Cortical dysplasia
MRI, Magnetoencephalography, and Surgical Outcome of Oligodendrocytosis versus Focal Cortical Dysplasia Type I
... Surgical Treatment and Outcome There were no significant differences in invasive monitoring (P ⫽ .09), extent of resection (unilobar versus multilobar versus hemispherectomy) (P ⫽ .37), or location of the operation ...
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Abnormal Blood Oxygen Level–Dependent Fluctuations in Focal Cortical Dysplasia and the Perilesional Zone: Initial Findings
... Focal cortical dysplasia is a common cause of intractable epilepsy for which neurosurgery is an ...focal cortical dysplasia lesion on structural brain images may not necessarily reflect the ...
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Second hit mosaic mutation in mTORC1 repressor DEPDC5 causes focal cortical dysplasia–associated epilepsy
... focal cortical dysplasia (FCD), brain somatic muta- tions in genes belonging to the mechanistic target of rapamycin complex 1 (mTORC1) pathway are increasingly reported (2, 3), especially activating somatic ...
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Radiologic and Pathologic Features of the Transmantle Sign in Focal Cortical Dysplasia: The T1 Signal Is Useful for Differentiating Subtypes
... abnormal cortical development: direct electrocortico- graphic-histopathologic ...focal cortical dysplasia: best criteria for clinical ...focal cortical dys- plasia in infants: some MRI lesions ...
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Clinical and immunohistochemical characteristics of type II and type I focal cortical dysplasia
... architectural cortical dysplasia in cortex, which presented as tangential dyslamination (Figure 2a) and radial disorganization (Figure ...architectural cortical dysplasia and cytoarchitectural ...
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Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II
... focal cortical dysplasia was suggested in brain magnetic resonance imaging (MRI): focal changes in the cortical thickness, signal increase (mainly on T2FLAIR and T2WI sequences), gray-white matter ...
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Focal cortical dysplasia of Taylor, balloon cell subtype: MR differentiation from low grade tumors
... solitary cortical tuber in two patients without clinical stigmata of tuberous sclerosis describes subcortical signal changes without associated radial white matter bands ...
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MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study
... MATERIALS AND METHODS: The morphometric analysis program and normalized FLAIR signal intensity analysis were applied to retro- spectively analyze the MR imaging data of 58 patients with histopathologically confirmed type ...
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Advanced MR Imaging of Cortical Dysplasia with or without Neoplasm: A Report of Two Cases
... cal dysplasia and those of Li et al (10) and Kuzniecky et al (4) may be related to sampling error associated with their use of spectroscopic voxel sizes, which ex- ceeded the size of the actual metabolic ...
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Identification and immunophenotype of abnormal cells present in focal cortical dysplasia type IIb
... Focal cortical dysplasia was first defined by (Taylor et ...normal cortical lamination with large bizarre neurons and ...of cortical lamination, and type Ib additionally presented ...
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Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex
... Background: Focal cortical dysplasia type IIb (FCD IIb) and tuberous sclerosis complex (TSC) are well-recognized causes of chronic intractable epilepsy in children. Accumulating evidence suggests that ...
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Microscopic cortical dysplasia in infantile spasms: evolution of white matter abnormalities
... Several studies (13–18) have described in detail the substantial and predictable signal changes in the MR of the developing human brain during the first 2 years of life. These changes in the MR signal pattern of the ...
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Case Report Encephalomalacic dysplastic mass lesion associated with vascular abnormalities in an elderly man. Is this “acquired” focal cortical dysplasia?
... the cortical and subcortical encephalomalacic features to be presumably “secondary” to the underlying/ associated vascular ...preexistent cortical dysplasia with secondary ischemic changes; however, ...
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Cerebellar Cortical Dysplasia: MR Findings in a Complex Entity
... cerebellar cortical dysplasias may result from different causes, both genetic and ac- ...cerebellar cortical dysplasia is associated with other cerebral malformations and immunohis- tological ...
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Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy
... Focal cortical dysplasia (FCD) is a common cause of pharmacologically-intractable epilepsy, however, the precise mechanisms underlying the epileptogenicity of FCD remains to be ...
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Clinical Features of a Series of Non-Surgical Patients with Focal Cortical Dysplasia and Epilepsy
... focal cortical dysplasia and epilepsy are surgical or pathological series of pediatric ...focal cortical dysplasia by standardized ...with cortical dysplasia are poor surgical ...
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Ultra High Field Targeted Imaging of Focal Cortical Dysplasia: The Intracortical Black Line Sign in Type IIb
... Ultra-high-field MR imaging offers an enhanced spatial reso- lution reaching microscopic values due to its high signal-to-noise ratio, allowing the different components within the cortex to be visualized, especially ...
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Disorganization of neocortical lamination in focal cortical dysplasia is brain-region dependent: evidence from layer-specific marker expression
... A detailed characterization of architectural distur- bances has recently become possible by using layer- specific markers which specifically label subsets of cortical neuron types with restricted laminar ...
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<p>Histological type of focal cortical dysplasia is associated with the risk of postsurgical seizure in children and adolescents</p>
... Based on the results of the presurgical evaluation, deci- sions regarding the type and extent of surgery were made for each individual patient after a multidisciplinary case discussion. The resection areas included the ...
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Optimizing MR Imaging Detection of Type 2 Focal Cortical Dysplasia: Best Criteria for Clinical Practice
... RESULTS: Only 42 patients (59%) had positive MR imaging findings. In this group, a combination of at least 3 criteria was always found. Subcortical signal changes were constant. Three characteristic signs ...
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