Cone photoreceptor
Detection of airbag impact-induced cone photoreceptor damage by adaptive optics scanning laser ophthalmoscopy: a case report
... significant cone photoreceptor defects could be observed in the left eye at 14 months after the injury ...of cone defect corresponded to the area of the scotoma ...the cone mosaic was ...
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Outcome measure for the treatment of cone photoreceptor diseases: orientation to a scene with cone-only contrast
... Cone photoreceptor diseases (CPDs) are a subset of IRDs that preferentially affect day vision by causing im- paired clarity of vision, abnormal color vision, unstable fixation, and reduced extent of visual ...
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A moving wave patterns the cone photoreceptor mosaic array in the zebrafish retina
... Fig. 6. Models of photoreceptor patterning. (A) Schematic of the sequential induction and differentiation of photoreceptors in the eye imaginal disc of Drosophila larvae. The morphogenetic furrow is an indentation ...
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Automated measurements of human cone photoreceptor density in healthy and degenerative retina by region-based segmentation
... between cone photoreceptor cells that have low reflectance should cause overidentifica- tion because of the residual pixel noise or ambiguous tissues that are not cone photoreceptor ...of ...
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Koch, Mirja Annika (2016): The role of impaired cGMP homeostasis in cone photoreceptor degeneration. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... from cone photoreceptor dysfunction and is characterized by poor visual acuity, lack of colour discrimination and ...macular cone photoreceptors is ...the cone cyclic nucleotide-gated (CNG) ...
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Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival
... We discovered a novel light-activation of the insulin receptor (IR) signaling pathway in retinal rod photoreceptor neurons (Figure 1). Insulin receptors are confined to the plasma membrane of outer and inner ...
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High-resolution, in vivo imaging of the human cone photoreceptor mosaic
... The array of point structures in figure 4.10A is clearly visible. The measured point size is around 7 microns which is the expected diameter of an extrafoveal cone cell. As in the case of the ferret retina, a ...
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Cone photoreceptor macular function and recovery after photostress in early non-exudative age-related macular degeneration
... Three groups of subjects – young normal, older normal, and early non-exudative AMD subjects – were tested over a 2-year period. A subgroup consisting of four normal (two young and two old) and eight AMD subjects was ...
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Notch1 functions to suppress cone photoreceptor fate specification in the developing mouse retina
... The results presented here suggest that Notch1 is functionally upstream of Otx2 and Crx, and it acts to inhibit the expression of both genes in early RPCs (Fig. 7). Future studies will have to address the identity of the ...
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Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel–associated retinopathy
... Strikingly, we observed that the majority of patients (10 of 16; 62.5%) carried an additional heterozygous variant in CNGA3 (Table 1, Figure 1, and Supplemental Tables 1 and 2). Eight of these CNGA3 variants represent ...
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Visual pigments, oil droplets and cone photoreceptor distribution in the european starling (Sturnus vulgaris)
... Subjects were dark-adapted for at least 16 h before being killed. Under infrared illumination, the eyes were removed, hemisected and placed in a dissection medium comprising 340 mosmol kg −1 PBS and 11 mmol l − 1 D ...
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Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa
... then cone death triggered by dying rods ...underlying cone death are less well ...dominating cone death in rd10 mice yet with little impact on rods ...when cone loss was observed (Fig. 1). ...
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Optical influence of oil droplets on cone photoreceptor sensitivity
... Throughout vertebrate evolution, it is unclear whether oil droplets first appeared in the transparent or pigmented form; moreover, they may also have switched between states more than once. It also seems that because oil ...
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Cone photoreceptor oil droplet pigmentation is affected by ambient light intensity
... the cone responses, meant that the benefit of coloured oil droplets to vision was marginal at light levels approximating those around twilight ...the cone oil droplets of marsupial (metatherian) mammals and ...
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The Zebrafish pob Gene Encodes a Novel Protein Required for Survival of Red Cone Photoreceptor Cells
... to photoreceptor function with widespread patterns tude of light illumination (Dowling ...in photoreceptor mRNA splicing factors, molecules involved in fatty acid function, relatively little is known about ...
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Efficacy of valproic acid for retinitis pigmentosa patients: a pilot study
... represent cone photoreceptor ...in cone photoreceptor function: 16 of 29 (55%) patients felt it was easier to see during the period of VPA intake, whereas after cessation, eye discomfort was ...
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Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors
... Fig. 9. BMI1 is required for terminal differentiation, heterochromatin compaction and genomic stability of human cones. (A,B) IF analysis of hES cells differentiated for 21 days toward the cone ...
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Biophysical characterization of the photoreceptor synapse
... 14,000 cone bipolar ...to cone bipolar cells is about ...are cone bipolar cells (Euler and Wässle, ...of cone photoreceptors: one with spectral sensitivity peak at 360-365nm (the UV sensitive ...
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Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells
... These include the rod and cone photoreceptor cells in the outer nuclear layer ONL; the horizontal, bipolar and amacrine interneurons, plus the Müller glial cells in the inner nuclear lay[r] ...
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Optical coherence tomography findings in unilateral peripheral cone dysfunction syndrome: a case report
... peripheral cone dysfunction syndrome is not in the cone photoreceptor cells but in the horizontal cells and/or amacrine cells, in that cone photoreceptor cells in the foveola are ...
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