primary colorectal tumours mo- lecular profile in distant metastases is a current, but un- resolved issue in molecular and clinical ...in colorectal cancer patients indi- cated that the mutational ...
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Effects of Meat Intake Frequency and Polymorphic Cytochrome P450 2A6 Activity on Individual Colorectal Tumour Risk in a Japanese Cohort
... to colorectal tumours and smok- ing history, meat intake, and phenotypic P450 2A6 activity were assessed using odds ratios and 95% confidence intervals calculated from logistic regression models with ...
8
Podocalyxin-like protein expression in primary colorectal cancer and synchronous lymph node metastases
... having membranous expression, compared to TMA-based analyses (24,7% vs 8-13%) [7,8]. These findings are not unexpected, since PODXL is, in the vast majority of cases, overexpressed in a heterogenous fashion, preferrably ...
7
Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment.
... on colorectal tumours and matched PM and demonstrated that PM were more likely to have losses in 5q (26% vs 3%, p = ...primary tumours and hepatic metastases from 21 patients using targeted ...
10
Investigation of chromosomal abnormalities during colorectal tumour development by somatic cell hybrid and fluorescence in-situ hybridisation analysis
... with colorectal tumours not associated with PAP was chosen as a control population, to determine the significance of the ...the tumours arise) is epithelial in origin and may show a different ...
242
Calnexin, an ER induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer
... of tumours can lead to inadequate vascu- larisation resulting in decreased levels of oxygen, nutri- ents and glucose as well as altering intracellular calcium ...oncogenic tumours, protein overproduc- tion ...
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Enrichment of inflammatory IL 17 and TNF ? secreting CD4<sup>+</sup> T cells within colorectal tumors despite the presence of elevated CD39<sup>+</sup> T regulatory cells and increased expression of the immune checkpoint molecule, PD 1
... Dunne M, Ryan C, Tosetto M, Nolan B, Geraghty R, Winter DC, O_connell R, Hyland J, Doherty GA, Sheahan K, Ryan EJ and Fletcher JM(2016) Enrichment of inflammatory IL‐17 and TNF‐α secreting CD4+ T cells within ...
29
Feline Mast Cell Tumours
... Eosinophilia is common, but is a very non-specific finding in cats, and is also seen in lymphoma. Mastocytaemia (circulating mast cells) is NOT pathognomonic for mast cell disease (Piviani and others 2013). Mastocytaemia ...
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A Study of Agreement between Clinicoradiological and Histopathological Diagnosis of Bone Tumours and Tumour: Like Lesions with FNAC Study in Selected Cases
... Yoshikawa 27 and co-authors reported two examples of osteoblastoma associated with osteomalacia. Mirra 28 and co-authors described a case of osteoblastoma associated with severe systemic toxicity. Axial skeleton is ...
188
Diagnostic And Histogenetic Significance Of S 100 Protein In Oral Diseases
... both ectoder mal and mesenchymal maxillofacial lesions can be investigated with S odontogenic components show an elaborate 100 protein. But caution should be there in proliferation and mutual stimulation. interpreting ...
7
Histopathological study of CNS tumours and the role of GFAP expression in neuroepithelial tumours
... includes tumours of pineal parenchymal origin as well as astrocytomas, germ cell tumours, meningiomas, ...parenchymal tumours arise from the pineocytes or interstitial ...
153
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... Another reason for more overestimation than underestimation in our study was abnormal signals in perivesical fat in tumour location that were incorrectly identified as tumour invasion. For example, tumours were ...
5
Increased copy number at 3p14 in breast cancer
... unknown about the importance of amplifications of specific genes. In breast cancer, amplification of ERBB2 correlates with a worse prognosis [13] and amplification of C-MYC is associated with progression from carcinoma ...
9
Cystic Tumours of the Pancreas – a Rare and Diverse Type of Tumours
... Figure 1. CT, macro- and microscopic features of cystic tumours. 1a: Contrast enhanced CT reveal honey-comb features of serous cystic tumour; 1b: Per-operative macroscopic findings of serous cystic tumour in body ...
8
Relationship of patients' age to histopathological features of breast tumours in BRCA1 and BRCA2and mutation negative breast cancer families
... BRCA1-associated tumours have been found when such tumours are compared with sporadic cancers; these features include high tumour grade, negativity for oestrogen receptor (ER), overexpression of p53, ...
5
Support Vector Machines for the Classification of Early-Stage Breast Cancer Based on Radar Target Signatures
... of tumours used in this study includes four different models of tumours in four different sizes, similar to ...of tumours are spiculated, microlobulated, macrolobulated and smooth GRS, in which the ...
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RETRACTED ARTICLE: Comparative value of clinical, cytological, and histopathological features in feline mammary gland tumors; an experimental model for the study of human breast cancer
... Conclusion: The study concluded that cytology could be used as a quick, rapid, field diagnostic technique in combination with histopathology for the diagnosis of feline mammary tumors (FMTs). Our findings in feline MTs ...
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