corneal epithelial stem cell
A clinical study on the outcome of tenoplasty in ocular chemical injuries.
... the corneal epithelial functions following limbal stem-cell ...goblet cell function of the conjunctiva can be improved by harvesting mucosal grafts from nasal ...
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Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation
... subpopulation A was originally CD34 + and subsequently contained a small number of CD45 + Cells. Despite this, subpopulation A did not produce hematopoietic colonies in specific HSC culture conditions (data not shown). ...
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Cellular therapy of corneal epithelial defect by adipose mesenchymal stem cell-derived epithelial progenitors
... All corneal imaging and measurements were conducted 3 days prior to injury (pre-operative) and weekly post- transplantation for a total of 4 ...the corneal clarity and haze formation from 0 to 4 under ...
13
A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium
... 5–6 cell layers, a thick stroma and an inner endothelium. The corneal epithelium is maintained by limbal epithelial stem cells (LESCs), in the ring-shaped limbus, which is a transition zone ...
8
siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy
... the cell lysates from cultures treated with the K12-Leu132Pro-9 siRNA, when compared with the K12 expression in NSC4 treated cultures ...limbal stem cell differen- tiation by quantifying expression ...
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Human induced pluripotent stem cell differentiation and direct transdifferentiation into corneal epithelial-like cells
... Adult stem cells reside within specialized microenvironments in which they are kept undifferentiated due to secreted signals from surrounding cells, cell-cell interactions and adhesion to ...
16
Anatomical location and culture of equine corneal epithelial stem cells
... of corneal epithelial differentiation– associated markers such as CK3 and ...human epithelial tissues, and is a stem cell ...basal cell activity and is also a stem ...
7
The PACAP-derived peptide MPAPO facilitates corneal wound healing by promoting corneal epithelial cell proliferation and trigeminal ganglion cell axon regeneration
... neural stem cells [49], TtT/GF cells [50], corneal epithelial cells and trigeminal ganglion cells, and promote the repair of corneal epithelial damage [51, ...promote corneal ...
16
Ocular stem cells: a status update!
... from stem cells for regenerative ...organ. Cell-based therapies using stem cells from the ciliary body, iris and sclera are still in animal experimental stages but show potential for replacing ...
12
A mathematical approach to human pterygium shape
... the corneal epithelium is to be maintained, cell loss must be balanced by cell replacement (X + Y = Z, where X stands for the proliferation of basal epithelial cells, Y stands for the ...
7
CD38 and CD157 Ectoenzymes Mark Cell Subsets in the Human Corneal Limbus
... the corneal limbus (1,28). However, an open issue in corneal regeneration is the lack of a dependable surface marker of the limbal stem cell population ...human corneal ...
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Ocular surface epithelial and stem cell development
... The corneal zone expresses a dramatic accumulation of large quanti- ties of globular metabolic enzyme, in particular aldehyde dehydro- genases and transketolase (Abedinia et ...the corneal domain (Wolosin, ...
11
Efficacy of cultivated corneal epithelial stem cells for ocular surface reconstruction
... limbal epithelial transplantation (CLET) in the clinical success ...entire corneal surface is covered with transplanted cultivated corneal epithelium (B) confirmed by fluorescein staining, with no ...
10
Limbal stem cell transplantation: current perspectives
... the corneal surface after an epithelial insult involves division, migration, and maturation of a specialized group of stem cells located in the ...limbal stem cell deficiency ...
10
Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis
... However, epithelial-like cells may be tumorigenic with cancer stem-like characteristics which may enhance SKOV3-Luc tumor growth and recapitulate in the original ...Both cell populations in this ...
14
Epithelial stem cell mutations that promote squamous cell carcinoma metastasis
... tumors that were both benign and malignant, we only observed the outgrowth of more aggressive SCCs and BSCCs following serial passage. In addition, the transplanted tumors frequently exhibited EMT-mediated progression. ...
16
Stem Cell Research: A Novel Boulevard towards Improved Bovine Mastitis Management
... the epithelial cells of the alveoli, ducts and cisterns of the entire ...(secretory epithelial cells) ...luminal/secretory epithelial cells mainly express the CK18, CK19, CK7 and CK8 ...mammary ...
12
Ocular surface squamous neoplasia in HIV-infected patients: current perspectives
... and corneal epithelial tumors including dysplasia, carcinoma in situ, and invasive ...of corneal, scleral, and orbital invasion, advanced-stage T4 tumors, higher need for extended ...
13
Lgr proteins in epithelial stem cell biology
... adult stem cell markers with essential roles in regulating stem cell activity in various adult tissues (Barker et ...of epithelial stem cell biology in a variety of ...
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Comparison of single-step reverse transepithelial all-surface laser ablation (ASLA) to alcohol-assisted photorefractive keratectomy
... The primary finding of this study was that the use of this technique offers patients significantly reduced early postoperative pain (with a mean main score of 0.9 versus 2.6 at the third postoperative day), reduced ...
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