cytokeratin 18
Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis
... Caspase-cleaved cytokeratin-18; CCL18: CC-chemokine ligand 18; DAB: Diaminobenzidine; DLCO: Diffusing capacity for carbon monoxide; DNA: Deoxyribonucleic acid; ELISA: Enzyme-linked immunosorbent ...
9
High serum levels of caspase-cleaved cytokeratin-18 are associated with malignant middle cerebral artery infarction patient mortality
... uncertain. Cytokeratin-18 exists mainly in the intracytoplasmic cytoskeleton of epithelial tissue and during apoptosis citokeratin-18 is cleaved by caspases and appears as CCCK-18 into the ...
6
Total and caspase-cleaved cytokeratin 18 in chronic cholecystitis: A prospective study
... (caspase-cleaved cytokeratin 18) was studied in these patients with M30 Apoptosense ELISA and the total cytokerarin 18 (both derived from apoptosis and necrosis) with M65 ...total cytokeratin ...
5
Caspase cleaved cytokeratin 18 and tumour regression in gastro oesophageal adenocarcinomas treated with neoadjuvant chemotherapy
... Cytokeratin-18 (CK-18) is commonly expressed in epithelial tumours. Caspase- cleaved CK-18 is expressed in cancer cells undergoing apoptosis following chemotherapy. Caspase-cleaved ...
6
Serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B
... In recent years, it has become clear that serum levels of a fragment of cytokeratin 18 (the so- called caspase-cleaved cytokeratin 18 [CK18-Asp396]) reflect the amount of programmed cell death ...
7
The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells.
... Since vimentin repolymerizes effectively in both mock-infected and infected samples, we conclude that the inhibition of cytokeratin filament polymerization in infected cells is a specifi[r] ...
8
Three are better than one: plasminogen receptors as cancer theranostic targets
... CK8: Cytokeratin 8; CK18: Cytokeratin 18; CK19: Cytokeratin 19; CRCC: Chromophobe renal cell carcinoma; EMT: Epithelial mesenchymal transition; EGF: Epidermal growth factor; ENOA: ...
11
Abstract
... for cytokeratin 18 (M30) was detected in 52 ...CK 18 positivity in ovarian carcinoma showed inter− and intra−tumoral ...of cytokeratin 18 or p53 expression and clinicopathological ...
8
Extracellular vesicles: the next generation of biomarkers for liquid biopsy-based prostate cancer diagnosis
... AF4: asymmetrical flow field-flow fractionation; AQP2: aquaporin-2; BPH: benign prostatic hyperplasia; PCa: prostate cancer; CK18: cytokeratin 18; CTCs: circulating tumour cells; cfDN[r] ...
18
Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails
... HNF4α, cytokeratin 18 (CK18), cytokeratin 19 (CK19)], and hepatocyte markers [albumin (ALB), alpha-1 antitrypsin (A1AT), apolipoprotein A2 (APOA2), ASGR1, CYP1A2, CYP2B6, CYP3A4, and so on] were ...
15
Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play
... A Chinese group found that the serum levels of cytokeratin-18 M30 fragment Ck-18-M30; a marker of hepatocyte apoptosis fibroblast-21 FGF-21; related to decreasing blood glucose, lipid an[r] ...
9
Platelet-rich plasma improves therapeutic effects of menstrual blood-derived stromal cells in rat model of intrauterine adhesion
... day 18 post-treatment, a statistically significant increase of EdU+ cells was found in the epithelium and stroma of the traumatized uteri in M group, P group, and MP group compared to control N ...day 18 ...
12
Download Download PDF
... Cytokeratins are family of intermediate filaments with molecular weight between 40 and 68 kDa that are found in almost all epithelial cells. Epithelium of colonic mucosa contains low molecular weight proteins i.e. CK 8, ...
7
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma.pdf
... the cytokeratin 8/18 expression pattern seen in basal- like ...tumors. Cytokeratin 8/18 is a marker typically expressed in the luminal epithelial cells of the breast and is not expressed in ...
8
Novel patient derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin
... and cytokeratin 19 (CK19) [1:100, anti-mouse with rodent block (Dakocytomation)]; Mist-1 [1:2000] and cleaved caspase-3 (CC3) [1:100 hi pH, anti-rabbit (Cell Signaling, Beverly, MA)]; amylase [1:1000, anti-rabbit ...
14
Seeking biomarkers for acute graft-versus-host disease: where we are and where we are heading?
... Regulatory T cells (Tregs), as the main cell subsets that play an immunosuppressive role, are also a focus. It was reported that the low numbers or proportions of Tregs in peripheral blood are associated with aGVHD [15, ...
10
Cytokeratin 8 Is an Epithelial Cell Receptor for Pet, a Cytotoxic Serine Protease Autotransporter of Enterobacteriaceae
... ABSTRACT The group of proteins known as serine protease autotransporters of Enterobacteriaceae (SPATE) is a growing family of serine proteases secreted to the external milieu by the type V secretion system. Pet toxin and ...
12
Primary intrahepatic cholangiocarcinoma with sarcomatous stroma: case report and review of the literature
... for cytokeratin-7 (CK7), cytokeratin-19 (CK19), CD56, and epithelial membrane antigen (EMA), but negative for hepatocellular carcin- oma markers such as Glypican-3 (date not ...
9
A rare bladder cancer - small cell carcinoma: review and update
... Immunohistochemistry has a central role for the diagno- sis of SCCB through the staining of tumour components by antibody markers targeting the following antigens: neuron-specific enolase (NSE), chromogranin, synapto- ...
11
Lymphoepithelial Carcinoma with Special Reference to Nasopharynx.
... IHC was done with pan cytokeratin ,and lymphoma panel .cytokeratin was positive in tumor cells and CD45,CD20,CD3 were positive in non neoplastic lymphocytes .This case was again stained [r] ...
79