Corticotropin-releasing factor
Corticotropin releasing factor Mechanisms to inhibit gastric acid secretion in conscious dogs
... of corticotropin-releasing factor (CRF) is found in regions of the central nervous system that modulate autonomic responses, including gastrointestinal ...
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Rodent models of human alcoholism : implications for a role of neuropeptide Y and corticotropin releasing factor
... Rodent models of alcoholism have been integral in discovering candidate genes and neurochemicals involved in this disease. Two promising candidates include neuropeptide Y (NPY) and corticotropin releasing ...
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Immunoreactive corticotropin releasing factor in human plasma
... Plasma immunoreactive corticotropin-releasing factor (I-CRF) levels were determined by using a human CRF radioimmunoassay and an immunoaffinity procedure. The basal plasma I-CRF level in normal ...
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Epidermal growth factor acts as a corticotropin releasing factor in chronically catheterized fetal lambs
... purified mouse EGF or synthetic ovine corticotropin releasing factor (CRF) to chronically catheterized fetal sheep. Both CRF and EGF were associated with increases in plasma immunoreactive ACTH ...
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Human corticotropin releasing factor plus lysine vasopressin test during glucocorticoid therapy
... 1.0 micrograms/kg body wt human corticotropin-releasing factor (hCRF) and 0.005 IU/kg body wt lysine vasopressin (LVP) were administered in a bolus dose to patients receiving daily or alternate-day ...
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ANTIDEPRESSANT ACTIVITY OF THYMOQUINONE POSSIBLY THROUGH INVOLVEMENT OF CORTICOTROPIN RELEASING FACTOR
... Depression and stress have a strong interlinking and have been well established. A key factor in response to stress is the neuropeptide corticotropin-releasing factor (CRF) [4]. CRF and its ...
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Continuous administration of synthetic ovine corticotropin releasing factor in man Physiological and pathophysiological implications
... The continuous 24-h infusion of a maximally stimulating dose (1 micrograms/kg per h) of ovine corticotropin-releasing factor (CRF) in man caused a modest elevation of plasma cortisol (17.2 +/- 1.4 ...
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Effect of synthetic ovine corticotropin releasing factor Dose response of plasma adrenocorticotropin and cortisol
... Synthetic ovine corticotropin-releasing factor (CRF) was administered to normal male volunteer subjects as an intravenous bolus or 30-s infusion. Doses of CRF ranging from 0.001 to 30 micrograms/kg ...
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Arginine vasopressin potentiates adrenocorticotropin release induced by ovine corticotropin releasing factor
... Arginine vasopressin (AVP) stimulates ACTH release in man and acts synergistically with synthetic ovine corticotropin-releasing factor (oCRF) in vitro. This study was designed to examine in man the ...
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Female-biased sexual dimorphism of corticotropin-releasing factor neurons in the bed nucleus of the stria terminalis
... Corticotropin-releasing factor (CRF) neurons, in the para- ventricular nucleus of the hypothalamus (PVH), play a piv- otal role in the regulation of hypothalamic-pituitary-adrenal axis and control ...
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Activation of the corticotropin releasing factor receptor from the basolateral or central amygdala modulates nociception in guinea pigs
... Corticotropin-releasing factor (CRF) is a peptide that is released from the hypothalamus into widespread areas of the brain. Evidence has suggested that CRF is involved as a neuromodulator outside of ...
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Insulin induced hypoglycemia stimulates corticotropin releasing factor and arginine vasopressin secretion into hypophysial portal blood of conscious, unrestrained rams
... of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) secretion in hypophysial portal blood (HPB) during IIH have been diversely ...main factor triggering ACTH release, and ...
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Studies of the secretion of corticotropin releasing factor and arginine vasopressin into the hypophysial portal circulation of the conscious sheep II The central noradrenergic and neuropeptide Y pathways cause immediate and prolonged hypothalamic pituitary adrenal activation Potential involvement in the pseudo Cushing's syndrome of endogenous depression and anorexia nervosa
... Studies were performed to determine the effects of intracerebroventricular norepinephrine (NE) or neuropeptide Y (NPY) on the ovine hypothalamic-pituitary-adrenal (HPA) axis. NE (50 micrograms) increased mean ...
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Noradrenergic inhibition of canine gallbladder contraction and murine pancreatic secretion during stress by corticotropin releasing factor
... inhibited cholecystokinin-8 (CCK)- and meal-induced gallbladder contraction, and restraint stress inhibited basal and CCK/secretin-stimulated pancreatic secretion. These inhibitory responses were mimicked by cerebral ...
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Effect of the long term administration of corticotropin releasing factor on the pituitary adrenal and pituitary gonadal axis in the male rat
... ovine corticotropin-releasing factor (oCRF) was measured in adult male ...the releasing factor, followed by a decrease to lower, but still above control, ...Additionally, ...
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Corticotropin releasing factor receptors and stress related alterations of gut motor function
... decades, corticotropin-releasing factor (CRF) signaling pathways have been shown to be the main coordinators of the endocrine, behavioral, and immune responses to ...
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R : Actin cytoskeleton–dependent regulation of corticotropin releasing factor receptor heteromers
... However, contrary to our prediction, stimulation of cells expressing CRF1R+CRF2βRΔSP with Ucn1 did not result in significantly different Ca2+ responses than those observed in cells expre[r] ...
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Corticotropin-releasing Factor Receptor 2 Mediates Sex-Specific Cellular Stress Responses
... nuclear factor-κB (NF-κB), calcium- signaling defects, endoplasmic reticulum (ER) stress defects and dysfunctional secre- tory pathways have all been identified mechanisms that contribute to the patho- genesis of ...
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Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer’s disease-like tau hyperphosphorylation
... Our results indicated that chronic noise exposure induces elevated expression of CRF and CRFR1 mRNA and pro- tein in the rat hippocampus; further, we show a delayed increase in CRFR2 mRN[r] ...
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Corticotropin releasing factor receptor type 1 signaling in epilepsy and traumatic brain injury
... Disturbances in homeostasis due to stressors are thought to mitigate the onset of depression or anxiety (de Kloet et al., 2005). The physiological mechanisms following stressful stimuli involve various brain regions, ...
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