Composition of the Outer Membrane
LytM Proteins Play a Crucial Role in Cell Separation, Outer Membrane Composition, and Pathogenesis in Nontypeable Haemophilus influenzae
... Novartis Vaccines, Siena, Italy * Present address: Giuseppe Ercoli, University of Leicester, Leicester, United Kingdom. ABSTRACT LytM proteins belong to a family of bacterial metalloproteases. In Gram-negative bacteria, ...
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Mutagenesis of the rpoS gene involved in alteration of outer membrane composition
... Either the BglII downstream of the mutat- ed rpoS gene could be ligated into the BamHI site located next to the SalI site in the vector, subsequent digestion of SalI and BamHI minipr[r] ...
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Death upon a Kiss: Mitochondrial Outer Membrane Composition and Organelle Communication Govern Sensitivity to BAK/BAX-Dependent Apoptosis
... that membrane permeabilization may not be exclusively due to the formation of a proteinaceous pore, but there may be contributions of the lipid reorganization within the membrane that cause MOMP ( Figure 3 ...
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Understanding antibiotic resistance via outer membrane permeability
... The outer membrane of Gram-negative bac- teria performs the crucial role of providing an extra layer of protection to the organism without conceding the exchange of material required for sustaining ...the ...
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Outer Membrane Vesicle Production Facilitates LPS Remodeling and Outer Membrane Maintenance in Salmonella during Environmental Transitions
... The relative dearth of covalently modified LPS species in OMVs produced during the 5.8L-to-7.6H shift, the 5.8L-to-5.8L mock shift, and (to a lesser extent) the 7.6H-to-5.8L shift in con- ditions may reflect the ability ...
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E. coli Outer Membrane and Interactions with OmpLA
... The outer membrane of Gram-negative bacteria is a unique asymmetric lipid bilayer composed of phospholipids (PLs) in the inner leaflet and lipopolysaccharides (LPSs) in the outer ...coli outer ...
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Discrimination of outer membrane proteins with improved performance
... the composition of residue type i in the test protein, is the average composition of resi- due type i in the target group (OMPs, globular proteins or ...residue composition as ...
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Bioengineering bacterial outer membrane vesicles as vaccine platform
... T Outer membrane vesicles (OMVs) are naturally non-replicating, highly immunogenic spherical nanoparticles derived from Gram-negative ...the composition of the vesicles can easily be ...
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Outer membrane vesicles from cold-adapted antarctic bacteria
... As mentioned above, OMVs are secreted during the normal growth of bacteria. Additionally, we observed that OMVs from cold-adapted bacteria are not found in isolation but within a surrounding netlike mesh. It should be ...
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The role of outer membrane homeostasis in the virulence of gram-negative bacteria
... 4.2.13. PlpA is associated with Phosphatidylglycerol insertion into the OM The suppressor mutants highlighted that by creating null mutations in pathways and genes responsible for recycling or degrading OM phospholipids ...
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Virulent strain associated outer membrane proteins of Borrelia burgdorferi
... inner membrane fraction, and others were found exclusively associated with the inner ...protein composition of OMV changed significantly with successive in vitro cultivation of strain ...
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Sorting and membrane integration of mitochondrial outer membrane proteins
... observed. Strikingly, these alterations completely disappeared upon the introduction of pATOM36- HA into these cells (Figure 3D). To investigate the specificity of the complementation by pATOM36, we asked whether it can ...
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Outer Membrane of Avian Myeloblastosis Virus
... The antigen in question appeared to be located on the surface of the virion and could be distinguished from the type-specific virus envelope and the group-specific internal antigens of c[r] ...
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Immunobiology of Treponema hyodysenteriae outer membrane components
... Isolation and identification of Treponema hvodvsenteriae; aid to the diagnosis and treatment of swine dysentery, p. Investigation of a hemolysin produced by enteropathogenlc Trepo[r] ...
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Bacterial outer membrane vesicles and vaccine applications
... Kandolo, F. Bougoudogo, S. Sow and L. Bonte: Molecular Characterization of Invasive Meningococcal Isolates from Countries in the African Meningitis Belt before Introduction of a Serogroup A Conjugate Vaccine. PLoS One, ...
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Biochemical properties of the outer membrane of Treponema denticola
... Lane 1, molecular mass standards; lanes 2 through 4, LPS extracted from samples contain- ing 200 ,ug of protein of the NA moieties of the OMs of serovars a, b, and c, respectively; lanes[r] ...
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A study of outer membrane biogenesis in E. coli
... 137 4.1 Introduction The OM is vitally important and a distinguishing feature of Gram-negative bacteria. The OM is composed of phospholipids and LPS, as well as integral and peripheral outer membrane ...
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Structural basis for outer membrane lipopolysaccharide insertion
... Figure legends Figure 1 | Crystal structure of the LptD/E complex. The LptD barrel is shown in rainbow, the N-terminal strands coloured in blue, the C-terminal strands in red, and LptE in purple. E, P and OM represent ...
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Conserved Outer Membrane Protein of Neisseria meningitidis
... Nucleotide and amino acid sequence comparison of the ctrA genes from different meningococcal serogroup strains demonstrated that CtrA is a strongly conserved protein of the outer membran[r] ...
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Two-state folding of the outer membrane protein X into a lipid bilayer membrane
... the membrane protein OmpX folds under certain non-denaturing condition into a lipid bilayer as a two-state process, where folding, insertion and hydrogen bond formation synchronously follow a single exponential ...
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