cycle, tricarboxylic acid cycle
Structural Basis for the Interaction of 14 3 3β with Tricarboxylic Acid Cycle Intermediate Malate
... a Tricarboxylic Acid Cycle in- termediate Malate bond model might offer a new approach to further analyze insulin-independent 14-3-3/ChREBP pathway of de novo fat synthesis in the ...
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An inherited defect affecting the tricarboxylic acid cycle in a patient with congenital lactic acidosis
... hydratase appeared normal. The binding of citrate to aconitate hydratase and the activities of the NAD- and NADP-linked isocitrate dehydrogenases were also normal, while the activity of citrate synthase was slightly ...
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Genetic and Biochemical Interactions Involving Tricarboxylic Acid Cycle (TCA) Function Using a Collection of Mutants Defective in All TCA Cycle Genes
... TCA cycle enzyme erol suppression phenotype is based on a structural role interacts in some way with other proteins, such as inner of the NAD-IDH oligomeric complex in oxidative me- membrane metabolite carrier ...
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A Dysfunctional Tricarboxylic Acid Cycle Enhances Fitness of Staphylococcus epidermidis During β Lactam Stress
... activity during periods of -lactam stress may result in a fitness cost. To test this hypothesis, we performed an in vitro competition assay of the WT and the ⌬TCA mutant in TSB growth medium either in the presence or ...
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Tricarboxylic acid cycle enzymes and bicarbonate fixation in morphogenesis of Blastocladiella emersonii.
... plants. These results were considered as evidence in support of the hypothesis that bicarbonate first reversed the flow then induced multiple enzymatic lesions in the TCA cycle. Our results on mature plants ...
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Rational modification of tricarboxylic acid cycle for improving l-lysine production in Corynebacterium glutamicum
... TCA cycle in supplying l-lysine precursors and in affecting the cell growth of ...TCA cycle, either into l-lysine biosynthetic pathway or into TCA ...
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Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets
... the tricarboxylic acid (TCA) cycle and glyoxylate bypass, isocitrate dehydrogenase (ICD), involved in the TCA cycle, and ICL, involved in the glyox- ylate bypass, compete for the same ...
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Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction
... Next, we determined sfGFP signal intensities of S. Typhimurium WT, ΔfumABC, and ΔfumABC ΔglgA strains harboring the respective reporter plasmid cultured in LB broth FIG 5 Differential expression of glycogen-synthesizing ...
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Genetic Evidence for Two Carbon Fixation Pathways (the Calvin-Benson-Bassham Cycle and the Reverse Tricarboxylic Acid Cycle) in Symbiotic and Free-Living Bacteria
... FIG 1 Phylogenomic tree showing occurrence of RuBisCO (CbbM/CbbL), ATP citrate lyase (AclAB), 4-subunit 2-oxoglutarate:ferredoxin oxidoreductase (KorABCD), putative thiol:fumarate reductase (TfrAB), and 2-subunit ...
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Analysis of organic acids of tricarboxylic acid cycle in plants using GC-MS, and system modeling
... 3rd cycle (when the first formation of fumaric acid would occur) to the 12th cycle, was used to estimate the rate transfer coefficients of the difference equations (Table ...succinic acid, ...
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THE EXCRETION OF l MALIC ACID IN RELATION TO THE TRICARBOXYLIC ACID CYCLE IN THE KIDNEY
... These observations on the several mechanisms of malic acid excretion in the kidney raise several important points about the nature of the phenomena themselves and their relation to the l[r] ...
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Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells
... TCA cycle enzymes and in late, gudB (glutamate dehydrogenase), sucA (2-oxoglutarate dehydrogenase), sucC (succinyl-coenzyme A [CoA] synthetase), fumC (fumarate hydratase) TCA cycle enzymes by transducing ...
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Development and Characterization of a Condensed Reverse Tricarboxylic Acid Cycle for Use in Plants.
... crTCA cycle in plants is one of the key steps in this work. The crTCA cycle has not been found in any one organism, but is composed of enzymes from several different bacteria (Table ...crTCA cycle ...
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Studies on the Metabolism of Locust Fat Body
... They showed that a number of enzymes associated with the tricarboxylic acid cycle were present, namely, aconitase, wo-citric dehydrogenase, fumarase, malic dehydrogenase and cytochrome o[r] ...
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Complete genome sequence of Hydrogenobacter thermophilus type strain (TK-6T)
... cient hydrogen-oxidizing ability of this strain, which results in a faster generation time com- pared to other autotrophs. It is also able to grow anaerobically using nitrate as an electron acceptor when molecular ...
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Roles of microRNA on cancer cell metabolism
... MicroRNAs (miRNAs) are endogenous ~22 nt RNAs that can play important regulatory roles in a variety of biological processes. They are genome-encoded, endogenous negative regulators of translation and mRNA stability ...
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Metabolome- and genome-scale model analyses for engineering of Aureobasidium pullulans to enhance polymalic acid and malic acid production from sugarcane molasses
... Results: In this study, the production of PMA and MA from sucrose and sugarcane molasses by A. pullulans was studied in shake flasks and bioreactors. Comparative metabolome analysis of sucrose- and glucose-based ...
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Role of granulocyte oxygen products in damage of Schistosoma mansoni eggs in vitro
... reduction in acetate metabolism vs. 28.3 +/- 0.9% decrease in controls without superoxide dismutase, P less than 0.0005) and hatching (12.5 +/- 1.8% reduction, P less than 0.0005), whereas catalase and heparin had no ...
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The Metabolism of the Sea Urchin Egg
... The evidence for the operation of a tricarboxylic acid cycle in the eggs of Echinus esculentus is: a the inhibition of endogenous O2 uptake of homogenates by malonate; b the stimulation [r] ...
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