Cyst(e)amine
Oxidative stress and antibacterial properties of a graphene oxide-cystamine nanohybrid
... GO were 1 µ g/mL against E. coli and S. typhimurium, 6 µ g/mL against E. faecalis, and 4 µ g/mL against B. subtilis. These data showed that cystamine-conjugated GO had significant antibac- terial activity. A ...
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A Pharmacogenetic Discovery: Cystamine Protects Against Haloperidol-Induced Toxicity and Ischemic Brain Injury
... and cystamine coadministration returned its expression back to the baseline ...with cystamine, respec- tively, for the full-reversal scenario and ...
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Radioprotective Effects of Amifostine (WR-2721) or Cystamine on Radiation Damage and Its Repair in Rats Whole Body Exposed to Fission Neutrons
... or cystamine (disulfide of mera- captoethylamine) of Czechoslovak production were examined in whole body fission neutrons irradiated rats in the ther- mal column of reactor ...or cystamine (40 ...
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Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase
... that cystamine induces BDNF release by increasing its processing from the Golgi/TGN ...and cystamine rescue BDNF release defects induced by polyQ- huntingtin in cells and in HD ...and cystamine on ...
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Cystamine potently suppresses in vitro HIV replication in acutely and chronically infected human cells
... particles. Cystamine does not affect viral transcription, translation or protein processing; indeed, all HIV proteins are present in a pattern similar to that of nontreated ...Instead, cystamine interferes ...
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Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine cysteine mixed disulfide
... disulfide, cystamine, are equally effective in lowering cystine ...of cystamine, we have compared the fate of [35S]cystine-derived metabolites in the presence and absence of these ...and cystamine ...
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<p>A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar[5]arene and galactose derivative for targeted drug delivery</p>
... The cystamine dihydrochloride ( CA ), an important pharmaceutical intermediate that contained a disul fi de bond (sensitive to GSH) and amino groups (sensitive to pH), was ...
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Synthesis and evaluation of nanoglobule-cystamine-(Gd-DO3A), a biodegradable nanosized magnetic resonance contrast agent for dynamic contrast-enhanced magnetic resonance urography
... The DCE-MR urography was evaluated in female nude mice. Figure 2 shows the 2-dimensional (2D) coronal images crossing the heart and bladder before contrast and at various time points after contrast for nanoglobule- ...
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Effects of Cystamine, a Transglutaminase Inhibitor, in a Mouse Model of Progressive Supranuclear Palsy
... that cystamine is an in vitro TGase inhibitor (Gentile ...2004). Cystamine is known to inhibit TGase through a disulfide exchange reaction (Folk, 1980; Lorand ...amine, cystamine has a high affinity ...
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Hexanuclear Complex of Platinum(II) with Cleavage Product of Cystamine Dihydrochloride by β Mercaptoethylamine
... In the study of the complexation of Platinum(II) and Palladium(II) compounds with cystamine dihydrochloride, it has been shown that sulfur-sulfur bond of cystamine doesn’t only undergo cleavage in ...
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Enhanced Plasmonic Biosensors of Hybrid Gold Nanoparticle Graphene Oxide Based Label Free Immunoassay
... Cys: Cystamine; EDC: 1-Ethyl-3-(3- dimethylaminopropyl)carbodiimide; FEG-TEM: Field-emission gun transmission electron microscope; FTIR: Fourier-transform infrared spectrometer; GO: Graphene oxide sheet; HR-TEM: ...
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Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis
... as cystamine (or its reduced form cysteamine), can increase the expression level of F508del- CFTR protein and restore its function at the PM, either in CFTR homozygous CFBE41o- bronchial epithelial cell lines or ...
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Radioprotecteurs Chimiques (Rapport final 1 4 1964 31 12 1965) EUR 2992 = Chemical Radioprotectants (Final Report 1 4 1964 31 12 1965) EUR 2992
... 4.- La protection du bulbe pileux conférée chez le rat contre une irradiation locale est maximale IO minutes après l'injection intrapéritonéale de cystamine; elle est encore très remarqu[r] ...
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Vanin 1–/– mice show decreased NSAID and Schistosoma induced intestinal inflammation associated with higher glutathione stores
... Vanin-1 is a membrane-anchored pantetheinase highly expressed in the gut and liver. It hydrolyzes pantetheine to pantothenic acid (vitamin B5) and the low-molecular-weight thiol cysteamine. The lat- ter is believed to be ...
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Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor
... chitosan– cystamine–urocanic acid (NSC–SS–UA) and low-density lipoprotein–N-succinyl chitosan–cystamine–urocanic acid (LDL–NSC–SS–UA) micelles was elucidated via flow ...
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Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery
... of the fluorophore colors was performed (green and red). Live cell imaging started immediately after the addition of green- labeled MSN nanocarriers loaded with red-labeled siRNA to MDA-MB-231 cells. Cellular ...
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