cytochalasin-B
Effect of Cytochalasin B and D on Groups of Insulin Receptors and on Insulin Action in Rat Adipocytes: POSSIBLE EVIDENCE FOR A STRUCTURAL RELATIONSHIP OF THE INSULIN RECEPTOR TO THE GLUCOSE TRANSPORT SYSTEM
... synthesis. Cytochalasin B, over a concentration range of 50 nM to 5 µM, progressively inhibited the basal glucose transport system, as measured by glucose oxidation, 2-deoxyglucose transport, and 3-O- ...
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Effects of Trypsin and Cytochalasin B treatments to cell traction forces
... the cytochalasin-B and trypsin treatments suggested that the forces generated within the cells are dependent on the cytoskeleton when they are cultured on liquid crystal coated ...the cytochalasin ...
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Histamine release from human leukocytes: modulation by a cytochalasin B sensitive barrier
... Cytochalasin B, a metabolic product of several fungi, enhances up to 10-fold the sensitivity and reactivity of human leukocytes to antigen E or anti-IgE-mediated histamine ...of cytochalasin B ...
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Interactions between Antibiotics and Human Neutrophils in the Killing of Staphylococci: STUDIES WITH NORMAL AND CYTOCHALASIN B TREATED CELLS
... susceptible to killing by normal neutrophils than untreated bacteria (intracellular survival 0.17±0.04 vs. 1.5±0.38%, mean±SEM, respectively, at 35 min in 14 experiments; P < 0.01 by t test). Furthermore, this ...
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Glucose transport in carp erythrocytes: individual variation and effects of osmotic swelling, extracellular pH and catecholamines
... of cytochalasin-B-insensitive transport of glucose is markedly increased by osmotic swelling and that the transport probably occurs via a volume-activated channel that also transports various other small ...
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Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocation
... The genetically obese Zucker rat (fa/fa) is characterized by a severe resistance to the action of insulin to stimulate skeletal muscle glucose transport. The goal of the present study was to identify whether the defect ...
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Glucose uptake and metabolism by red blood cells from fish with different extracellular glucose levels
... cytochalasin B and phloretin, implying that the presence of glucose facilitated ...to cytochalasin B or phloretin treatment, but exposure to agents that increase glucose demand results in a ...
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Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
... by cytochalasin B did not affect adhesion of non-stimulated HCT-116 colon cancer cells, strongly indicate that DIAPH1-controlled cellular adhesion was not mediated by the actin-nucleating activity of ...
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Human adipocyte glucose transport system Biochemical and functional heterogeneity of hexose carriers
... the cytochalasin B binding assay to measure glucose transporters in subcellular membrane subfractions, we found that insulin induced translocation of intracellular glucose transporters to the cell ...
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Stimulated cytokineplasts from human polymorphonuclear leukocytes mobilize calcium and polymerize actin Cytoplasts made in cytochalasin B retain a defect in actin polymerization
... of cytochalasin B-treated leukocytes also increase their intracellular free calcium on stimulation, but cytoskeleton-associated actin increases by only approximately ...
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H2O2 Release from Human Granulocytes during Phagocytosis: RELATIONSHIP TO SUPEROXIDE ANION FORMATION AND CELLULAR CATABOLISM OF H2O2: STUDIES WITH NORMAL AND CYTOCHALASIN B TREATED CELLS
... and cytochalasin B-treated human granulocytes have been studied to determine some of the interrelationships between phagocytosis-induced respiration and superoxide and hydrogen peroxide formation and ...
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Cytochalasin B is a potent mitogen for chronic lymphocytic leukemia cells in vitro
... with cytochalasin B varied widely (range = ...to cytochalasin B exceeded that to pokeweed mitogen, which is believed to be a T cell-dependent B cell ...to cytochalasin B ...
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Regulation of glucose transporter specific mRNA levels in rat adipose cells with fasting and refeeding Implications for in vivo control of glucose transporter number
... transporter number and intrinsic activity (glucose turnover number). In this study, we use the human hepatoma Hep G2 glucose transporter complementary DNA clone to examine the molecular basis for these alterations. ...
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Evidence that the superoxide generating system of human leukocytes is associated with the cell surface
... phagocytosis. To investigate the possibility that the O-2--generating system is associated with the outer surface of the polymorphonuclear leukocyte plasma membrane, we have examined the effects upon O-2- production of ...
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Histamine release from human leukocytes: studies with deuterium oxide, colchicine, and cytochalasin B
... antigen. Cytochalasin B, a compound which causes the disappearance of microfilaments, had variable effects on histamine ...nor cytochalasin B altered cyclic AMP levels in ...
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Dynamics of Insulin Release and Microtubular Microfilamentous System I EFFECT OF CYTOCHALASIN B
... of cytochalasin B upon both glucose- and sulfonylurea-induced insulin release was investigated in the perfused isolated ...pancreas. Cytochalasin B failed to affect the basal rate of insulin ...
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Involvement of p32 and Microtubules in Alteration of Mitochondrial Functions by Rubella Virus
... Besides RV there are two prominent examples of viruses that induce cluster formation of mitochondria. African swine fever virus induces the migration of mitochondria to the site of virus assembly in order to provide ...
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Requirements for different components of the host cell cytoskeleton distinguish ecotropic murine leukemia virus entry via endocytosis from entry via surface fusion.
... inhibitors cytochalasin D, a specific inhibitor of actin polymer- ization, and nocodazole, a specific inhibitor of tubulin poly- merization into microtubules (10, 29, ...with cytochalasin D (10, 29, ...of ...
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Requirement for an Intact T-Cell Actin and Tubulin Cytoskeleton for Efficient Assembly and Spread of Human Immunodeficiency Virus Type 1
... Our data obtained with actin remodeling inhibitors are con- sistent with two previous studies from Sasaki and colleagues, who demonstrated that treatment of the HIV-1-infected, im- mortalized T-cell line H9 or the ...
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HIV 1 Assembly, Release and Maturation
... not inhibit viral entry but rather interfere with late stages of HIV-1 assembly. This inhibitory effect has been ini- tially identified for the lead compounds BA and BVM. These compounds, when added to a HIV-1 producing ...
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