CREB (cAMP response element binding protein) binding protein
Adenosine A2Breceptors induce proliferation, invasion and activation of cAMP response element binding protein (CREB) in trophoblast cells
... intracellular cAMP [4,5,21]. cAMP is a secondary messenger involved in intracellular signal transduction, and also in the activation of protein ki- ...nases. cAMP-dependent protein ...
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Diet change and exercise enhance protein expression of CREB, CRTC 2 and lipolitic enzymes in adipocytes of obese mice
... The cAMP-response element-binding protein (CREB)- regulated transcription coactivator (CRTC) family com- prises three functionally diverse proteins: CRTC 1, 2 and ...with ...
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Analysis of hepatic gene transcription in mice expressing insulin insensitive GSK3
... insulin response element) that can be regu- lated by several transcription factors such as members of the Forkhead (FOXO) family ...phosphoinositide-dependent protein kinase-1) [16] and ...regulatory ...
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Models of buffering of dosage imbalances in protein complexes
... with binding partners forming an oligomer ...the cAMP response element binding protein (CREB-binding protein or CBP) and the ac- tivator for thyroid hormone ...
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Tong Luo Jiu Nao ameliorates Aβ1–40 induced cognitive impairment on adaptive behavior learning by modulating ERK/CaMKII/CREB signaling in the hippocampus
... surface protein receptors and intracellular signal transductions, including acetylcholine (Ach), glutamate (Glu), muscarinic acetylcho- line receptors (mAChR), N-methyl-D-aspartic acid (NMDA) receptors, ...
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Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip
... cAMP response element binding protein phosphorylation PC 12 cells were starved for 5 h and then challenged with NGF and CM extract for 0, 2 or 5 ...anti-phospho-cAMP ...
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The nuclear transportation routes of membrane-bound transcription factors
... regulatory element-binding protein (SREBP), plant bZIP TF family protein bZIP28 and several activating transcription factor (ATF)/cAMP response element-binding ...
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MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction
... immuno-precipitation; CREB: cAMP response element-binding protein; Crh : corticotropin releasing hormone gene; Dnmt: DNA methyl-transferases; ELS: early life stress; Fos: FBJ ...
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Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target
... zipper; cAMP, cyclic AMP; CBP, CREB-binding protein; ChiP, chromatin immunoprecipitation; CRE, cAMP response element; CREB, cAMP response ...
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Antidepressant like effects of acupuncture involved the ERK signaling pathway in rats
... The protein levels of ERK1/2, phosphor (p)-ERK1/2, cAMP response element-binding protein (CREB), p-CREB and brain-derived neurotrophic factor (BDNF) in the ...
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The CRE-Binding Protein dCREB-A Is Required for Drosophila Embryonic Development
... Another CRE- binding protein, CREMa, may downregulate CAMP- stimulated CREB activity by forming heterodimers with CREB (FOULKES et al. Ultimately, we would like to unde[r] ...
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Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice
... sequesters CREB-binding protein (CBP), an important activator of CREB, to de- crease the expression of CREB target genes [33, ...hanced CREB-dependent transcription of BDNF that ...
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The Role of CREB in the Liver and Adipose Tissue
... of CREB, which in addition to CREB are the activating transcription factor 1 (ATF1) and cAMP- responsive element modulator (CREM), and these two proteins can also mediate transcriptional ...
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α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis
... biopolymers. cAMP plays as a key second messenger in the generation of heavily pigmented melanosomes ...G protein-coupled receptors (GPCRs)-mediated activation of adenylate cyclase ...[6]. cAMP binds ...
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Anxiolytic effects of Formononetin in an inflammatory pain mouse model
... and CREB binding protein was ...and CREB binding protein (CBP, PDB code: 5CGP) structures were downloaded from the RCSB Web site ...the protein-ligand ...
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Protein-protein interactions of transcription factor CREB 1
... (CREB Binding Protein, see Chapter 1) (Chrivia et ...of CREB and which has since been shown to behave as a transcriptional co-activator of CREB (Arias et ...a CREB-interacting ...
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The protective effect of fermented Curcuma longa L on memory dysfunction in oxidative stress induced C6 gliomal cells, proinflammatory activated BV2 microglial cells, and scopolamine induced amnesia model in mice
... the cAMP-response elem- ent binding protein (CREB) plays a critical role by turning on the molecular switch of the brain-derived neurotrophic factor (BDNF) for long-term memory for- ...
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Steinert, Daniela (2013): Untersuchungen zur Regulation und Funktion der Cyclooxygenase-2 in Nierenmarkszellen unter osmotischem Stress. Dissertation, LMU München: Medizinische Fakultät
... To monitor activation of potential signaling pathways, MDCK cells were transfected stably with appropriate reporter constructs based on secreted alkaline phosphatase (SEAP; Clontech, Palo Alto, CA). (1) In pCRE-SEAP ...
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Hypoxia-induced responses by endothelial colony-forming cells are modulated by placental growth factor
... key element in HIF1α-mediated PlGF upregulation [44, ...and CREB are also stabilised under low oxygen conditions, and may play a role in PlGF upregu- lation [41, 42, 45, ...
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Protein phosphatase 2A is a negative regulator of IL 2 production in patients with systemic lupus erythematosus
... PP2Ac mRNA is increased in lupus T cells and correlates with PP2Ac protein levels. T cell PP2Ac mRNA levels were assessed using real-time RT-PCR as described in Methods. PP2Ac protein levels were determined ...
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