cytokeratin 5
Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis
... Anti-human Cytokeratin 5/6, clone D5/16 B4 (Lot ...than 5 years experience of reporting his- topathology and immunohistochemistry and they were blinded by other histopathological features of the ...
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Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor negative, cytokeratin 5 positive subpopulation in luminal disease
... HER2, Cytokeratin 5 (CK5) and epidermal growth factor receptor-1 (EGFR) - can serve as surrogates to classify breast cancers into subtypes analo- gous to those defined by gene ...
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c-Kit and Cytokeratin 5/6 Immunohistochemical Investigations in Egyptian Human Breast Cancer
... of cytokeratin 5/6 (CK5/6), and mast/stem cell growth factor receptor (c-KIT or CD117) was performed on formalin- fixed, paraffin-embedded breast cancer ...
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An analysis of Cyclin D1, Cytokeratin 5/6 and Cytokeratin 8/18 expression in breast papillomas and papillary carcinomas
... CK 5/6 staining, and one for Cyclin D1 and CK 8/ 18 ...a Cytokeratin 5/6 (CK 5/6) or Cytokeratin 8/18 (CK 8/18) antibody, both of which were purchased from Maxim Bio (Fuzhou, Fujian, ...
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Cytokeratin 5/6 and cytokeratin 8/18 expression in triple negative breast cancers: clinicopathologic significance in South Asian population
... basal cytokeratin 5/6, C–kit, proliferation cluster and low expression of Her2neu and hormone receptor related genes ...CK 5/6 expression varies from 24 to 72% in TNBC as reported in previous studies ...
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The Role of Cytokeratin 5/6 in Differential Diagnosis of Prostate Tumors
... In this study 26 (86.6%) benign samples were positive for CK5/6 stain cytoplasm brown color and 28 (93.3%) malignant samples were negative for CK5/6 (P= 0.00), this indicates that there was relation between CK5/6 and ...
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Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant Basal- HER2 subtype of breast cancer
... We utilized Cox’s proportional-hazards regression model to assess DFS (Table 4). Univariate analysis revealed that the presence of the basal-like phenotype was a significant predictor of a worse 5-year DFS (hazard ...
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Gene expression in “young adult type” breast cancer: a retrospective analysis
... and cytokeratin 5/6 is particularly prevalent in young women under 40 as compared to older ...of cytokeratin 5, 6A and 6B in basal tumors [5], but to our knowledge this is the first ...
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Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations
... CK5/6: cytokeratin 5/6; CRC: colorectal cancer; DAPI: 4 ’ : 6 ’ -diamidino-2-phenylindole; EGFR: epidermal growth factor receptor; ER: estrogen receptor; FISH: fluorescence in-situ hybridization; HER2: ...
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Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma.pdf
... is presumed that most of these tumors are basal-like tumors; however, these studies did not formally demonstrate this relationship and other classic myoepithelial markers were typically not examined. All of the 18 known ...
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Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells
... Additional file 4: Figure S4. Showing CDCP1 knockdown blocks HpSC migration, related to Fig. 5. A Migration of HpSCs was evaluated using transwell chambers. HpSCs transfected with CDCP1 siRNA, negative control ...
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Case Report Decidualization of intranodal endometriosis in a postmenopausal woman
... of cytokeratin, epithelial mem- brane antigen, p63, desmin and calretinin (Figure ...for cytokeratin (CK) AE1/AE3 (Figure 3E), CAM ...CK 5/6, CK20 and ...
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Immunohistochemical Evaluation of Cytokeratin 19 and Calretinin in Odontogenic Cysts and Tumors
... Christian Stoll, C arolin Stollen werk et al 2005, evaluated cy tokeratin expression patterns as an additional tool for characterization of different cy sts as the histomorphologic appearance often is not decisive. ...
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Utility of cytokeratin 20 and Ki 67 as markers of urothelial dysplasia
... Reactive urothelial atypia (RUA) can be difficult to differen- tiate from dysplastic urothelium. The goal was to evaluate the efficacy of cytokeratin 20 (CK20), Ki-67 and E-cadherin (E-Cad) in this regard. Fifty ...
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Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
... for 5 min, incubated with TrypLE Express (Life Technologies) at 37 °C for 8 min, and finally purified through a 70 μm cell-strainer (BD Biosciences, San Jose, ...
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The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells.
... Since vimentin repolymerizes effectively in both mock-infected and infected samples, we conclude that the inhibition of cytokeratin filament polymerization in infected cells is a specifi[r] ...
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Basal cytokeratins in breast tumours among BRCA1, BRCA2and mutation negative breast cancer families
... Because of differences in antibodies, staining and tissue processing procedures in different studies, it is difficult to compare findings between studies directly. For example, we chose a cut-off point (>10%) for CKs ...
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Immunohistochemical expression of Cytokeratin 17 in Histological section of Sudanese Female with breast Cancer
... would not be expected to be effective on basal breast cancers because this subtype typically expresses neither of these proteins. Although diagnostic antibodies that work in formalin- fixed, paraffin-embedded archival ...
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Total and caspase-cleaved cytokeratin 18 in chronic cholecystitis: A prospective study
... (caspase-cleaved cytokeratin 18) was studied in these patients with M30 Apoptosense ELISA and the total cytokerarin 18 (both derived from apoptosis and necrosis) with M65 ...total cytokeratin 18) was also ...
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Metachronous rectal metastasis from primary transverse colon cancer: a case report
... Case presentation: The patient underwent a laparoscopic extended right hemicolectomy for primary transverse colon cancer. Histopathological examination showed moderately differentiated adenocarcinoma, and the tumor was ...
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