CS, chondroitin sulfate
Intravesical administration of combined hyaluronic acid (HA) and chondroitin sulfate (CS) for the treatment of female recurrent urinary tract infections: a European multicentre nested case–control study
... Four clinical studies 28–31 have been performed to investigate the ef fi cacy and tolerability of intravesically administered GAG for RUTI prophylaxis, all showing that HA alone or HA+CS instillations reduce the ...
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Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate
... reduced chondroitin sulfation in the bm mouse is the opposite of the phenotype seen in HS synthesis mutants, particularly the Ext1 gene trap mutant, in which reduction of HS results in an increased range of Hh ...
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The effect of sodium hyaluronate–chondroitin sulfate combined solution on cartilage formation in osteochondral defects of the rabbit knee: an experimental study
... + CS injections had a chondroprotective effect, and synovial membrane healing was best in this combination ...+ CS group compared to other ...+ CS group was lower in Chen et al, 18 but higher ...
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Discovery of New Roles for Chondroitin Sulfate in Neurotrophin Signaling and Retinotopic Development
... the CS-E motif are unique to specific cell types. Paradoxically, CS has been reported both to stimulate and inhibit neuronal growth, depending on the cellular ...instance, CS proteoglycans can repel ...
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Anti-inflammatory and anti-hyperuricemia properties of chicken feet cartilage: treatment on gouty arthritis animal model
... whether chondroitin sulfate (CS) and glucosamine in chicken feet cartilage powder (CFE) and aqueous extract (AE) are able to decrease serum urate level and inflammation in animal model of gouty ...
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Sodium hyaluronate and chondroitin sulfate replenishment therapy can improve nocturia in men with post-radiation cystitis: results of a prospective pilot study
... without chondroitin sulfate (CS) has been suggested as a viable treatment option to treat post-radiation LUTS ...and CS combination to treat bladder pain or post- radiation LUTS [10] and no ...
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Comparisons between two biochemical markers in evaluating periodontal disease severity: a cross-sectional study
... of chondroitin sulfate (CS) and the alkaline phosphatase (ALP) levels were determined in gingival crevicular fluid (GCF) samples collected from patients with various degrees of disease severity, ...
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acschembio.7b00885.pdf
... of chondroitin sulfate-E ...decreases CS-E and overall sulfation levels on cell-surface and secreted chondroitin sulfate proteoglycans (CSPGs), and reverses CSPG- mediated inhibition of ...
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Collagenous scaffolds supplemented with hyaluronic acid and chondroitin sulfate used for wound fibroblast and embryonic nerve cell culture
... + CS + HA scaffolds were about 4 times less populated than the Col scaffolds and ...with chondroitin sulfate and hyaluronic acid decreases the ability of the Col scaf- fold to catch both fibroblasts ...
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Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis Evidence for molecular heterogeneity and extensive molecular changes in disease
... Changes in the structure of the proteoglycan aggrecan (PG) of articular cartilage were determined immunochemically by RIA and gel chromatography and related to cartilage degeneration documented histologically by the ...
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Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11gene expression in forming surface P selectin ligands in aggressive breast cancer cells
... chains, chondroitin sulfate (CS)/dermatan sulfate (DS) PGs (CS/DS-PGs), heparan sulfate PGs and keratan sulfate PGs have been described ...of CS/DS-GAGs is found in ...
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Methodologies for the Rapid Synthesis of Hexoses and Their Application Towards a Differentially-Protected Chondroitin Sulfate Tetrasaccharide
... that CS proteoglycan expression is highly regulated in the developing ...of CS and heparan sulfate (HS) glycosaminoglycans in Caenorhabditis elegans, and these mutations are known to cause defects in ...
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Correlation between the matrix metalloproteinase-9 activity and chondroitin sulfate concentrations in tear fluid after laser <em>in situ</em> keratomileusis
... We used topical corticosteroids in the present study, which may be a factor that affected the corneal wound healing. Topical corticosteroids might affect the change in MMP-9 activity and CS concentrations and ...
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Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake
... The objective of the work reported here was therefore to synthesize and characterize poly-lactide-co-glycolide (PLGA) NPs bearing glycosaminoglycans (GAGs), namely heparin (H), hyaluronic acid (HA), chondroitin ...
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Secretome analysis of chondroitin sulfate treated chondrocytes reveals anti angiogenic, anti inflammatory and anti catabolic properties
... in CS-treated ...in CS-treated chondrocytes stimulated with IL-1 b by real time-PCR analysis, and also in cells without cytokine sti- ...5A, CS upregulates TSP1 already in the absence of ...present, ...
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Interleukin 32 induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase 1 in vitro
... and CS would influence the activation of caspase-1 induced by IL-32 or LPS in THP-1 ...or CS (Figure 5E and 5F). We also esti- mated the effect of BT and CS on caspase-1 activation using a caspase-1 ...
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Clinical effectiveness of glucosamine sulfate, chondrotin sulfate, methylsulfonylmethane phonophoresis in knee osteoarthritis
... The study was a 12-week randomized controlled trial by using random numbers. Immediately after the baseline evaluation, participants were randomly assigned to receive GS, CS, SMS PH, topical GS, CS, SMS SUS ...
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Increased urinary excretion of acidic mucopolysaccharides in exophthalmos
... The excretion of mucopolysaccharides normally found in urine chondroitin, chondroitin sulfates A and C, keratosulfate, and heparitin sulfate is increased approximately twofold in patient[r] ...
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The Binding of Cations by Chondroitin Sulfate
... In fact, if the activity coeffinow possible to calculate the activity coefficients of the sodium inside the bag, y Na+i, in the presence cients are calculated using the free sodium ion i[r] ...
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Pharmacoproteomic study of the effects of chondroitin and glucosamine sulfate on human articular chondrocytes
... by CS are proteins related to metabolism and energy ...by CS (which reduces five of these enzymes) and by the combination of both drugs (which reduces all seven glycolytic ...by CS alone (Figure 2), ...
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