competing endogenous RNA
Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22
... Long non-coding RNAs (lncRNAs) are involved in tumorigenesis. Metastasis- associated lung adenocarcinoma transcript 1 (MALAT1), an lncRNAs, is associated with the growth and metastasis of many human tumors, but its ...
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Long noncoding RNA <em>CRNDE</em> functions as a competing endogenous RNA to promote metastasis and oxaliplatin resistance by sponging miR-136 in colorectal cancer
... noncoding RNA (lncRNA) that is highly elevated in colorectal cancer and many other solid tumors but its functions on metastasis and oxaliplatin (OXA) resistance are ...a competing endogenous ...
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Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia
... unclear, competing endogenous RNA (ceRNA) hypothesis is a new approach to uncover the molecular pathology of ...non-coding RNA is involved in the pathogenesis of PE [11, 12], and further ...
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Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression
... Methods: Quantitative RT-PCR analysis was used to determine whether aberrant MEG3 expression was associated with GC patients pTNM stage and pM state. Furthermore, the effect of ectopic expression of MEG3 on cell ...
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Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway
... called competing endogenous RNA ...by competing with FOSL2 to bind miR-423-5p, resulting in increased migration and invasion of NPC through the Rho/Rac signaling ...
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An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma
... of RNA is one of the most important challenges facing biologists today, and long noncoding RNAs (lncRNAs) represent potential new biomarkers and drug ...a competing endogenous RNA (ceRNA) ...
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Genome-wide identification of long noncoding RNAs and their competing endogenous RNA networks involved in the odontogenic differentiation of human dental pulp stem cells
... and RNA, or they can interact with many proteins by forming complex secondary structures and regulate gene expression at the transcriptional, posttran- scriptional, and epigenetic levels [20, ...messenger ...
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The lncRNA myocardial infarction associated transcript-centric competing endogenous RNA network in non-small-cell lung cancer
... Background: The leading cause of death for cancer is lung cancer, of which the majority sub- type is non-small cell lung cancer (NSCLC). Recent studies have shown long non-coding RNAs are transcribed and contribute to ...
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LncRNA HOTAIR induces sunitinib resistance in renal cancer by acting as a competing endogenous RNA to regulate autophagy of renal cells
... intergenic RNA (HOTAIR) could serve as a biomarker to predict metas- tasis and poor prognosis in multiple tumors and act as a competing endogenous RNA (ceRNA) to up-reg- ulate microRNA-204 to ...
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The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer
... Notes: (A) hgc-27 cells were transfected with negative control, siTincr, or siTincr + miR-375 inhibitor and injected subcutaneously into 10 nude mice per flank. Surgical resections of hgc-27 xenograft tumors on week 4 ...
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CD44 3'-Untranslated Region Functions as a Competing Endogenous RNA to Enhance NK Sensitivity of Liver Cancer Stem Cell by Regulating ULBP2 Expression
... ceRNA: competing endogenous RNA; CRC: colorectal carcinoma cells; CRISPR: clustered regularly interspaced short palindromic repeats; CSC: cancer stem cells; CMV: Cytomegalovirus; Col1α1: Collagen ...
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The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA
... coding RNA (lncRNA) in ...that endogenous linc-223 localizes in the cytoplasm and acts as a competing endogenous RNA for miR- 125-5p, an oncogenic microRNA in ...
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Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs
... ceRNA: Competing endogenous RNA; DE ceRNA network: Subnetwork related to DE mRNA and DE lncRNA; DE lncRNAs: Differentially expressed lncRNAs; DE mRNAs: Differentially expressed mRNAs; GEO: Gene ...
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Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer
... Background: Long noncoding RNAs (lncRNAs) have been identified as a novel class of regulators implicated in diverse biological processes in human cancers. Currently, evidence have shown that SNHG6, a cancer-associated ...
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Long noncoding RNA SNHG6 mainly functions as a competing endogenous RNA in human tumors
... nucleolar RNA host gene 6 (SNHG6) has been reported in different cancers, such as hepatocellular carcinoma, colorectal cancer, and lung ...a competing endogenous ...
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Progress in Competing Endogenous RNA and Cancer
... of endogenous, non-coding 20 - 23 nucleotides RNA mo- ...non-coding RNA species, including small non-coding RNAs, pseudogenes, lncRNAs and circRNAs can act as miRNA “sponges” by sharing identical ...
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<p>Long Noncoding RNA <em>FGD5-AS1</em> Acts as a Competing Endogenous RNA on microRNA-383 to Enhance the Malignant Characteristics of Esophageal Squamous Cell Carcinoma by Increasing SP1 Expression</p>
... Methods: ESCC tissue samples and paired normal adjacent tissues were collected to quantify FGD5-AS1 expression by reverse-transcription quantitative PCR. The effects of FGD5-AS1 on ESCC cell proliferation, apoptosis, ...
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Long noncoding RNA H19 promotes transforming growth factor-β-induced epithelial–mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells
... Figure 8 h19 acts as a competing endogenous rna (cerna) that sequesters mir-370-3p. (A) Predicted duplex formation between the wild-type or mutant h19 and mir-370-3p. (B) Mir-370-3p expression levels ...
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<p>Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma</p>
... noncoding RNA (lncRNA) composed of more than 200 nucleotides in length and were commonly regarded as untranslational transcripts without protein- coding ...canonical competing endogenous RNA ...
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<p>Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer</p>
... LncRNA, a type of RNA with limited protein-coding ability, is previously viewed as transcriptional “ noise ” without biological functions. 14 Recently, lncRNAs are increasingly reported to be closely involved in ...
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