contractile response
Differential contractile response of critically ill patients to neuromuscular electrical stimulation
... of contractile response in the participants could be one cause for the incoherent and contradictory study results in NMES interventional trials throughout the past ...years. Contractile ...
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Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition
... enhanced contractile response to oxytocin in pregnant human myometrial tissue strips, which was inhibited by the IP antagonist ...Furthermore, contractile protein induction was dependent on the ...
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Enhanced Contractile Response and Protein Kinase Activation to Threshold Levels of β Adrenergic Stimulation in Hyperthyroid Rat Heart
... The contractile response measured as maximum rate of force development to a near threshold concentration of isoproterenol (1 nM) was enhanced in perfused interventricular septa from hyperthyroid (128±4% ...
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The Effect of Quinapril on the Aortic Contractile Response of Streptozotocin-Diabetic Rats
... Angiotensin-converting enzyme (ACE) inhibitors appear to correct many of the abnormalities associated with the vascular dysfunction found in diabetic patients. In this respect, quinapril is a unique ACE inhibitor with ...
5
Evaluation of the anti-ischemic effects of D-ribose during dobutamine stress echocardiography: a pilot study
... In this study, DR improved the contractile response to dobutmaine in myocardial segments with resting dysfunc- tion. Viable segments with resting dysfunction are pre- sumed to have repetitive stunning or a ...
6
Identification of a contractile function for renal medullary interstitial cells
... caused a slowly developing and dose-dependent reduction in RMIC surface area. ET-1 markedly increased the number and intensity of F-actin microfilament staining. ET-1- induced RMIC contraction was not altered by ...
7
Effects of NAD at purine receptors in isolated blood vessels
... NAD-mediated contractile response of the porcine mesenteric artery, suramin (100 µM; a P2 receptor antagonist) was employed; it had no significant effect except at the highest NAD concentration where ...
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Activated protein C increases sensitivity to vasoconstriction in rabbit Escherichia coli endotoxin induced shock
... the contractile response to PE, especially the increased sensitivity of aortic rings to PE when aPC is administered to non-endotoxinic ani- mals (the EC 50 of E+ rings of the aPC group is lower than that of ...
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Simulation of cell substrate traction force dynamics in response to soluble factors
... The phenomena of cell-substrate interaction have been widely used to examine the effect of cellular microenvironment in regulating cytoskeletal contractility as well as measure cellular contractile responses. The ...
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Selective changes in the α adrenoceptor mediated contraction in the senescent rat urinary bladder
... α-adrenergic contractile response to phenyle- phrine in the urinary bladder body and trigone, 2) the muscarinic contractile response to carba- chol in the body and ...
7
Measurement of cytoplasmic free Ca2+ concentration in rabbit aorta using the photoprotein, aequorin Effect of atrial natriuretic peptide on agonist induced Ca2+ signal generation
... mobilization of intracellular Ca2+. Atrial natriuretic peptide does not alter basal [Ca2+]i nor inhibit the [Ca2+]i transient induced by either histamine or angiotensin II, but blocks that induced by norepinephrine, and ...
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Eicosapentaenoic acid ethyl ester improves endothelial dysfunction in type 2 diabetic mice
... (Fig. 3b). Phenylephrine, an α-adrenergic receptor agonist, stimulates Ca 2+ entry through voltage-gated and store-operated Ca 2+ channels [28], and activates Ca 2+ -sensitization pathways such as protein kinase C (PKC) ...
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Aggregating platelets contract isolated canine pulmonary arteries by releasing 5 hydroxytryptamine
... the contractile response to ...affect contractile responses to platelets or ...the contractile response triggered by platelet aggregation; and (b) unlike in other blood vessels, the ...
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Effect of Subchronic Administration of Aqueous Artemisia annua Extract on a1-Adrenoceptor Agonist-Induced Contraction of Isolated Aorta in Rat
... relaxation response of extract-treated rats were ...the contractile response of aortic rings with endothelium to phenylephrine in extract-treated rats decreases ...relaxation response to ...
6
STUDY OF EFFECT OF ERYTHROMYCIN BASE ON GASTROINTESTINAL SMOOTH MUSCLES IN LABORATORY ANIMALS IN VITRO
... In isolated rat colon and guinea pig ileum, addition of erythromycin in high doses (100–1000 µM) did not per se caused any contraction itself. But erythromycin at all concentrations altered their response to ACh. ...
7
Direct effects of quercetin on impaired reactivity of spontaneously hypertensive rat aortae: comparative study with ascorbic acid
... In normotensive (WKY) tissues, treatment with l -NAME caused significant increases in the contractile responses to PE (Fig. 4) which was partially reversed by incubation of the tissues in either quercetin or ...
6
Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms
... Our data also revealed opposing actions of high PDBu on EFS-induced frequency response vs carbachol-induced concentration responses in isolated BMS. High PDBu in- duced increased sensitivity of responses to EFS as ...
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Insulin attenuates vasopressin induced calcium transients and a voltage dependent calcium response in rat vascular smooth muscle cells
... Insulin attenuates the contractile responses of vascular smooth muscle (VSM) to various agonists. Insulinopenic and insulin-resistant rats lack this normal attenuation of vascular contractile responses. To ...
8
Beta adrenergic receptor blockade of feline myocardium Cardiac mechanics, energetics, and beta adrenoceptor regulation
... and contractile state, and that prolonged beta- blockade may sensitize the myocardium to beta-adrenergic ...demonstrated contractile and energetic properties as well as dose-response behavior and ...
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Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel
... In the nervous system, TREK-1 was shown to control electrogenesis, differentiation, axonal migration, synapto- genesis, and neural response to temperature and mechan- ical stretch [1, 9, 13, 16, 19, 27, 31, 51]. ...
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