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(1993) conducted a study for randomized controlled trials

Quality of randomized controlled trials reporting in the treatment of melasma conducted in China

Quality of randomized controlled trials reporting in the treatment of melasma conducted in China

... In China, internal Chinese medicine, acupuncture, moxi- bustion and combined therapies are also common in the treatment of melasma. To find the more efficient therapies, more and more randomized controlled ...

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Analyses of Cost Data in Economic Evaluations Conducted Alongside Randomized Controlled Trials

Analyses of Cost Data in Economic Evaluations Conducted Alongside Randomized Controlled Trials

... in randomized controlled trials. A search was conducted in the MEDLINE database as of September 2004 for all studies which included terms related to costs ...clinical trials (e.g., ...

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Misrepresentation of Randomized Controlled Trials in Press Releases and News Coverage: A Cohort Study

Misrepresentation of Randomized Controlled Trials in Press Releases and News Coverage: A Cohort Study

... This Study Done? In an ideal world, journal articles, press releases, and news stories would all accurately reflect the results of health ...of randomized controlled trials (RCTs—studies that ...

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Reporting of sex and gender in randomized controlled trials in Canada: a cross-sectional methods study

Reporting of sex and gender in randomized controlled trials in Canada: a cross-sectional methods study

... intervention, study design (cluster or individually randomized trial), sample size, and funding ...was conducted, what was done and how this was reported, drawing from items in the PRISMA-Equity ex- ...

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Systematic techniques for assisting recruitment to trials (START): study protocol for embedded, randomized controlled trials

Systematic techniques for assisting recruitment to trials (START): study protocol for embedded, randomized controlled trials

... host trials, we will ex- plore this in a meta-analytic ...across trials will be assessed using the I 2 ...between trials that might explain that ...of trials, but we will explore this issue ...

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Randomized Controlled Trials of Add-On Antidepressants in Schizophrenia

Randomized Controlled Trials of Add-On Antidepressants in Schizophrenia

... a study by Duinkerke and coauthors (1993) in which add-on ritanserin, a pure 5HT2 blocker devoid of antidepressive properties, improved negative symptoms in haloperidol-treated schizophrenia ...

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The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials

The effect of COPD severity and study duration on exacerbation outcome in randomized controlled trials

... As expected, discontinuations in COPD studies were high, especially as our patients predominantly had severe-to-very- severe COPD. We also found a higher discontinuation in the formoterol group, likely related to more ...

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Study designs of randomized controlled trials not based on Chinese medicine theory are improper

Study designs of randomized controlled trials not based on Chinese medicine theory are improper

... Wiklund et al. [50] reported a trial in which 384 sympto- matic postmenopausal women were assessed for the effects of P. ginseng on the quality of life and physiological parameters. Postmenopausal symptoms such as hot ...

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Effects of intense assessment on statistical power in randomized controlled trials: Simulation study on depression.

Effects of intense assessment on statistical power in randomized controlled trials: Simulation study on depression.

... A simulation study, based on three scenarios and several empirical data sets, estimated power gains of two- or fivefold pre-post-assessment. For each condition, data sets of various effect sizes were generated, ...

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Randomized Controlled Trials:

Randomized Controlled Trials:

... under study, for instance individuals, households, schools, or health clinics, a well-defined intervention with observable and measurable outcomes, and a random selection of the units into treated (those getting ...

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Analysis of Randomized Controlled Trials Peduzzi et al. Analysis of Randomized Controlled Trials

Analysis of Randomized Controlled Trials Peduzzi et al. Analysis of Randomized Controlled Trials

... the study protocol a priori, they may lead to bias because excluded subjects may differ from analyzed subjects regarding both measured and unmeasured ...of study subjects who deviate from the study ...

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OVERVIEW OF RANDOMIZED CONTROLLED TRIALS

OVERVIEW OF RANDOMIZED CONTROLLED TRIALS

... ABSTRACT Randomized controlled trials are considered to be the gold standard in clinical studies to establish level of evidence in medical ...groups. Randomized control trial (RCT) is most ...

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Bias in randomized controlled trials

Bias in randomized controlled trials

... compromise, have been widely publicized by the media during the past 3 months. Because of these results, patient advocacy groups are putting pressure on the government to make the new drug available as soon as possible. ...

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Discontinuation and Nonpublication of Randomized Clinical Trials Conducted in Children

Discontinuation and Nonpublication of Randomized Clinical Trials Conducted in Children

... clinical trials compared with adults, and a number of FDA policies aim to incentivize and increase the study of interventions in pediatric ...drug trials and the number of drug labels that contain ...

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Randomized Controlled Experiments Conducted With The ASSISTments Infrastructure

Randomized Controlled Experiments Conducted With The ASSISTments Infrastructure

... the study, they must correctly answer all six of the pretest items (items in test mode provide the student no feedback); this requires double the number of consecutive correct answers to place out of the ...

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1. Published Randomized Controlled Trials

1. Published Randomized Controlled Trials

... pilot study suggest that DBT can be provided effectively independent of the treatment’s developer and that larger efficacy and effectiveness studies are ...

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How necessary are randomized controlled trials?

How necessary are randomized controlled trials?

... Of course, well designed RCTs try their best to counter these difficulties. And poorly conducted historical studies will also be vulnerable to many of them. The point is only that conducting an RCT is no guarantee ...

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Diagnostic randomized controlled trials: the final frontier

Diagnostic randomized controlled trials: the final frontier

... robust study design to ensure accurate, safe, and effective diagnostic ...Properly conducted, randomized controlled trials are the gold standard for assessing the effectiveness and ...

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Randomized controlled trials: who fails run in?

Randomized controlled trials: who fails run in?

... this study, we analyzed data from the first 3 months of a long-term chemoprevention trial to identify baseline predictors of voluntary run-in failure (RIF) in three groups of ...in trials that involve ...

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Evidence Type Classification in Randomized Controlled Trials

Evidence Type Classification in Randomized Controlled Trials

... In particular, an evidence in a RCT is an obser- vation or measurement in the study (ground truth), which supports or attacks another argument com- ponent, usually a claim. Those observations com- prise side ...

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