Connective Tissue Growth Factor:
Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy
... Steady-state connective tissue growth factor (CTGF) mRNA levels in renal cortex in rats after 24 to 30 weeks of diabetes mellitus Cruz Biotechnology, Santa Cruz, CA, USA) or anti- (DM) and in ...
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Connective tissue growth factor antagonizes transforming growth factor ?1/Smad signalling in renal mesangial cells
... 61, connective tissue growth factor, nephroblastoma overexpressed; CTGF, connective tissue growth factor; 1 CTGF, CTGF with domain 1 deleted; 2 CTGF, CTGF with ...
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Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice
... 1 Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan and 2 Division of Nephrology, Kobe City General Hospital, Kobe, Hyogo, Japan Connective tissue ...
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Plasma Levels of Connective Tissue Growth Factor in Children with Congestive Heart Failure
... ted plasma CTGF level in patients with CHF and correlated it with clinical parameters to evaluate its diagnostic and prognostic values in such children. We found that CTGF level was significantly elevated in patients ...
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Expression of Connective Tissue Growth Factor in the Human Liver with Idiopathic Portal Hypertension
... studies. Connective tissue growth factor (CTGF) levels in serum were examined in 76 patients with IPH, 84 pa- tients with hepatitis C virus infection (including those with cirrhosis), and 38 ...
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Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients
... fibrosis. Connective tissue growth factor (CTGF), a recently described profibrotic cytokine, acts downstream and in concert with TGF-β to stimulate the fibrotic process and is involved in the ...
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Serum connective tissue growth factor is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis
... Fig. 1 Diagnostic performance of serum connective tissue growth factor (CTGF) and synovial fluid CTGF. a Serum CTGF in the training cohort. CTGF concentration was detected in serum samples ...
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Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients
... fibrosis. Connective tissue growth factor (CTGF), a recently described profibrotic cytokine, acts downstream and in concert with TGF-β to stimulate the fibrotic process and is involved in the ...
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Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis
... [10], connective tissue growth factor (CTGF) appeared to be a potent strong biomar- ker in the infliximab-treated RA ...derived growth factor (PDGF) antiserum with a single ...
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CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes
... (Connective Tissue Growth Factor; CTGF ) is an essential mediator of ECM composition, as revealed through analysis of Ccn2 deficient ...
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Differential expression of connective tissue growth factor and hepatocyte growth factor in the vitreous of patients with high myopia versus vitreomacular interface disease
... of connective tissue growth factor (CTGF) and hepatocyte growth factor (HGF) in the vitreous of patients with high myopia, in comparison with those with a vitreomacular interface ...
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Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor (CCN2), transforming growth factor- β1, and vascular endothelial growth factor
... Although this study suggests that TGFb1 inhibition could be a tool to prevent or treat EPS, direct and chronic inhibition of systemic TGFb1 activity is probably not desirable in humans given the important role of TGFb1 ...
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Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction
... Connective tissue growth factor (CTGF; CCN2) plays a role in the development of diabetic nephropathy (DN). Urinary CTGF (uCTGF) is elevated in DN patients and has been proposed as a biomarker ...
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Accumulation of connective tissue growth factor+ cells during the early phase of rat traumatic brain injury
... transforming growth factor beta (TGF- β ) are key components of scar formation and blood-brain barrier ...modulation. Connective tissue growth factor (CTGF) is considered a ...
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Original Article Expression of connective tissue growth factor and periostin of wound tissue in patients with diabetes who had vacuum sealing drainage
... wound tissue of patients with diabetes; and investigate the expression of periostin and connective tissue growth factor in wound tis- ...and connective tissue ...
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Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells
... recombinant connective tissue growth factor (rCCN2/CTGF) Human ccn2/ctgf cDNA containing the entire coding region was inserted into the plasmid expression vector ...
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MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts
... CTGF: Connective tissue growth factor; CXCR4: CXC receptor 4; ECM: Extracellular matrix; ERK: Extracellular signal-regulated kinase; FCS: Fetal calf serum; HRP: Horseradish peroxidase; IgG: ...
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Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts.
... Abbreviations: CF, cardiac fibroblast; CCN2/CTGF, connective tissue growth factor; ECM, extracellular matrix; HK, housekeeping gene; IL-1, interleukin-1; MI, myocardial infarction; TGF [r] ...
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Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor
... Kayo Masuko 1* , Minako Murata 2 , Kazuo Yudoh 2 , Hiroyuki Shimizu 3 , Moroe Beppu 3 , Hiroshi Nakamura 4 , Tomohiro Kato 1 Abstract Background: The regulatory mechanisms of the expression of connective ...
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Original Article Correlation between overexpression of connective tissue growth factor, tumor progression, and clinical prognosis in endometrial cancer patients
... of connective tissue growth factor (CTGF), tumor progression, and clinical prognosis in patients with endometrial ...prognostic factor of endometrial ...
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