Cytopathic Effect
Selective depletion of stored calcium by thapsigargin blocks rotavirus maturation but not the cytopathic effect.
... When we probed the conformation of VP7 in thapsigargin- treated cells with a set of MAbs against VP7, we found a decreased recognition of this protein. Although no formal proof is available whether these MAbs recognize ...
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Avian Sarcoma and Leukosis Virus Cytopathic Effect in the Absence of TVB Death Domain Signaling
... The cytopathic effect (CPE) seen with some subgroups of avian sarcoma and leukosis virus (ASLV) is associated with viral Env activation of the death-promoting activity of TVB (a tumor necrosis factor ...
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Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein.
... 1 Attenuation of Human Immunodeficiency Virus Type 1 Cytopathic Effect by a Mutation Affecting the Transmembrane Envelope Glycoprotein MARK KOWALSKI,' LOUISE BERGERON,' TATYANA DORFMAN,'[r] ...
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Acanthamoeba mediated cytopathic effect correlates with MBP and AhLBP mRNA expression
... cytopathic effect even when the incubation time was prolonged to 1 ...trophozoite-mediated cytopathic effect is due to three independent mechanisms: direct cytolysis, phagocytosis and ...
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Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells
... During an adenoviral infection, E1A is the first gene to be expressed by the virus. Two main spliced forms are pro- duced, 12S and 13S, which encode proteins differing in the presence of a zinc finger domain (Conserved ...
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Mengovirus-Induced Cytopathic Effect in L-Cells: Protective Effect of Interferon
... 1 \ S DISCUSSION VThe data reported here indicate that two effects of mengovirus on L cells, the production of CPE 1Jo\ and cut-off of host cell protein synthesis, are 40 affected by int[r] ...
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The Feline Calicivirus Leader of the Capsid Protein Is Associated with Cytopathic Effect
... no effect on the recovery of virus (Table 1), and the CPE was similar to that of the ...recover cytopathic viruses by P3, although all three passages were positive by RT-PCR, indicating low levels of ...
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Induction of cytopathic effect and cytokines in coxsackievirus B3 infected murine astrocytes
... Levels of IL-1β, TNF-α, IL-6, and CXCL10 were assessed using ELISA kits: IL-1β (Cat.No. BM6002), TNF-α (Cat. No. BM607/2), and IL-6 (Cat.No. BM603/2) were pur- chased from eBioscience. CXCL10 was purchased from Bender ...
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“Hairiness” is a Facsimile of Reorganized Cytoskeletons: A Cytopathic Effect of Coxiella burnetii
... as cytopathic effects that are not target cell ...similar cytopathic effects should be addressed in other diseases, such as myopathies, B-cell dyscrasias, and autoimmune ...
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Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo
... The cytopathic effect (CPE) was determined by three dif- ferent methods. At first, tumor cells such as NCIH460, SW1990, SMMC-7721 and Hela were plated into 24-well plates and either infected with different ...
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Variant-Specific Tropism of Human Herpesvirus 6 in Human Astrocytes
... for cytopathic effect (CPE), intra- and extracellular viral DNA load, the presence of viral particles by electronic microscopy, mRNA transcription, and viral protein ...
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Antiviral and virucidal activities of Duabanga grandiflora leaf extract against Pseudorabies virus in vitro
... infection via the cytopathic effect, plaque reduction, viral replication, and virucidal activities. However, the anti- viral activities of the D. grandiflora leaf extracts are dependent on the solvent used ...
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Epidermodysplasia verruciformis: revision of a model of carcinogenic disease
... In flat warts lesions from malignant form of EV, the viral cytopathic effect is observed from the suprabasal layer to the upper layers of the epidermis, which is char- acteristic of the [r] ...
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Assay of human interferon in Vero cells by several methods
... Four methods for the assay of human interferon in Vero cells were compared based on the inhibition of viral cytopathic effect CPE in tubes, the inhibition of CPE in microplates, the redu[r] ...
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Simultaneous detection of respiratory syncytial virus and human metapneumovirus by one-step multiplex real-time RT-PCR in patients with respiratory symptoms
... syncytial cytopathic pattern [7, 15 – ...any cytopathic effect (CPE) is apparent, particu- larly following primary isolation, which often takes more than 10 days ...
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Polyacetal Carboxylic Acids: a New Group of Antiviral Polyanions
... Our screening procedure for detection of antiviral effects of polyanions comprised four test systems: i inhibition of cytopathic effect of VSV, ii induction of interferon in vivo, iii in[r] ...
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The C-Terminal Domain of Chikungunya Virus nsP2 Independently Governs Viral RNA Replication, Cytopathicity, and Inhibition of Interferon Signaling
... and cytopathic effect (CPE), the inhibition of JAK-STAT signaling, viral replication, and nuclear translocation of nsP2, we set out to determine whether or not these character- istics of nsP2 are ...
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Nucleolin Interacts with the Feline Calicivirus 3′ Untranslated Region and the Protease-Polymerase NS6 and NS7 Proteins, Playing a Role in Virus Replication
... Our coprecipitation assay using recombinant NV NS6/7 pro- tein showed that this protein and nucleolin can associate to form a complex, although whether this is a direct protein- protein interaction or mediated by an ...
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Virucidal activity of Garcinia parvifolia leaf extracts in animal cell culture
... Background: Garcinia species contain bioactive compounds such as flavonoids, xanthones, triterpernoids, and benzophenones with antibacterial, antifungal, anti-inflammatory, and antioxidant activities. In addition, many ...
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Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Escherichia coli
... They were selected for the study because their sonic extracts were necrotizing in rabbit skin and produced a cytopathic effect of multinucleation in Vero or HeLa cell cultures.. These st[r] ...
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