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Crystal structure of MtuHisG L with AMP bound

Insights into kinesin-1 activation from the crystal structure of KLC2 bound to JIP3

Insights into kinesin-1 activation from the crystal structure of KLC2 bound to JIP3

... the crystal structure of the KLC2 TPR bound to the cognate region of a cargo molecule, the JIP3 LZ ...this structure for our molecular under- standing of kinesin-1 recruitment and activation ...

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1.9A Crystal Structure of the Rap1a GTPase Bound to its Natural Ligand, GTP

1.9A Crystal Structure of the Rap1a GTPase Bound to its Natural Ligand, GTP

... the structure is highly conserved in this loop 9 ...helical-like structure stabilized by the carbonyl oxygen atoms of leucine 120 and glutamate 121 hydrogen bonding to the backbone amide of glutamate 123 ...

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Crystal structure of the N-myristoylated lipopeptide-bound MHC class i complex

Crystal structure of the N-myristoylated lipopeptide-bound MHC class i complex

... The myristoyl group made a sharp U-turn instead of extending into the A pocket, thereby leaving the A pocket unoccupied, and the view from the A pocket towards the B pocket pointed to a highly constricted conduit between ...

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Crystal Structure of the Dengue Virus Methyltransferase Bound to a 59-Capped Octameric RNA

Crystal Structure of the Dengue Virus Methyltransferase Bound to a 59-Capped Octameric RNA

... ring structure that encircles the two RNA octamers around a 2-fold non- crystallographic symmetry (ncs) axis, whilst the other two monomers make no contact with RNA, but participate in protein-protein interactions ...

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Crystal structure of N (3 oxo­butano­yl) L homoserine lactone

Crystal structure of N (3 oxo­butano­yl) L homoserine lactone

... 1. Chemical context N-Acyl homoserine lactones (AHLs) mediate quorum sensing in Gram-negative bacteria (Miller & Bassler, 2001; Waters & Bassler, 2005). We have previously shown that AHLs engage in n!* interactions ...

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The crystal structure and oligomeric form of Escherichia coli L,D carboxypeptidase A

The crystal structure and oligomeric form of Escherichia coli L,D carboxypeptidase A

... any bound ligand, several attempts were made using cell-wall derived peptides to detect a complex by electro-nanospray ionisation mass spectrometry ...nor crystal soaking yielded any evidence of binding ...

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A critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structure

A critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structure

... Moreover, residue N165 interacts with the adenosine base in our pseudo-product-bound crystal structure. This interaction is essential for the enzymatic reaction. Finally, we demonstrate that the ...

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Crystal structure of the human 5 HT1Bserotonin receptor bound to an inverse agonist

Crystal structure of the human 5 HT<inf>1B</inf>serotonin receptor bound to an inverse agonist

... The structure of the 5-HT 1B R binding pocket can guide the discovery of more potent and highly selective ligands for 5-HT 1B ...complex structure lacks ligand occupancy in the upper extended binding ...

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Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design

Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design

... different mechanism than most kinases because binding of an activator such as TPX2 is required in addition to phosphorylation on Thr288 [20]. The interior surface of Aurora kinases that is contacted by the DFG motif in ...

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crystal structure of a fusion protein comprising Nef and the cytoplasmic domain of CD4 bound to the tetrameric AP2 complex

crystal structure of a fusion protein comprising Nef and the cytoplasmic domain of CD4 bound to the tetrameric AP2 complex

... X-ray structure, comparative models and flexible strings of ...the crystal structure of the hexamer as a template, we imposed ‘structural equivalence’ distance restraints between pairs of residues ...

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Crystal structure of seleno L cystine di­hydro­chloride

Crystal structure of seleno L cystine di­hydro­chloride

... Numerous crystal structures are available for the dimeric amino acid cystine. In proteins it is formed by oxidation of the –SH thiol groups of two closely spaced cysteine residues, resulting in the formation of a ...

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Crystal structure of β D,L psicose

Crystal structure of β D,L psicose

... 2000). L-Psicose was prepared from allitol by microbial oxidation using Gluconobacter frateurii IFO 3254 (Takeshita et ...and L-psicose were mixed in equal amount and dissolved in hot water to give 60, 65, ...

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Crystal structure of β D,L allose

Crystal structure of β D,L allose

... Tomohiko Ishii, Tatsuya Senoo, Taro Kozakai, Kazuhiro Fukada and Genta Sakane S1. Comment Orientations of three hydrogen atoms (H1A, H2A, H4A) located on three equatorial OH groups at C-1, C-2 and C-4 positions are ...

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Crystal structure of β D,L fructose

Crystal structure of β D,L fructose

... and l -fructose (1,3,4,5,6-pentahydroxyhexan-2-one, arabino-hexulose or levulose), and it was confirmed that d -fructose (or l -fructose) formed -pyranose with a 2 C 5 (or 5 C 2 ) ...the crystal, two ...

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Crystal structure of L leucyl L isoleucine 2,2,2 tri­fluoro­ethanol monosolvate

Crystal structure of L leucyl L isoleucine 2,2,2 tri­fluoro­ethanol monosolvate

... either l -Leu or l -Phe constitute a rather heterogeneous group of crystal ...group. l -Leu- l -Ile has uniquely been obtained as two distinct hydrates, but has so far failed to ...

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Redetermination of the solvent free crystal structure of L proline

Redetermination of the solvent free crystal structure of L proline

... reported crystal structures of enantiomerically pure l - and d -proline, the racemic compound, as well as the co- crystalized structures, only marginal differences can be observed for the distances N1—C1, ...

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Crystal structure of 6 de­­oxy α L psico­furan­ose

Crystal structure of 6 de­­oxy α L psico­furan­ose

... D-psicose; Kwiecień et al., 2008; Fukada et al., 2010). This imbalance of decreasing suggests that a weaker intermolecular interaction caused by a smaller molecular density can be expected. The melting point of ...

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Crystal structure of the tripeptide N (benzyl­oxycarbon­yl)glycylglycyl L norvaline

Crystal structure of the tripeptide N (benzyl­oxycarbon­yl)glycylglycyl L norvaline

... The title tripeptide, C 17 H 23 N 3 O 6 , contains a nonproteinogenic C-terminal amino acid residue, norvaline, which is an isomer of the amino acid valine. Norvaline, unlike valine, has an unbranched side chain. The ...

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Crystal structure of dipotassium N carbodi­thio­ato L prolinate trihydrate

Crystal structure of dipotassium N carbodi­thio­ato L prolinate trihydrate

... and crystal structure of the l -proline-derived dithiocarbamate– carboxylate compound poly[tri--aqua-(-2-carboxylatopyrrolidine-1-carbodi- thioato)dipotassium], [K 2 (C 6 H 7 NO 2 S 2 )(H 2 O) 3 ] n ...

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Crystal structure of (S) sec butyl­ammonium L tartrate monohydrate

Crystal structure of (S) sec butyl­ammonium L tartrate monohydrate

... enantiopure l -tartaric acid with racemic sec-butylamine in ...with l -tartaric ...the crystal, molecules are linked through a network of O—H O and N—H O hydrogen-bonding interactions, between the ...

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