Cysteine proteinases
ION EXCHANGERS: A USEFUL TOOL FOR SEPARATION AND SIMULTANEOUS PURIFICATION OF LYSOSOMAL CYSTEINE PROTEINASES, CATHEPSINS B, H AND L
... of cysteine proteinases such as Cathepsins B, H and L, which participate in intracellular protein degradation and are involved in various pathological ...These proteinases have been purified to ~ ...
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Cysteine proteinases from papaya (Carica papaya) in the treatment of experimental Trichuris suis infection in pigs: two randomized controlled trials
... the cysteine proteinases (CPs) from papaya (Carica papaya), collectively known as ‘papain’ , have the ability to control gastrointestinal parasites in humans, including STH ...
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Cysteine proteinases from papaya (Carica papaya) in the treatment of experimental Trichuris suis infection in pigs: two randomized controlled trials
... the cysteine proteinases (CPs) from papaya (Carica papaya), collectively known as ‘papain’ , have the ability to control gastrointestinal parasites in humans, including STH ...
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Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro
... teine proteinases that occur naturally in fruits and latices of a number of plants : papain (Sigma) and chymopapain (Sigma) from the latex of the papaya plant (Carica papaya) (Zucker et ...containing ...
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In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris
... active cysteine proteinases) caused pro- gressive damage to the cuticle, beginning with the appearance of transverse wrinkles, followed by blis- tering and, finally, less localized cuticle digestion with ...
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Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo
... Cysteine proteinases from the fruit and latex of plants, including papaya, pineapple and fig, were previously shown to have a rapid detrimental effect, in vitro, against the rodent gastrointestinal nematodes, ...
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Developing novel anthelmintics from plant cysteine proteinases
... containing cysteine proteinases Some of the earliest known medicinal anthelmintic plants include papaya (Carica papaya), figs (Ficus ...be cysteine proteinases (CP) that occur naturally in ...
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Organisation of digestion and digestive proteinases in the green mirid, Creontiades Dilutus
... serine proteinases predominate in salivary glands and secreted saliva of the green ...against cysteine proteinases did not succeed in amplifying any cysteine proteinases from the ...
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Use of Recombinant Entamoeba histolytica Cysteine Proteinase 1 To Identify a Potent Inhibitor of Amebic Invasion in a Human Colonic Model
... Cysteine proteinases are an attractive target for agents de- signed to disrupt invasion by ...specific cysteine proteinase inhibitor with these particular structural features (WRR483) to block amebic ...
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Proteinases as virulence factors in Leishmania spp infection in mammals
... of proteinases in Leishmania, as a survey of multiple databanks reveals that ...forty-four cysteine proteinases, twenty-three serine proteinases and ninety-seven metal- loproteinase ...
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VERMICIDAL ACTIVITY OF MILLETTIA PACHYCARPA ON THE NEMATODE, HETERAKIS GALLINARUM
... Albendazole reportedly caused severe damage on the cuticle of Trichinella spiralis upon in vivo treatment 19 . Surface distortion and loss of regular cuticular annulations were also observed on Brugia malayi 18 . Adult ...
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Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L An abundant transcript induced by transformation of fibroblasts
... preprocathepsin L are presented and compared to other papain family cysteine proteinases. Northern analysis shows that both human and murine cathepsin L probes hybridize to a 1.5- kb transcript in several ...
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Heterogeneity of proteinases from the hyperthermophilic archaeobacterium, Pyrococcus furiosus.
... the proteinases may not contain disulphide bonds or free thiol groups since reformation of the individual active polypeptides was observed to occur in a manner very similar to that in the control ...
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Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine cysteine mixed disulfide
... lysosomal cystine, are currently being treated with cysteamine to lower the cystine levels in their cells. In fibroblasts from these patients, cysteamine and its disulfide, cystamine, are equally effective in lowering ...
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Inhibitor of Cysteine Proteases Is Critical for Motility and Infectivity of Plasmodium Sporozoites
... ABSTRACT Malaria is transmitted when motile sporozoites are injected into the dermis by an infected female Anopheles mos- quito. Inside the mosquito vector, sporozoites egress from midgut-associated oocysts and ...
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The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies
... serine proteinases (NSPs) are granule-as- sociated enzymes that play an essential role in blood coagulation, apoptosis, inflammation, and immune responses ...
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Tissue injury in inflammation Oxidants, proteinases, and cationic proteins
... Massive stimulation of cellular production of oxygen metabolites, for example by ionophore or tetradecanol phorbol myristate TPA or PMA, will certainly lead to cell injury in vitro, in i[r] ...
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Bioorganic investigation of encapsulated Cysteine derivative into polymeric nanocarrier
... Needless to say during the last decade, countless efforts have been made to implement prominent evolution in nano-scale generation of drugs in the diagnosis and treatment of diseases. In this regard, most scientists have ...
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Cellular locations of proteinases and association with vesicles in porphyromonas gingivalis
... strains of P. gingivalis are summarized in table 1. al- though the bacteria were found to grow as the same level, slight differences were observed in the yields of vesicle and envelope. RGP and KGP were detected in all ...
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Functional Specialization and Evolution of Leader Proteinases in the Family Closteroviridae
... chimeric proteinases har- boring papain-like domains of L1 and P-Pro were not signifi- cantly different from that of the parental variant ...leader proteinases have additional specialized functions re- ...
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