Competing endogenous RNAs (ceRNAs)
The gain and loss of long noncoding RNA associated-competing endogenous RNAs in prostate cancer
... of competing endogenous RNAs (ceRNAs), which offers a novel viewpoint to elucidate the mechanisms of ...of ceRNAs in ...gain ceRNAs in PC participated in cell cycle, and the loss ...
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<p>Long Non-Coding RNAs in Drug Resistance of Breast Cancer</p>
... non-coding RNAs (lncRNAs), which consist of more than 200 nucleotides, are a common type of ...as competing endogenous RNAs (ceRNAs), induce resistance in sensi- tive cells via ...
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C-Myc functions as a competing endogenous RNA in acute promyelocytic leukemia
... Recent reports have described a new post-transcriptional regulation that RNA transcripts can crosstalk with each other by competing for their common microRNAs. These RNA transcripts termed competing ...
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STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling
... years, competing endogenous RNAs (ceRNAs) have emerged as an important class of post-transcriptional regulator that alters gene expression through an miRNA-mediated mechanism [9, ...that ...
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Function and mechanism of long non-coding RNA Gm21284 in the development of hippocampal cholinergic neurons
... coding RNAs, has not been ...as competing endogenous RNAs (ceRNAs), which use binding sites with related miRNAs to bind miRNAs competitively and exert adsorption elimination, thereby ...
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Long non-coding RNAs in ovarian cancer
... It has been shown that diverse RNA molecules which harboring miRNA response elements (MREs) can act as competing endogenous RNAs (ceRNAs) [78]. CeRNA crosstalk represents a novel cluster of ...
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<p>Long Non-Coding RNAs Regulate Inflammation in Diabetic Peripheral Neuropathy by Acting as ceRNAs Targeting miR-146a-5p</p>
... non-coding RNAs, including microRNA (miRNA), long non-coding RNAs (lncRNAs), circular RNAs, and other regulatory non-coding ...Non-coding RNAs are demonstrated to play signi fi cant regulatory ...
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Competing endogenous RNA networks: tying the essential knots for cancer biology and therapeutics
... These competing endogenous RNAs (ceRNAs), or natural miRNA sponges, have an active role in regulating miRNA availability within the cell and form intertwined regulatory ...messenger ...
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The roles of lncRNA in hepatic fibrosis
... non‑coding RNAs; ECM: extracellular matrix; HSCs: hepatic stel‑ late cells; ceRNAs: competing endogenous RNAs; TGF‑β: transforming growth factor‑β; MALAT1: metastasis‑associated lung ...
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Qianggan extract improved nonalcoholic steatohepatitis by modulating lncRNA/circRNA immune ceRNA networks
... as competing endogenous RNAs (ceRNAs) or miRNA sponges, interacting with miRNAs in a manner that sequesters these molecules and reduce their regula- tory effect on target mRNAs ...as ...
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LBX2-AS1 up-regulated by NFIC boosts cell proliferation, migration and invasion in gastric cancer through targeting miR-491-5p/ZNF703
... ceRNA: Competing endogenous RNAs; ChIP: Chromatin immuno- precipitation; DANCR: Differentiation antagonizing non-protein coding RNA; DMEM: Dulbecco’s modified eagle medium; ECL: Enhanced ...
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Databases and resources for human small non-coding RNAs
... Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different levels ...
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Small RNAs in early mammalian development: from gametes to gastrulation
... Fig. 1. Biogenesis of microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs). (A) Canonical miRNAs are processed from long primary miRNAs ...
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Genome-wide identification of long noncoding RNAs and their competing endogenous RNA networks involved in the odontogenic differentiation of human dental pulp stem cells
... Many studies have shown that the expression of a num- ber of lncRNAs may be related to cell proliferation, apop- tosis, migration, and differentiation [17–19]. lncRNAs can regulate gene expression through a variety of ...
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Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs
... ceRNA: Competing endogenous RNA; DE ceRNA network: Subnetwork related to DE mRNA and DE lncRNA; DE lncRNAs: Differentially expressed lncRNAs; DE mRNAs: Differentially expressed mRNAs; GEO: Gene Expression ...
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Characterization of Viral and Human RNAs Smaller than Canonical MicroRNAs
... bases) RNAs, such as microRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs) participate in important cellular ...Piwi-interacting RNAs and transcription start site-associated ...
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<p>The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer</p>
... A recent study showed that GW182, a conserved factor, participates in circRNA degradation, 43 but further research is needed to con fi rm this mechanism. Another study found that circRNAs with N 6 -methyladenosine (m 6 A) ...
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Hsa_circ_0058124 promotes papillary thyroid cancer tumorigenesis and invasiveness through the NOTCH3/GATAD2A axis
... circular RNAs (circRNAs) represent a typical class generated by back- splicing and characterized by covalently closed loop structures that lack either 5′ to 3′ polarity and a polyadenylated ...
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<p>LINC00662 Long Non-Coding RNA Knockdown Attenuates the Proliferation, Migration, and Invasion of Osteosarcoma Cells by Regulating the microRNA-15a-5p/Notch2 Axis</p>
... Long non-coding RNAs (lncRNAs) are essential for the regulation of various cancers, including neuroblastoma, 9 breast cancer, 10 and OS. 11 The lncRNA LINC00662 (LINC00662) is 2085 bp long and is located at 19q11. ...
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Generation of measles virus defective interfering particles and their presence in a preparation of attenuated live-virus vaccine.
... These subgenomic RNAs, which interfered very efficiently with the replication of the endogenous standard genomes upon vaccine infection but showed a moderate interfering activity with a [r] ...
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