cutaneous melanoma
RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb
... in cutaneous melanoma; however the functional role of RASSF8 in melanoma is not ...in melanoma cell lines and tumors of different AJCC ...metastatic melanoma lines and decreased with ...
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OSskcm: an online survival analysis webserver for skin cutaneous melanoma based on 1085 transcriptomic profiles
... Expression profiling and clinical follow-up data used in OSskcm were collected from Gene Expression Omni- bus (GEO; https ://www.ncbi.nlm.nih.gov/geo/) and The Cancer Genome Atlas (TCGA; https ://cance rgeno me.nih.gov/) ...
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Prognosis of sentinel node staged patients with primary cutaneous melanoma
... with cutaneous melanoma ...most melanoma centers worldwide [4–6] There is international consent that SLNB should be discussed with and recommended to patients when at least one of the following ...
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Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies
... Cutaneous melanoma is a very aggressive neoplasia of melanocytic origin with constantly growing incidence and mortality rates ...in melanoma development and progression by affecting key cellular ...
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Prognostic value of B cells in cutaneous melanoma
... in cutaneous melanoma To gain insight into the relationship between tumor- infiltrating B and T cell populations, we assessed the T cell receptor (TCR) repertoire using MiXCR ...
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Telomere length and survival in primary cutaneous melanoma patients
... including melanoma, emerging reports suggest that short telomeres predict poor survival in patients with different ...II cutaneous melanoma patients, we show an association between the patients with ...
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Revised U.K. guidelines for the management of cutaneous melanoma 2010
... with melanoma who have impaired health-related quality of life is comparable with other cancers, and their needs for psychosocial support are likely to be ...
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Targeted Therapy for Cutaneous Melanoma: Beyond BRAF...
... approved and experimental therapies that have demonstrated significant clinical efficacy in that molecularly-defined subtype of melanoma. While there is considerable research ongoing to identify strategies that ...
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Current state of treatment for primary cutaneous melanoma
... advanced melanoma has not been clearly defined, although there is a growing body of literature to support its use ...in cutaneous melanoma, and this yield- ed a negative result ...
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Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
... metastatic melanoma tissues and its correlation with some clinicopathologic features by using several independent ...primary melanoma tissues and benign ...of melanoma specimens showed a high NECL-5 ...
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Visual inspection for the diagnosis of cutaneous melanoma in adults
... – cutaneous melanoma; CMM - cutaneous malignant melanoma; CS – case series; CSCC – cutaneous squamous cell carcinoma; DF – dermatofibroma; Dx – diagnosis; ELM – epiluminescence ...
256
Original Article Trends in the incidence and mortality of cutaneous melanoma in Hong Kong between 1983 and 2015
... Abstract: The rapid growth of cutaneous melanoma (CM) has been observed globally, especially in the White popu- lation. However, due to the low incidence and mortality rates, epidemiological analyses for ...
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High mortality due to cutaneous melanoma in Norway: a study of prognostic factors in a nationwide cancer registry
... to cutaneous melanoma (CM) in ...Malignant Melanoma Registry (NMMR) enabled us to study patient and tumor characteristics among Norwegian patients, their relations to melanoma- specific death, ...
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Treatment of cutaneous melanoma: current approaches and future prospects
... Abstract: Melanoma is the most aggressive and deadly type of skin ...In-transit melanoma metastases may be treated locally with surgery, immunotherapy, radiation, or heated limb ...metastatic ...
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Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients
... 46 melanoma and 46 normal tissues were obtained from 92 patients at the Department of Burn and Plastic Surgery, the First Affiliated Hospital of Soochow University (FAHSU, Suzhou, China) from March 2015 to August ...
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BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs
... The youngest individuals positively screened for MBAITs in the L and W families were in their third and fourth decades of life, but all of them described to us these lesions as having been present for several years. ...
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Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients
... in melanoma cells in the primary tumor (defined as higher IRS and a high per- centage of positive cells) was strongly correlated with deeper thickness in Breslow scale and higher level in Clark ...
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Surgical Therapy of Cutaneous Melanoma
... 1992 of the technique of lymphatic mapping and SLN biopsy in melanoma cases, much controversy existed surrounding the management of the nodal basin. With the understanding that primary melanomas often spread to ...
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The forthcoming inexorable decline of cutaneous melanoma mortality in light-skinned populations
... The cutaneous malignant melanoma (hereafter termed melanoma) is the deadliest form of skin ...1985, melanoma death rates have more than doubled in all light-skinned ...in melanoma ...
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Down-regulated miR-23a Contributes to the Metastasis of Cutaneous Melanoma by Promoting Autophagy
... of melanoma. A2058 melanoma cells were transfected with siRNA against ATG12, which led to a significant reduction of ATG12 expression, ATG12-ATG5 complex formation, and LC3-II/LC3-I ratio ...of ...
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