Cytolethal distending toxin
Prevalence of Cytolethal Distending Toxin Production in Periodontopathogenic Bacteria
... Cytolethal distending toxin (CDT) is a newly identified virulence factor produced by several pathogenic bacteria implicated in chronic ...the toxin varied considerably among these ...unique ...
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Prediction of CTL epitope, in silico modeling and functional analysis of cytolethal distending toxin (CDT) protein of Campylobacter jejuni
... Prediction of CTL epitope, in silico modeling and functional analysis of cytolethal distending toxin CDT protein of Campylobacter jejuni Arun G Ingale1* and Susumu Goto2*.. Abstract Back[r] ...
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The cytolethal distending toxin from the chancroid bacterium Haemophilus ducreyi induces cell cycle arrest in the G2 phase
... potent cytolethal distending toxin produced by Haemophilus ducreyi is a putative virulence factor in the pathogenesis of ...other cytolethal distend- ing toxins, these cells accumulated in the ...
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Characterization of Cytolethal Distending Toxin of Campylobacter Species Isolated from Captive Macaque Monkeys
... between cytolethal distending toxin and disease is incompletely under- ...for cytolethal distending toxin ...of cytolethal distending toxin was confirmed on ...
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Cytolethal Distending Toxin Genes inCampylobacter jejuni and Campylobacter coliIsolates: Detection and Analysis by PCR
... and toxin production (12, 30, ...is cytolethal distending toxin (CDT), a toxic activity first shown by Johnson and Lior (10) to be produced by several Campylobacter ...
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Association of Cytolethal Distending Toxin Locus cdtB with Enteropathogenic Escherichia coli Isolated from Patients with Acute Diarrhea in Calcutta, India
... Among Escherichia coli strains isolated from stool specimens from patients with acute diarrhea, 1.4% were found to harbor cdtB by use of enrichment cytolethal distending toxin (CDT) PCR. These ...
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Evolution of a Self-Inducible Cytolethal Distending Toxin Type V-Encoding Bacteriophage from Escherichia coli O157:H7 to Shigella sonnei
... Some cdt genes are located within the genome of inducible or cryptic bacteriophages, but there is little information about the mechanisms of cdt transfer because of the reduced number of inducible Cdt phages described. ...
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The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi
... Our data indicate that S-CDT significantly impacts the out- come of infection with NTS serotypes at the cellular level. It will be important to further assess the role of S-CDT in vivo to determine the implications of ...
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Shiga Toxin, Cytolethal Distending Toxin, and Hemolysin Repertoires in Clinical Escherichia coli O91 Isolates
... V; the toxin was regularly expressed and was lethal to human microvascular endothelial cells. Infection with STEC O91:H21 was associated with hemolytic-uremic syndrome (P ⴝ 0.0015), whereas strains of the other ...
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Characterization of the cytolethal distending toxin (typhoid toxin) in non-typhoidal Salmonella serovars
... Methods: A comparative genomics approach was performed to characterize sequence conservation of the typhoid toxin (TT), encoded in the CdtB‑islet, between Salmonella Typhi and NTS serovars. The cytotoxic activity ...
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Prevalence of cdt Gene in Campylobacter jejuni Strains Isolated from Surface Waters of Rasht, Iran
... and toxin genes of Campylobacter jejuni and Campylobacter coli isolates from Danish pigs and cattle and cytolethal distending toxin production of the ...
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Production of Cytolethal Distending Toxins by Pathogenic Escherichia coli Strains Isolated from Human and Animal Sources: Establishment of the Existence of a New cdt Variant (Type IV)
... Three types of cytolethal distending toxin (CDT), namely, CDT-I, CDT-II, and CDT-III, have been described in Escherichia coli. Using primers designed for the detection of sequences common to the cdtB ...
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“Botulinum Toxin: A Review on Its Transition from a Lethal Poison to a Magical Therapeutic Drug” by S Amarnath, Arun Sharma, K Rathna Kumar, K Hemanandhini, S Ramaswamy, India.
... Botulinum toxin is a neurotoxin produced by Clostridium botulinum which causes ...this toxin and characterization of the microbe’s culture ...botulinum toxin along with the side effect profile and ...
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Toxin Inactivation in Toxin/Antitoxin Systems
... the toxin genes indicate the initial toxicity for MqsR, GhoT, RalR, and ...the toxin and antitoxin (blue diamonds and lines), and toxin alone (triangles and red lines) with 1mM ...the toxin ...
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New Players in the Toxin Field: Polymorphic Toxin Systems in Bacteria
... polymorphic toxin with its cognate immunity protein ...the toxin can be found upstream of the toxin gene (such as cdiB) and orphan modules encoding alternate toxic domains (CT), and their cognate ...
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Diminished Clostridium difficile toxin A sensitivity in newborn rabbit ileum is associated with decreased toxin A receptor
... In that toxin A is the major cause of intestinal damage with this organism, we compared toxin A receptor binding and biological effects in newborn vs adult rabbit ileum.. Purified toxin [r] ...
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High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial [ISRCTN24242669]
... ARDS = adult respiratory distress syndrome; CDP = continuous distending pressure; CI = confidence interval; CV = conventional mechanical ventilation; FiO2 = fraction of inspired oxygen; [r] ...
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Diagnosis of Clostridium difficile infection by toxigenic culture and PCR assay
... Clostridium difficile is an important cause of noso- comial infections. Symptoms of C. difficile infection (CDI) range from asymptomatic carriage to mild di- arrhea, colitis, severe life threatening pseudomem- branous ...
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Inadvertent Administration of Positive End-Distending Pressure During Nasal Cannula Flow
... Improvements in breathing patterns, specifically improvement in TAM synchrony, in infants with res- piratory insufficiency may occur related to a multi- factorial interaction of chest wa[r] ...
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The pitfalls of laboratory diagnostics of Clostridium difficile infection
... Negative, Toxin B-Negative, Binary Toxin-Positive Clostridium difficile in a Young Patient. 117[r] ...
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