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Cryptococcal Meningitis

Cryptococcal meningitis: A neglected NTD?

Cryptococcal meningitis: A neglected NTD?

... for cryptococcal meningitis totalled ...as cryptococcal meningitis and, as yet, neither has it fallen under the umbrella of NTD ...for cryptococcal meningitis are in the human ...

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Current diagnosis and treatment of cryptococcal meningitis without acquired immunodeficiency syndrome

Current diagnosis and treatment of cryptococcal meningitis without acquired immunodeficiency syndrome

... OF CRYPTOCOCCAL MENINGITIS The diagnosis of the CM is dependent on the medical history, clinical manifestations, imageological examination, cerebrospinal fluid parameters and laboratory ...early ...

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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

... Cryptococcal meningitis (CM) is a common and severe opportunis- tic infection primarily affecting patients with advanced HIV/AIDS caused by the basidiomycete yeasts Cryptococcus neoformans (Cn) or less ...

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Correlation of anti fungal susceptibility with clinical outcomes in patients with cryptococcal meningitis

Correlation of anti fungal susceptibility with clinical outcomes in patients with cryptococcal meningitis

... Statistical analysis was conducted using the SPSS statis- tical analysis system. If 2 or more C. neoformans strains were isolated from a patient, the first isolated strain was included in the analysis. When C. neoformans ...

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High dose fluconazole in salvage therapy for HIV uninfected cryptococcal meningitis

High dose fluconazole in salvage therapy for HIV uninfected cryptococcal meningitis

... Fig. 1 Profiles of initial therapy and salvage therapy in 44 difficult-to-treat cryptococcal meningitis patients. AmB amphotericin B; 5FC flucytosine; Vor voriconazole; L-Flu low dose fluconazole ( ≤ 400 ...

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Low CD4 count plus coma predicts cryptococcal meningitis in Tanzania

Low CD4 count plus coma predicts cryptococcal meningitis in Tanzania

... 58). Cryptococcal meningitis was diag- nosed in CSF in 24 (17%) patients by India ink stain and in 40 (29%) by latex agglutination (P = ...that meningitis was uncommon in many such patients with HIV ...

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Comparison of clinical features and prognostic factors in HIV negative adults with cryptococcal meningitis and tuberculous meningitis: a retrospective study

Comparison of clinical features and prognostic factors in HIV negative adults with cryptococcal meningitis and tuberculous meningitis: a retrospective study

... CM: Cryptococcal meningitis; CNS: Central nervous system; CrAg: Cryptococcal antigen; CSF: Cerebrospinal fluid; CT: Computed tomography; EMB: Ethambutol; HIV: Human immunodeficiency virus; IGRA: ...

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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

... Cryptococcal meningitis (CM) is a common and severe opportunis- tic infection primarily affecting patients with advanced HIV/AIDS caused by the basidiomycete yeasts Cryptococcus neoformans (Cn) or less ...

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The Challenges In The Management Of Cryptococcal Meningitis In Resource Poor Settings: Case Report

The Challenges In The Management Of Cryptococcal Meningitis In Resource Poor Settings: Case Report

... The consolidation phase of therapy currently consists of fluconazole 400-800mg every day for a duration of at least 8weeks. (Perfect et al., 2010) Most guidelines recommend starting consolidation therapy after 2weeks of ...

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Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis

Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis

... Patients needed to be either antiretroviral naive or, if not naive, off antiretrovirals for at least eight weeks prior to diagnosis of cryptococcal meningitis. Patients needed to be off fluconazole or other ...

6

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis

... Conclusions. Our work explored the hypothesis that genes that are turned on or expressed at high levels during infection belong to genetic pathways or networks important for survival and the progression of infection ...

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Early versus delayed antiretroviral treatment in HIV positive people with cryptococcal meningitis

Early versus delayed antiretroviral treatment in HIV positive people with cryptococcal meningitis

... Cryptococcal meningitis is an important opportunistic AIDS- defining infection and a major contributor to high mortality be- fore and after ART is initiated (Bicanic 2005; WHO ...include cryptococcal ...

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Analysis of cerebrospinal fluid protein concentrations of patients with cryptococcal meningitis treated with antifungal agents

Analysis of cerebrospinal fluid protein concentrations of patients with cryptococcal meningitis treated with antifungal agents

... al. Cryptococcal meningitis management in Tanzania with strict schedule of serial lumber punctures using intravenous tubing sets: an operational research ...

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Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

... of cryptococcal meningitis in non-HIV pediatric population being relatively rare, we had a small sample in the study and the small number of deaths precluding multivariate analysis of factors influencing ...

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Increased activity of the complement system in cerebrospinal fluid of the patients with Non HIV Cryptococcal meningitis

Increased activity of the complement system in cerebrospinal fluid of the patients with Non HIV Cryptococcal meningitis

... Cryptococcal meningitis (CM) is one of the most common diseases in HIV patients and other immune-compromised patients ...of cryptococcal infections is ...

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Ischemic stroke as a complication of cryptococcal meningitis and immune reconstitution inflammatory syndrome: a case report

Ischemic stroke as a complication of cryptococcal meningitis and immune reconstitution inflammatory syndrome: a case report

... Cryptococcal meningitis (CM) remains a common oppor- tunistic infection in settings with high HIV prevalence and is the leading cause of adult meningitis in Sub-Saharan Africa ...tients. ...

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Healthcare Costs and Life years Gained From Treatments Within the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) Trial on Cryptococcal Meningitis: A Comparison of Antifungal Induction Strategies in Sub Saharan Africa

Healthcare Costs and Life years Gained From Treatments Within the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) Trial on Cryptococcal Meningitis: A Comparison of Antifungal Induction Strategies in Sub Saharan Africa

... HIV-associated cryptococcal meningitis from 9 African centres in four countries (Malawi, Zambia, Tanzania and Cameroon) were enrolled between January 2013 and November ...

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Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice

Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice

... of cryptococcal meningitis due to its inability to pass through the blood–brain barrier ...against cryptococcal meningitis in a mouse ...

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CRYPTOCOCCAL meningitis in a HIV negative newly diagnosed diabetic patient: a CASE report

CRYPTOCOCCAL meningitis in a HIV negative newly diagnosed diabetic patient: a CASE report

... This lady was on the alternative regimen for treating cryptococcal meningitis in adults [11]. In the induction phase, she was given fluconazole 1200 mg od for two weeks. This was followed by 800 mg of ...

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Case Report Cryptococcal meningitis in an immunocompetent patient: a case report and review of the literatures

Case Report Cryptococcal meningitis in an immunocompetent patient: a case report and review of the literatures

... infections. Cryptococcal meningitis often begins with nonspecific clinical manifestations such as headache, dispirited and fever, hardly correlate to cryptococcal infection ...the cryptococcal ...

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