Cortical Neurons
Effect of Interleukin 1Beta (IL 1β) on the Cortical Neurons Survival and Neurites Outgrowth
... Insults to the brain are known to cause a myriad of downstream effects, including the release of cytokines by astrocytes and resultant reactive gliosis [7] [8]. Cytokines are thought to be a major mediator of reactive ...
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Original Article Stability and Autolysis of Cortical Neurons in Post- Mortem Adult Rat Brains
... the cortical neurons in adult brains for 24 hours at room temperature (+20ºC) after cardiac ...cerebral neurons in the first 6 hours after warm cardiac arrest, in agreement with previous studies in ...
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Uptake and mitochondrial dysfunction of alpha synuclein in human astrocytes, cortical neurons and fibroblasts
... astrocytes, cortical neurons and skin-derived fibroblasts, human α-syn was incubated overnight at 37°C to form oligomers and then labelled with Alexa Fluor 488 (Invitrogen) as per the manufacturer’s ...
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C Jun N terminal kinases/c Jun and p38 pathways cooperate in ceramide induced neuronal apoptosis
... ceramide-induced cortical neuron apoptosis, we overexpressed a DNc-Jun in primary cortical ...protects cortical neurons against ceramide-induced ...sympathetic neurons (Ham et ...
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Diversity of intrinsic frequency encoding patterns in rat cortical neurons : mechanisms and possible functions
... single neurons in primary and secondary somatosensory cortices of monkeys in vivo have shown that their firing rate can increase, decrease, or remain constant in different cells, as the external stimulus frequency ...
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Extracellular cathepsin L stimulates axonal growth in neurons
... The current study indicated for the first time that extracellular cathepsin L stimulates axonal growth, but not dendritic growth, in cortical neurons and spi- nal cord neurons (Fig. 1). Since there ...
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Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis
... migrating neurons stabilizes their cytoskeleton, anchors them to the marginal zone and promotes somal translocation (Chai et ...generated cortical neurons destined to superficial layers of the ...
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Brain Infection by Neuroinvasive but Avirulent Murine Oncornaviruses
... granule neurons is widespread and highly productive (23), degenerative changes are not observed, even when viewed ...The neurons which do undergo degenerative changes are not infected (16, 19, ...cerebellar ...
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Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons
... superficial neurons are specified much earlier and are encoded in cortical progenitors at the time of deep- layer neuronal generation (Franco et ...of cortical neuronal fate is complex, and involves ...
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Critical roles of αII spectrin in brain development and epileptic encephalopathy
... rat neurons expressing EIEE5 SPTAN1 mutations are also present in human neurons, we generated induced pluripotent stem cells (iPSCs) from fibroblasts obtained from 2 control indi- viduals and an EIEE5 ...
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Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons
... generated neurons that start to migrate before ...generated neurons follow thereafter and may increasingly use radial glia- guided migration (Nadarajah and Parnavelas, 2002; Sanada et ...generated ...
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Apoptosis plays an important role in experimental rabies virus infection.
... of neurons in topographic regions with apoptotic morpho- logic changes and immunostaining for rabies virus antigen ...of neurons developed 5 days after inoculation and gradually increased as the disease ...
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Astrocytes Prevent Ethanol Induced Apoptosis of Nrf2 Depleted Neurons by Maintaining GSH Homeostasis
... silenced neurons by staining with MCB followed by FACS ...silenced neurons showed a significant increase in GSH levels when compared to Nrf2 downregulated neu- rons (siNrf2 + ETOH ...primary cortical ...
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Temporal Dynamics of Cortical Adaptation
... of cortical response recovery from adaptation, lies in the range of 100 and 400 ms for recovery from a single-pulse ...excitatory neurons (Petersen, ...
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The G protein coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex
... Fig. 1. GPRC5B expression in the developing mouse brain. (A) Expression of Gprc5a, Gprc5b and Gprc5c was analysed by RT-PCR using cDNAs derived from mouse cortical progenitor cells and the tissues indicated. (B) ...
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The COPII cargo adapter SEC24C is essential for neuronal homeostasis
... postmitotic neurons, unlike professional secretory cells in other tissues, are exquisitely sensitive to loss of ...postmitotic neurons in the murine cerebral ...postmitotic neurons was further ...
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Significance of the Thalamic Reticular Nucleus GABAergic Neurons in Normal and Pathological Activity of the Brain
... between neurons of the thalamic reticular nucleus (TRN) and relay neurons of the thalamic nuclei was ...TRN neurons was shown to abate activity of relay ...TRN neurons is supposed to occur ...
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Injury induced plasticity in primary neuronal culture and the mature brain
... to neurons, at any of the concentrations ...that cortical neurons are capable of tolerating up to 100nM of Epo D with no evident negative consequences on neuronal ...
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Fructus mume extracts alleviate cognitive impairments in 5XFAD transgenic mice
... One week after the behavioral experiments, 9 mice per group were decapitated and the hippocampal or cortical samples were dissected and snap-frozen. For the total protein extracts, individual tissue samples were ...
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Proteomic Analysis Reveals Selective Impediment of Neuronal Remodeling upon Borna Disease Virus Infection
... in neurons, including factors regulating the local transport or modification of mRNA and nuclear proteins involved in transcriptional regulation and chromatin ...
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