Combined hyperlipidemia
Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment
... Familial combined hyperlipidemia (FCHL) is a complex genetic disorder characterized by variable phenotypic ex- pression and associated with obesity and insulin resistance ...of hyperlipidemia and ...
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The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion
... Though over 200 coding mutations within the LPL gene (MIM 609708) have been described, the role for common functional polymorphism of LPL, particularly in familial combined hyperlipidemia (FCH [MIM ...
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Impaired fatty acid metabolism in familial combined hyperlipidemia A mechanism associating hepatic apolipoprotein B overproduction and insulin resistance
... To establish whether insulin resistance and/or postprandial fatty acid metabolism might contribute to familial combined hyperlipidemia (FCH) we have examined parameters of insulin resistance and lipid ...
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Complex genetic contribution of the Apo AI CIII AIV gene cluster to familial combined hyperlipidemia Identification of different susceptibility haplotypes
... Familial combined hyperlipidemia (FCH) is a common ge- netic lipid disorder in Western societies. In a recent report (Dallinga-Thie, G.M., X.D. Bu, M. van Linde-Sibenius Trip, J.I. Rotter, A.J. Lusis, and ...
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Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia
... familial combined hyperlipidemia (FCHL) is unknown, but altered lipid turnover in peripheral tissues as well as hepatic overproduction of apolipoprotein B have been suggested as possible ...
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Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene
... Familial Combined Hyperlipidemia (FCH; MIM 144250) is the most frequent genetic hyperlipemia. It is characterized by a tendency towards the appearance of coronary disease before 60 years of age [4]. The ...
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Factors associated with postprandial lipemia and apolipoprotein A-V levels in individuals with familial combined hyperlipidemia
... 12. Valles V, Aguilar-Salinas CA, Gomez-Perez FJ, Rojas R, Franco A, Olaiz G, Rull JA, Sepulveda J: Apolipoprotein B and A-I distribution in Mexican urban adults: results of a nationwide survey. Metab Clin Exp 2002, ...
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Hyperlipidemia in Coronary Heart Disease II GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA
... of hyperlipidemia identified in this study has hitherto been poorly defined and has been designated as familial combined ...The combined disorder was shown to be genetically distinct from ...
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Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro A possible pathophysiologic explanation for familial combined hyperlipidemia
... We showed previously that net secretory output of apolipoprotein B apo B from cultured human hepatoma cells HepG2 is regulated by rapid reuptake of nascent lipoproteins before they have [r] ...
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Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein Cl
... Lipoprotein analysis revealed that VLDL were increased in HuCI Tg mice and, unlike HuCII Tg and HuCIII Tg mice, were significantly cholesterol enriched, consistent with the impairment of[r] ...
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Association of TCF7L2 Gene with Familial Combined Hyperlipidemia in Diabetes Mellitus Type 2 Females Iraqi Patients
... Genomic polymorphisms of transcription factor7 like 2 {TCF7L2} gene are scanned to be powerfully related to diabetes mellitus type 2 (DM2) in female Iraqi population. The point of this examination was to break down the ...
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Resolving the Genetic Etiology of Hypercholesterolemia in Familial Combined Hyperlipidemia
... The first sub-project of my second study tested whether the LDL-C genetic risk score was higher in Mutation Negative Familial Hypercholesterolemia (FH/M-ve) patients relative to Mutat[r] ...
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Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study
... Figure 1 Triglycerides, Total Cholesterol, and Total Cholesterol:HDL-C Ratio at Initial and Latest Clinic Visit in HTG Patients.. familial combined hyperlipidemia and is not routinely av[r] ...
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Original Article The diagnosis and treatment of familial hyperlipidemia combined with midsubstance Achilles tendinopathy in a young woman: a clinical case report
... Familial hyperlipidemia is primarily an inherited disorder characterized by an elevation of plasma low-density lipoprotein cholesterol and xanthomas at various ...familial hyperlipidemia and midsubstance ...
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Original Article Aerobic exercise combined with samara oil can improve hyperlipidemia by reducing PCSK9 and increasing LDLR
... of hyperlipidemia has very important practical sig- nificance for controlling the incidence and mor- tality of cardiovascular and cerebrovascular diseases ...
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ANTIHYPERLIPIDEMIC ACTIVITY OF GLORIOSASUPERBA
... DISCUSSION: Hyperlipidemia is characterized by elevated serum levels of total cholesterol (TC), lowdensity lipoprotein (LDL), very low density lipoprotein (VLDL) and decreased serum level of high density ...
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HYPERLIPIDEMIA: ITS MANAGEMENT AND INDUCTION
... The main aim of treatment in patients with hyperlipidemia is to reduce the risk of developing ischemic heart disease or the occurrence of further cardiovascular or cerebrovascular disease. Currently available ...
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Are patients with hyperlipidemia undertreated?
... of hyperlipidemia and coronary artery disease: on admission to hospital with coronary events, at which time we were able to esti- mate their risk of such ...
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Pediatric Aspects of Hyperlipidemia
... Data gathered in many prospective studies show a clear relationship between elevated serum cholesterol levels (over 200 mg/dl) and an increased risk of developing clinical coronary arter[r] ...
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Neonatal screening for hyperlipidemia
... One of the main objectives of recently published cord blood studies has been to establish the effectiveness of C and LDL in the detection at birth of an inherited form of hyperlipidemia [r] ...
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